TargetScan_182 megaCluster: 3 Residual: 0.23 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_182	3	0.23	14	0	0.873372	0

Members

Displaying 1 - 29 of 29

100503890 PET100 homolog (S. cerevisiae) Details for - - PET100 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503890 Tuberculist Genomic Region	11787 amyloid beta (A4) precursor protein-binding, family B, member 2 Details for - - amyloid beta (A4) precursor protein-binding, family B, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11787 Tuberculist Genomic Region
15902 inhibitor of DNA binding 2 Details for - - inhibitor of DNA binding 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15902 Tuberculist Genomic Region	16176 interleukin 1 beta Details for RP23-384K11.2 - interleukin 1 beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16176 Tuberculist Genomic Region
16798 large tumor suppressor Details for - - large tumor suppressor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16798 Tuberculist Genomic Region	216783 olfactory receptor 320 Details for RP23-128D9.8 - olfactory receptor 320 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216783 Tuberculist Genomic Region
327987 mediator complex subunit 13 Details for RP23-50E4.3 - mediator complex subunit 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 327987 Tuberculist Genomic Region	546325 predicted gene 5936 Details for RP23-459K15.9 - predicted gene 5936 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 546325 Tuberculist Genomic Region
59043 WD repeat and SOCS box-containing 2 Details for - - WD repeat and SOCS box-containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 59043 Tuberculist Genomic Region	74007 BTB (POZ) domain containing 11 Details for - - BTB (POZ) domain containing 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74007 Tuberculist Genomic Region
100034251 WAP four-disulfide core domain 17 Details for RP23-430I21.1 - WAP four-disulfide core domain 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100034251 Tuberculist Genomic Region	13713 ELK3, member of ETS oncogene family Details for - - ELK3, member of ETS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13713 Tuberculist Genomic Region
14630 glutamate-cysteine ligase, modifier subunit Details for - - glutamate-cysteine ligase, modifier subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14630 Tuberculist Genomic Region	15251 hypoxia inducible factor 1, alpha subunit Details for - - hypoxia inducible factor 1, alpha subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15251 Tuberculist Genomic Region
15277 hexokinase 2 Details for - - hexokinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15277 Tuberculist Genomic Region	15387 heterogeneous nuclear ribonucleoprotein K Details for - - heterogeneous nuclear ribonucleoprotein K GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15387 Tuberculist Genomic Region
18578 phosphodiesterase 4B, cAMP specific Details for RP23-57D24.1 - phosphodiesterase 4B, cAMP specific GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18578 Tuberculist Genomic Region	20310 chemokine (C-X-C motif) ligand 2 Details for - - chemokine (C-X-C motif) ligand 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20310 Tuberculist Genomic Region
218756 solute carrier family 4, sodium bicarbonate cotransporter, member 7 Details for - - solute carrier family 4, sodium bicarbonate cotransporter, member 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218756 Tuberculist Genomic Region	240396 mex3 homolog C (C. elegans) Details for - - mex3 homolog C (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240396 Tuberculist Genomic Region
244871 zinc finger CCCH type containing 12C Details for - - zinc finger CCCH type containing 12C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244871 Tuberculist Genomic Region	26374 ring finger and WD repeat domain 2 Details for mCG_124354 - ring finger and WD repeat domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26374 Tuberculist Genomic Region
26570 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Details for - - solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26570 Tuberculist Genomic Region	606736 RIKEN cDNA C920009B18 gene Details for - - RIKEN cDNA C920009B18 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 606736 Tuberculist Genomic Region
622976 predicted gene 6377 Details for RP23-252O5.3 - predicted gene 6377 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 622976 Tuberculist Genomic Region	666737 RIKEN cDNA 4632427E13 gene Details for - - RIKEN cDNA 4632427E13 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 666737 Tuberculist Genomic Region
68142 INO80 homolog (S. cerevisiae) Details for RP23-46P4.10-001 - INO80 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68142 Tuberculist Genomic Region	74178 serine/threonine kinase 40 Details for RP23-365D10.1 - serine/threonine kinase 40 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74178 Tuberculist Genomic Region
791293 predicted gene 9948 Details for - - predicted gene 9948 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 791293 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SOX40_04_M02908	0.12	0.0000052

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.03	CCNCCCCCGCCC	Klf4_MA0039.2, SP1_MA0079.2, V$UF1H3BETA_Q6_M01068, V$ZNF219_01_M01122, V$SP1_02_M01303, V$ZFP281_04_M02831, V$SP4_Q5_M01273, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$SP1_Q2_01_M00933, V$SP1_Q6_01_M00931, V$ZFP281_01_M01597, V$EGR1_Q6_M01873, V$CACD_01_M01113, V$NFE4_Q5_M02105, V$SP1_03_M02281, V$KLF7_03_M02773, V$ZFP740_03_M02834, V$KLF15_Q2_M01714, V$CKROX_Q2_M01175, V$WT1_Q6_01_M02036, V$GKLF_02_M01588, V$MAZR_01_M00491, V$SP1_Q4_01_M00932, V$EGR1_06_M02744, V$MOVOB_01_M01104, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$SP1_Q6_M00196, V$GC_01_M00255, V$ETF_Q6_M00695, V$SP1_01_M00008, V$MAZ_Q6_M00649, V$FKLF_Q5_M01837, Zfp281.2, Klf7.1, Zfp740.1, Egr1.1, Bcl6b.2, Ascl2.2, Zfp410.1	0.0024	TTTYCNNTTTYA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.09	CGACCG	NA	1.43	CCGAGAGC

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.93	TTTTCN	NA	NA	0.73	TTTTCNNN	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-345-3p	0.7	0.0000204

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-291a-5p	0.545455	0.0000099

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