TargetScan_143 megaCluster: 3 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_143	3	0.22	10	0	0.824001	0.005

Members

Displaying 1 - 21 of 21

108058 calcium/calmodulin-dependent protein kinase II, delta Details for - - calcium/calmodulin-dependent protein kinase II, delta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108058 Tuberculist Genomic Region	13518 dystonin Details for - - dystonin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13518 Tuberculist Genomic Region
17937 Ngfi-A binding protein 2 Details for - - Ngfi-A binding protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17937 Tuberculist Genomic Region	18550 furin (paired basic amino acid cleaving enzyme) Details for - - furin (paired basic amino acid cleaving enzyme) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18550 Tuberculist Genomic Region
23921 SH2B adaptor protein 2 Details for - - SH2B adaptor protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23921 Tuberculist Genomic Region	24056 SH3-domain binding protein 5 (BTK-associated) Details for - - SH3-domain binding protein 5 (BTK-associated) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24056 Tuberculist Genomic Region
24088 toll-like receptor 2 Details for - - toll-like receptor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24088 Tuberculist Genomic Region	26570 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Details for - - solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26570 Tuberculist Genomic Region
26908 eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked Details for - - eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26908 Tuberculist Genomic Region	67702 ring finger protein 149 Details for - - ring finger protein 149 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67702 Tuberculist Genomic Region
71409 formin-like 2 Details for RP23-282A22.1 - formin-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71409 Tuberculist Genomic Region	72504 TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor Details for - - TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72504 Tuberculist Genomic Region
12874 carboxypeptidase D Details for RP23-396O3.1 - carboxypeptidase D GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12874 Tuberculist Genomic Region	16402 integrin alpha 5 (fibronectin receptor alpha) Details for - - integrin alpha 5 (fibronectin receptor alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16402 Tuberculist Genomic Region
18788 serine (or cysteine) peptidase inhibitor, clade B, member 2 Details for - - serine (or cysteine) peptidase inhibitor, clade B, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18788 Tuberculist Genomic Region	20442 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 Details for - - ST3 beta-galactoside alpha-2,3-sialyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20442 Tuberculist Genomic Region
225028 mitogen-activated protein kinase kinase kinase kinase 3 Details for - - mitogen-activated protein kinase kinase kinase kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225028 Tuberculist Genomic Region	234839 piezo-type mechanosensitive ion channel component 1 Details for - - piezo-type mechanosensitive ion channel component 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234839 Tuberculist Genomic Region
381290 ATPase, Ca++ transporting, plasma membrane 4 Details for - - ATPase, Ca++ transporting, plasma membrane 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381290 Tuberculist Genomic Region	57783 TNFAIP3 interacting protein 1 Details for - - TNFAIP3 interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57783 Tuberculist Genomic Region
67197 zinc finger CCHC-type and RNA binding motif 1 Details for - - zinc finger CCHC-type and RNA binding motif 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67197 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_E2F2_03_M02742, E2F2.1	0.571429, 0.571429	0.0000108

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.93	CAAAMGAGRAAA	NA	1.9	GGGCGGNGCTG	V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$SP2_01_M01783, V$SP1_Q2_01_M00933, Klf7.1, Zfp410.1, Bcl6b.2

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.27	CGGCTG	NA	1.48	GGCCGCNC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.85	TACTCTAA	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-767	0.444444	0.000068

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