TargetScan_13 megaCluster: 1 Residual: 0.63 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_13	1	0.63	9	0.006	0.597261	0.997

Members

Displaying 1 - 28 of 28

100038522 DNA methyltransferase 3A, opposite strand Details for - - DNA methyltransferase 3A, opposite strand GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100038522 Tuberculist Genomic Region	100042807 eukaryotic translation initiation factor 3, subunit J2 Details for - - eukaryotic translation initiation factor 3, subunit J2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100042807 Tuberculist Genomic Region
100043424 predicted gene 14005 Details for - - predicted gene 14005 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100043424 Tuberculist Genomic Region	100504417 predicted gene, 20215 Details for - - predicted gene, 20215 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504417 Tuberculist Genomic Region
109115 suppressor of Ty 3 Details for AC164546.1 - suppressor of Ty 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109115 Tuberculist Genomic Region	11988 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Details for - - solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11988 Tuberculist Genomic Region
12176 BCL2/adenovirus E1B interacting protein 3 Details for - - BCL2/adenovirus E1B interacting protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12176 Tuberculist Genomic Region	12608 CCAAT/enhancer binding protein (C/EBP), beta Details for RP24-151H6.1 - CCAAT/enhancer binding protein (C/EBP), beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12608 Tuberculist Genomic Region
14733 glypican 1 Details for - - glypican 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14733 Tuberculist Genomic Region	16071 immunoglobulin kappa constant Details for - - immunoglobulin kappa constant GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16071 Tuberculist Genomic Region
171254 vomeronasal 1 receptor 198 Details for RP23-124G18.5 - vomeronasal 1 receptor 198 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 171254 Tuberculist Genomic Region	18037 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18037 Tuberculist Genomic Region
229003 helicase with zinc finger 2, transcriptional coactivator Details for RP23-401M24.3 - helicase with zinc finger 2, transcriptional coactivator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229003 Tuberculist Genomic Region	258331 olfactory receptor 1330 Details for RP23-149E24.6 - olfactory receptor 1330 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 258331 Tuberculist Genomic Region
329540 RIKEN cDNA 8430427H17 gene Details for RP23-204D17.2 - RIKEN cDNA 8430427H17 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 329540 Tuberculist Genomic Region	378472 vault RNA component 5 Details for - - vault RNA component 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 378472 Tuberculist Genomic Region
433287 predicted gene 15455 Details for - - predicted gene 15455 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 433287 Tuberculist Genomic Region	55948 stratifin Details for RP23-137L22.11-001 - stratifin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 55948 Tuberculist Genomic Region
626534 tubulin, alpha 1C pseudogene Details for - - tubulin, alpha 1C pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 626534 Tuberculist Genomic Region	65963 transmembrane protein 176B Details for - - transmembrane protein 176B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65963 Tuberculist Genomic Region
667712 predicted gene 8777 Details for - - predicted gene 8777 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667712 Tuberculist Genomic Region	67893 transmembrane protein 86A Details for - - transmembrane protein 86A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67893 Tuberculist Genomic Region
68949 RIKEN cDNA 1500012F01 gene Details for - - RIKEN cDNA 1500012F01 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68949 Tuberculist Genomic Region	69664 keratin associated protein 1-5 Details for RP23-272C1.5 - keratin associated protein 1-5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69664 Tuberculist Genomic Region
78654 RIKEN cDNA 1700066C05 gene Details for - - RIKEN cDNA 1700066C05 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78654 Tuberculist Genomic Region	100313519 small nucleolar RNA, C/D box 17 Details for - - small nucleolar RNA, C/D box 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100313519 Tuberculist Genomic Region
11812 apolipoprotein C-I Details for - - apolipoprotein C-I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11812 Tuberculist Genomic Region	382551 CD300 antigen like family member H Details for RP23-331L12.8 - CD300 antigen like family member H GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 382551 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q6_01_M00931, SP1_MA0079.2, V_SP1_03_M02281, V_SP4_Q5_M01273, V_ZFP281_01_M01597, V_SP1_Q2_01_M00933, V_SP1_Q4_01_M00932	1, 1, 1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
3.7	CCWCNNCCTCC	NA	1900	CCCCACCCCCNG	SP1_MA0079.2, Klf4_MA0039.2, V$ZFP281_01_M01597, V$SP1_03_M02281, V$SP4_Q5_M01273, V$SP1_02_M01303, V$ZNF219_01_M01122, V$SP1_Q2_01_M00933, V$CACD_01_M01113, V$ZFP281_04_M02831, V$UF1H3BETA_Q6_M01068, V$SP1_Q6_M00196, V$ZBP89_Q4_M01816, V$GKLF_02_M01588, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$CACBINDINGPROTEIN_Q6_M00720, V$EKLF_Q5_M01874, V$CKROX_Q2_M01175, V$MAZR_01_M00491, V$KLF7_03_M02773, V$KROX_Q6_M00982, V$MZF1_01_M00083, V$MAZ_Q6_M00649, V$GLI3_Q5_01_M01657, V$EGR2_Q6_M02092, V$SP1SP3_Q4_M01219, V$GC_01_M00255, V$CACCCBINDINGFACTOR_Q6_M00721, V$SP4_03_M02810, V$FKLF_Q5_M01837, V$EGR1_Q6_M01873, V$MAZ_Q6_01_M02023, V$EGR1_04_M02848, Zfp281.2, Klf7.1, Sp4.1, Egr1.2, Zfp740.1, Bcl6b.2, Egr1.1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.07	GCGACC	NA	1.08	CCCGYTGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.68	CACNAA	NA	NA	0.95	GTGAGACA	mmu-mir-5615-3p	7mer_m8

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-let-7b	0.181818	0.0000394

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