TargetScan_134 megaCluster: 10 Residual: 0.18 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_134	10	0.18	15	0	0.939474	0

Members

Displaying 1 - 38 of 38

104725 serine palmitoyltransferase, small subunit A Details for - - serine palmitoyltransferase, small subunit A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104725 Tuberculist Genomic Region	17692 male-specific lethal 3 homolog (Drosophila) Details for RP23-125I7.1 - male-specific lethal 3 homolog (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17692 Tuberculist Genomic Region
227059 solute carrier family 39 (zinc transporter), member 10 Details for - - solute carrier family 39 (zinc transporter), member 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227059 Tuberculist Genomic Region	231327 phosphoribosyl pyrophosphate amidotransferase Details for - - phosphoribosyl pyrophosphate amidotransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231327 Tuberculist Genomic Region
23874 phenylalanyl-tRNA synthetase, beta subunit Details for - - phenylalanyl-tRNA synthetase, beta subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23874 Tuberculist Genomic Region	26465 zinc finger protein 146 Details for - - zinc finger protein 146 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26465 Tuberculist Genomic Region
68659 family with sequence similarity 198, member B Details for - - family with sequence similarity 198, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68659 Tuberculist Genomic Region	68801 ELOVL family member 5, elongation of long chain fatty acids (yeast) Details for - - ELOVL family member 5, elongation of long chain fatty acids (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68801 Tuberculist Genomic Region
94219 cyclin M2 Details for - - cyclin M2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 94219 Tuberculist Genomic Region	104130 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 Details for RP23-333P16.5 - NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104130 Tuberculist Genomic Region
107769 transmembrane 6 superfamily member 1 Details for - - transmembrane 6 superfamily member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107769 Tuberculist Genomic Region	11428 aconitase 1 Details for RP23-9F23.1 - aconitase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11428 Tuberculist Genomic Region
117198 influenza virus NS1A binding protein Details for - - influenza virus NS1A binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 117198 Tuberculist Genomic Region	14263 flavin containing monooxygenase 5 Details for - - flavin containing monooxygenase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14263 Tuberculist Genomic Region
14873 glutathione S-transferase omega 1 Details for - - glutathione S-transferase omega 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14873 Tuberculist Genomic Region	213068 transmembrane protein 71 Details for - - transmembrane protein 71 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213068 Tuberculist Genomic Region
21855 translocase of inner mitochondrial membrane 17b Details for RP23-198C2.2 - translocase of inner mitochondrial membrane 17b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21855 Tuberculist Genomic Region	21974 topoisomerase (DNA) II beta Details for - - topoisomerase (DNA) II beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21974 Tuberculist Genomic Region
26451 ribosomal protein L27A Details for - - ribosomal protein L27A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26451 Tuberculist Genomic Region	319934 SET binding factor 2 Details for - - SET binding factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 319934 Tuberculist Genomic Region
330503 predicted gene 5113 Details for - - predicted gene 5113 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330503 Tuberculist Genomic Region	50995 ubiquitin-like modifier activating enzyme 2 Details for RP23-349I9.1 - ubiquitin-like modifier activating enzyme 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50995 Tuberculist Genomic Region
54138 ataxin 10 Details for - - ataxin 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54138 Tuberculist Genomic Region	56248 adenylate kinase 3 Details for - - adenylate kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56248 Tuberculist Genomic Region
56298 atlastin GTPase 2 Details for - - atlastin GTPase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56298 Tuberculist Genomic Region	66071 ethylmalonic encephalopathy 1 Details for - - ethylmalonic encephalopathy 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66071 Tuberculist Genomic Region
67442 retinol saturase (all trans retinol 13,14 reductase) Details for - - retinol saturase (all trans retinol 13,14 reductase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67442 Tuberculist Genomic Region	67493 methyltransferase like 16 Details for RP23-174M12.2 - methyltransferase like 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67493 Tuberculist Genomic Region
67973 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) Details for - - M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67973 Tuberculist Genomic Region	68559 p53 and DNA damage regulated 1 Details for RP23-88J10.1 - p53 and DNA damage regulated 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68559 Tuberculist Genomic Region
68631 crystallin, lambda 1 Details for - - crystallin, lambda 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68631 Tuberculist Genomic Region	72117 N(alpha)-acetyltransferase 50, NatE catalytic subunit Details for - - N(alpha)-acetyltransferase 50, NatE catalytic subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72117 Tuberculist Genomic Region
72981 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) Details for - - protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72981 Tuberculist Genomic Region	74196 tetratricopeptide repeat domain 27 Details for - - tetratricopeptide repeat domain 27 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74196 Tuberculist Genomic Region
75416 NOP14 nucleolar protein Details for - - NOP14 nucleolar protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75416 Tuberculist Genomic Region	76582 importin 11 Details for - - importin 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76582 Tuberculist Genomic Region
320506 LMBR1 domain containing 2 Details for - - LMBR1 domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320506 Tuberculist Genomic Region	74164 nuclear transcription factor, X-box binding 1 Details for RP23-28I8.5 - nuclear transcription factor, X-box binding 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74164 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_IPF1_01_M01233	0.105263	0.0000463

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000027	AAARWAANSAAA	NA	1	AGGKGGGYGGGG	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$GKLF_02_M01588, V$KLF7_03_M02773, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$SP1_03_M02281, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$CACD_01_M01113, V$SP1_Q6_01_M00931, V$ZFP281_01_M01597, V$ZFP281_04_M02831, V$SP1_02_M01303, V$KROX_Q6_M00982, V$GC_01_M00255, V$SP4_03_M02810, V$EKLF_Q5_M01874, V$ZNF219_01_M01122, V$ZFP740_03_M02834, V$CKROX_Q2_M01175, V$SP1SP3_Q4_M01219, V$MOVOB_01_M01104, V$MAZ_Q6_M00649, V$ZBP89_Q4_M01816, V$MAZR_01_M00491, V$EGR2_Q6_M02092, V$CACCCBINDINGFACTOR_Q6_M00721, V$ASCL2_04_M02841, V$SMAD4_04_M02898, V$EGR1_Q6_M01873, V$MAZ_Q6_01_M02023, V$SP1_01_M00008, V$MZF1_01_M00083, V$GLI3_Q5_01_M01657, V$ZNF515_01_M01231, V$CACBINDINGPROTEIN_Q6_M00720, V$WT1_Q6_M01118, V$FKLF_Q5_M01837, V$UF1H3BETA_Q6_M01068, V$SOX14_04_M02901, V$BCL6B_04_M02844, V$E2F3_Q6_M02089, V$EGR1_06_M02744, Klf7.1, Zfp281.2, Sp4.1, Zfp740.1, Ascl2.2, Smad3.1, Egr1.1, Sox13.2, Bcl6b.2, Zfp410.1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1, KLF13_C2H2_full_monomeric_18_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.37	ACGGCG	NA	1.4	GTCTCGCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.45	CGTGTG	NA	NA	0.58	ATNGTGTG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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