TargetScan_170 megaCluster: 9 Residual: 0.20

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_170	9	0.20	15	0	0.931343	0

Members

Displaying 1 - 42 of 42

TFBS DB TF

TFs	percTargets	pValue
V_SP1_01_M00008	0.928571	0.00000568

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000000000000063	AAAAAAWAAACA	Foxj3_forkhead_DBD_dimeric_13_1	4.6	GCCCCSCCCNCC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_03_M02281, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$GC_01_M00255, V$ZFP281_01_M01597, V$GKLF_02_M01588, V$SP2_01_M01783, V$KLF7_03_M02773, V$MAZR_01_M00491, V$ZNF219_01_M01122, V$UF1H3BETA_Q6_M01068, V$ZFP281_04_M02831, V$ZBP89_Q4_M01816, V$SP1_02_M01303, V$MAZ_Q6_01_M02023, V$SP1_01_M00008, V$SP1SP3_Q4_M01219, V$CKROX_Q2_M01175, V$SMAD4_04_M02898, V$SP4_03_M02810, V$EGR1_Q6_M01873, V$EGR_Q6_M00807, V$KROX_Q6_M00982, V$ZFP740_03_M02834, V$CACD_01_M01113, V$EGR1_06_M02744, V$CACBINDINGPROTEIN_Q6_M00720, V$E2F3_Q6_M02089, V$MAZ_Q6_M00649, V$ETF_Q6_M00695, V$WT1_Q6_01_M02036, V$BTEB3_Q5_M01865, V$BCL6B_04_M02844, V$WT1_Q6_M01118, V$FPM315_01_M01587, V$GKLF_Q4_M01835, V$EKLF_Q5_M01874, V$SP4_04_M02914, V$FKLF_Q5_M01837, V$ZFP410_04_M02936, Klf7.1, Zfp281.2, Smad3.1, Sp4.1, Zfp740.1, Egr1.1, Bcl6b.2, Sp4.2, Zfp410.1, Zif268.1, Ascl2.2, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, ZNF740_C2H2_full_monomeric_10_1, KLF14_C2H2_DBD_monomeric_14_1, Zfp740_C2H2_DBD_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.04	CGCGAA	NA	1.26	TGCGGCGT	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.57	CCGGCA	NA	NA	0.63	TGGANGNG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-125b-5p, mmu-miR-125a-5p, mmu-miR-351	0.617647	0.000064

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1962	0.457143	0.000000691

223753 ceramide kinase Details for - - ceramide kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223753 Tuberculist Genomic Region	320528 vacuolar protein sorting 13C (yeast) Details for - - vacuolar protein sorting 13C (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320528 Tuberculist Genomic Region
56541 hyaluronic acid binding protein 4 Details for - - hyaluronic acid binding protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56541 Tuberculist Genomic Region	68281 RIKEN cDNA 4930430F08 gene Details for - - RIKEN cDNA 4930430F08 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68281 Tuberculist Genomic Region
68731 ribosome binding factor A Details for - - ribosome binding factor A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68731 Tuberculist Genomic Region	71904 progestin and adipoQ receptor family member VII Details for - - progestin and adipoQ receptor family member VII GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71904 Tuberculist Genomic Region
71972 dynamin binding protein Details for - - dynamin binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71972 Tuberculist Genomic Region	76967 RIKEN cDNA 2700049A03 gene Details for - - RIKEN cDNA 2700049A03 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76967 Tuberculist Genomic Region
106068 solute carrier family 45, member 4 Details for - - solute carrier family 45, member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106068 Tuberculist Genomic Region	11781 adaptor-related protein complex AP-4, mu 1 Details for - - adaptor-related protein complex AP-4, mu 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11781 Tuberculist Genomic Region
17826 family with sequence similarity 89, member B Details for - - family with sequence similarity 89, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17826 Tuberculist Genomic Region	18479 p21 protein (Cdc42/Rac)-activated kinase 1 Details for - - p21 protein (Cdc42/Rac)-activated kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18479 Tuberculist Genomic Region
20111 ribosomal protein S6 kinase polypeptide 1 Details for RP23-256C7.2 - ribosomal protein S6 kinase polypeptide 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20111 Tuberculist Genomic Region	209131 sorting nexin family member 30 Details for RP23-451K12.1 - sorting nexin family member 30 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209131 Tuberculist Genomic Region
210029 meteorin, glial cell differentiation regulator-like Details for RP23-274J5.3 - meteorin, glial cell differentiation regulator-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210029 Tuberculist Genomic Region	215201 TRM2 tRNA methyltransferase 2B Details for RP23-162B19.2 - TRM2 tRNA methyltransferase 2B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 215201 Tuberculist Genomic Region
223921 achalasia, adrenocortical insufficiency, alacrimia Details for - - achalasia, adrenocortical insufficiency, alacrimia GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223921 Tuberculist Genomic Region	22619 sialic acid acetylesterase Details for - - sialic acid acetylesterase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22619 Tuberculist Genomic Region
226409 zinc finger, RAN-binding domain containing 3 Details for - - zinc finger, RAN-binding domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226409 Tuberculist Genomic Region	226744 consortin, connexin sorting protein Details for - - consortin, connexin sorting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226744 Tuberculist Genomic Region
22700 zinc finger protein 40 Details for RP24-440M15.1 - zinc finger protein 40 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22700 Tuberculist Genomic Region	228607 mitochondrial antiviral signaling protein Details for RP23-387C21.3 - mitochondrial antiviral signaling protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228607 Tuberculist Genomic Region
228880 zinc finger, MYND-type containing 8 Details for RP23-108D12.1 - zinc finger, MYND-type containing 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228880 Tuberculist Genomic Region	229521 synaptotagmin XI Details for - - synaptotagmin XI GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229521 Tuberculist Genomic Region
230101 glucosidase beta 2 Details for RP23-191F22.2 - glucosidase beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230101 Tuberculist Genomic Region	26416 mitogen-activated protein kinase 14 Details for RP24-137E7.1 - mitogen-activated protein kinase 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26416 Tuberculist Genomic Region
269587 erythrocyte protein band 4.1 Details for RP23-13A13.5 - erythrocyte protein band 4.1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269587 Tuberculist Genomic Region	380912 zinc finger protein 395 Details for - - zinc finger protein 395 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380912 Tuberculist Genomic Region
408022 primase and polymerase (DNA-directed) Details for - - primase and polymerase (DNA-directed) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 408022 Tuberculist Genomic Region	50798 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Details for RP23-209M8.6 - glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50798 Tuberculist Genomic Region
66073 thioredoxin domain containing 12 (endoplasmic reticulum) Details for RP23-31C9.2 - thioredoxin domain containing 12 (endoplasmic reticulum) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66073 Tuberculist Genomic Region	66682 trafficking protein particle complex 5 Details for - - trafficking protein particle complex 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66682 Tuberculist Genomic Region
68145 Ewing tumor-associated antigen 1 Details for RP23-353E13.3 - Ewing tumor-associated antigen 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68145 Tuberculist Genomic Region	68366 transmembrane protein 129 Details for - - transmembrane protein 129 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68366 Tuberculist Genomic Region
68428 STEAP family member 3 Details for - - STEAP family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68428 Tuberculist Genomic Region	69091 vacuolar protein sorting 26 homolog B (yeast) Details for - - vacuolar protein sorting 26 homolog B (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69091 Tuberculist Genomic Region
69662 RIKEN cDNA 2310061I04 gene Details for RP24-180B11.5 - RIKEN cDNA 2310061I04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69662 Tuberculist Genomic Region	70719 histocompatibility (minor) HA-1 Details for - - histocompatibility (minor) HA-1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70719 Tuberculist Genomic Region
72017 cytochrome b5 reductase 1 Details for - - cytochrome b5 reductase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72017 Tuberculist Genomic Region	72194 F-box and leucine-rich repeat protein 20 Details for RP23-309H19.11-002 - F-box and leucine-rich repeat protein 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72194 Tuberculist Genomic Region
74478 sorting nexin 29 Details for - - sorting nexin 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74478 Tuberculist Genomic Region	76467 methionine sulfoxide reductase B2 Details for RP23-34E4.2 - methionine sulfoxide reductase B2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76467 Tuberculist Genomic Region

TargetScan_170 megaCluster: 9 Residual: 0.20

Summary

Members

Details for - - ceramide kinase

Details for - - vacuolar protein sorting 13C (yeast)

Details for - - hyaluronic acid binding protein 4

Details for - - RIKEN cDNA 4930430F08 gene

Details for - - ribosome binding factor A

Details for - - progestin and adipoQ receptor family member VII

Details for - - dynamin binding protein

Details for - - RIKEN cDNA 2700049A03 gene

Details for - - solute carrier family 45, member 4

Details for - - adaptor-related protein complex AP-4, mu 1

Details for - - family with sequence similarity 89, member B

Details for - - p21 protein (Cdc42/Rac)-activated kinase 1

Details for RP23-256C7.2 - ribosomal protein S6 kinase polypeptide 1

Details for RP23-451K12.1 - sorting nexin family member 30

Details for RP23-274J5.3 - meteorin, glial cell differentiation regulator-like

Details for RP23-162B19.2 - TRM2 tRNA methyltransferase 2B

Details for - - achalasia, adrenocortical insufficiency, alacrimia

Details for - - sialic acid acetylesterase

Details for - - zinc finger, RAN-binding domain containing 3

Details for - - consortin, connexin sorting protein

Details for RP24-440M15.1 - zinc finger protein 40

Details for RP23-387C21.3 - mitochondrial antiviral signaling protein

Details for RP23-108D12.1 - zinc finger, MYND-type containing 8

Details for - - synaptotagmin XI

Details for RP23-191F22.2 - glucosidase beta 2

Details for RP24-137E7.1 - mitogen-activated protein kinase 14

Details for RP23-13A13.5 - erythrocyte protein band 4.1

Details for - - zinc finger protein 395

Details for - - primase and polymerase (DNA-directed)

Details for RP23-209M8.6 - glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Details for RP23-31C9.2 - thioredoxin domain containing 12 (endoplasmic reticulum)

Details for - - trafficking protein particle complex 5

Details for RP23-353E13.3 - Ewing tumor-associated antigen 1

Details for - - transmembrane protein 129

Details for - - STEAP family member 3

Details for - - vacuolar protein sorting 26 homolog B (yeast)

Details for RP24-180B11.5 - RIKEN cDNA 2310061I04 gene

Details for - - histocompatibility (minor) HA-1

Details for - - cytochrome b5 reductase 1

Details for RP23-309H19.11-002 - F-box and leucine-rich repeat protein 20

Details for - - sorting nexin 29

Details for RP23-34E4.2 - methionine sulfoxide reductase B2

GO Terms

3p UTR PITA