TargetScan_146 megaCluster: 4 Residual: 0.15 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_146	4	0.15	15	0	0.962178	0

Members

Displaying 1 - 29 of 29

12111 biglycan Details for RP23-95K12.7 - biglycan GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12111 Tuberculist Genomic Region	14219 connective tissue growth factor Details for - - connective tissue growth factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14219 Tuberculist Genomic Region
19248 protein tyrosine phosphatase, non-receptor type 12 Details for - - protein tyrosine phosphatase, non-receptor type 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19248 Tuberculist Genomic Region	20592 lysine (K)-specific demethylase 5D Details for - - lysine (K)-specific demethylase 5D GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20592 Tuberculist Genomic Region
268490 LSM12 homolog (S. cerevisiae) Details for RP23-167N11.2 - LSM12 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 268490 Tuberculist Genomic Region	26900 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked Details for - - DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26900 Tuberculist Genomic Region
53621 CCR4-NOT transcription complex, subunit 4 Details for - - CCR4-NOT transcription complex, subunit 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53621 Tuberculist Genomic Region	75956 serine/arginine repetitive matrix 2 Details for - - serine/arginine repetitive matrix 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75956 Tuberculist Genomic Region
104103 antisense Igf2r RNA Details for - - antisense Igf2r RNA GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104103 Tuberculist Genomic Region	11475 actin, alpha 2, smooth muscle, aorta Details for - - actin, alpha 2, smooth muscle, aorta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11475 Tuberculist Genomic Region
11816 apolipoprotein E Details for - - apolipoprotein E GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11816 Tuberculist Genomic Region	12552 cadherin 11 Details for - - cadherin 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12552 Tuberculist Genomic Region
12816 collagen, type XII, alpha 1 Details for - - collagen, type XII, alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12816 Tuberculist Genomic Region	140780 BMP2 inducible kinase Details for - - BMP2 inducible kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 140780 Tuberculist Genomic Region
16007 cysteine rich protein 61 Details for - - cysteine rich protein 61 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16007 Tuberculist Genomic Region	19219 prostaglandin E receptor 4 (subtype EP4) Details for - - prostaglandin E receptor 4 (subtype EP4) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19219 Tuberculist Genomic Region
20530 solute carrier family 31, member 2 Details for RP23-64F17.2 - solute carrier family 31, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20530 Tuberculist Genomic Region	20841 zinc finger protein 143 Details for - - zinc finger protein 143 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20841 Tuberculist Genomic Region
218699 PX domain containing serine/threonine kinase Details for - - PX domain containing serine/threonine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218699 Tuberculist Genomic Region	22290 ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome Details for - - ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22290 Tuberculist Genomic Region
24056 SH3-domain binding protein 5 (BTK-associated) Details for - - SH3-domain binding protein 5 (BTK-associated) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24056 Tuberculist Genomic Region	244895 pseudopodium-enriched atypical kinase 1 Details for - - pseudopodium-enriched atypical kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244895 Tuberculist Genomic Region
26908 eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked Details for - - eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26908 Tuberculist Genomic Region	269799 C-type lectin domain family 4, member a1 Details for - - C-type lectin domain family 4, member a1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269799 Tuberculist Genomic Region
407243 transmembrane protein 189 Details for RP23-118A2.8 - transmembrane protein 189 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 407243 Tuberculist Genomic Region	58194 SH3-domain kinase binding protein 1 Details for RP23-39I7.6 - SH3-domain kinase binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58194 Tuberculist Genomic Region
67739 solute carrier family 48 (heme transporter), member 1 Details for - - solute carrier family 48 (heme transporter), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67739 Tuberculist Genomic Region	69562 cyclin-dependent kinase 13 Details for - - cyclin-dependent kinase 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69562 Tuberculist Genomic Region
75089 UHRF1 (ICBP90) binding protein 1-like Details for - - UHRF1 (ICBP90) binding protein 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75089 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_CEBP_01_M00159	0.321429	0.00000807

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000038	AAAAAAAAACAT	Srf.2	0.04	CGCCCCKCCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$UF1H3BETA_Q6_M01068, V$SP4_Q5_M01273, V$ZFP281_01_M01597, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$SP1_02_M01303, V$ZNF219_01_M01122, V$ZFP281_04_M02831, V$GC_01_M00255, V$EGR1_Q6_M01873, V$MAZ_Q6_01_M02023, V$CKROX_Q2_M01175, V$SP4_03_M02810, V$ZBP89_Q4_M01816, V$MAZ_Q6_M00649, V$EGR1_06_M02744, V$GKLF_02_M01588, V$KROX_Q6_M00982, V$MAZR_01_M00491, V$SP1SP3_Q4_M01219, V$KLF7_03_M02773, V$WT1_Q6_01_M02036, V$ETF_Q6_M00695, V$BCL6B_04_M02844, V$ZFP740_03_M02834, V$ZFP410_04_M02936, V$KLF15_Q2_M01714, V$CACD_01_M01113, V$SP1_01_M00008, V$EGR_Q6_M00807, V$SMAD4_04_M02898, V$SP2_01_M01783, V$INSM1_01_M02268, V$FPM315_01_M01587, V$EKLF_Q5_M01874, V$CACBINDINGPROTEIN_Q6_M00720, V$E2F3_Q6_M02089, Zfp281.2, Sp4.1, Egr1.1, Klf7.1, Zfp740.1, Zfp410.1, Bcl6b.2, Smad3.1, Zif268.1, Zbtb7b.1, Ascl2.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.23	CAGCCG	NA	1.34	GACGCGNC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.62	GTTACNCT	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-153	0.833333	0.0000000524

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1971	0.416667	0.000038

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