TargetScan_184 megaCluster: 8 Residual: 0.40

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_184 8 0.40 13 0.001 0.701448 0.592

Members

Displaying 1 - 26 of 26
105171 arrestin domain containing 3

Details for - - arrestin domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 105171

Tuberculist Genomic Region

14874 glutathione transferase zeta 1 (maleylacetoacetate isomerase)

Details for - - glutathione transferase zeta 1 (maleylacetoacetate isomerase)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14874

Tuberculist Genomic Region

17966 neighbor of Brca1 gene 1

Details for RP23-382C19.1 - neighbor of Brca1 gene 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17966

Tuberculist Genomic Region

217666 L-2-hydroxyglutarate dehydrogenase

Details for - - L-2-hydroxyglutarate dehydrogenase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217666

Tuberculist Genomic Region

26370 centrin 2

Details for RP23-307G22.3 - centrin 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26370

Tuberculist Genomic Region

271697 cyclin-dependent kinase 15

Details for - - cyclin-dependent kinase 15

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 271697

Tuberculist Genomic Region

76972 RIKEN cDNA 2810008D09 gene

Details for - - RIKEN cDNA 2810008D09 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76972

Tuberculist Genomic Region

100503883 predicted gene, 17484

Details for - - predicted gene, 17484

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100503003

Tuberculist Genomic Region

106581 predicted gene, 19941

Details for - - predicted gene, 19941

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100503883

Tuberculist Genomic Region

107047 integrin alpha FG-GAP repeat containing 3

Details for - - integrin alpha FG-GAP repeat containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 106581

Tuberculist Genomic Region

17314 proteasome (prosome, macropain) assembly chaperone 2

Details for - - proteasome (prosome, macropain) assembly chaperone 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107047

Tuberculist Genomic Region

19212 O-6-methylguanine-DNA methyltransferase

Details for - - O-6-methylguanine-DNA methyltransferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17314

Tuberculist Genomic Region

19331 phosphotriesterase related

Details for RP23-415C3.1 - phosphotriesterase related

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19212

Tuberculist Genomic Region

212627 RAB19, member RAS oncogene family

Details for - - RAB19, member RAS oncogene family

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19331

Tuberculist Genomic Region

219022 phosphoribosyl pyrophosphate synthetase-associated protein 2

Details for RP23-278F12.1 - phosphoribosyl pyrophosphate synthetase-associated protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 212627

Tuberculist Genomic Region

22718 tetratricopeptide repeat domain 5

Details for - - tetratricopeptide repeat domain 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 219022

Tuberculist Genomic Region

26879 zinc finger protein 60

Details for - - zinc finger protein 60

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22718

Tuberculist Genomic Region

319263 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1

Details for - - UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26879

Tuberculist Genomic Region

54122 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1

Details for - - protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 319263

Tuberculist Genomic Region

67046 UEV and lactate/malate dehyrogenase domains

Details for - - UEV and lactate/malate dehyrogenase domains

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54122

Tuberculist Genomic Region

67574 TBC1 domain family, member 7

Details for - - TBC1 domain family, member 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67046

Tuberculist Genomic Region

68038 asparagine-linked glycosylation 13

Details for RP23-159H8.5 - asparagine-linked glycosylation 13

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67574

Tuberculist Genomic Region

69623 chitinase domain containing 1

Details for - - chitinase domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68038

Tuberculist Genomic Region

71599 zinc finger protein 33B

Details for - - zinc finger protein 33B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69623

Tuberculist Genomic Region

74192 SUMO/sentrin specific peptidase 8

Details for - - SUMO/sentrin specific peptidase 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71599

Tuberculist Genomic Region

Details for RP23-244N6.5 - actin related protein 2/3 complex, subunit 5-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74192

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
NA

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.1 CCCCRCCCMCW Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, Egr1_MA0162.1, V$KLF7_03_M02773, V$ZFP281_01_M01597, V$SP1_Q2_01_M00933, V$GKLF_02_M01588, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$CACD_01_M01113, V$MAZ_Q6_01_M02023, V$SP4_03_M02810, V$SP1_03_M02281, V$ZBP89_Q4_M01816, V$CKROX_Q2_M01175, V$MAZ_Q6_M00649, V$UF1H3BETA_Q6_M01068, V$KROX_Q6_M00982, V$SP1_02_M01303, V$EGR1_Q6_M01873, V$EKLF_Q5_M01874, V$ZFP740_03_M02834, V$EGR_Q6_M00807, V$ZFP281_04_M02831, V$CACBINDINGPROTEIN_Q6_M00720, V$EGR1_06_M02744, V$SP1_01_M00008, V$CACCCBINDINGFACTOR_Q6_M00721, V$WT1_Q6_M01118, V$NGFIC_01_M00244, V$WT1_Q6_01_M02036, V$MAZR_01_M00491, V$EGR1_02_M01972, V$GCM_Q2_M00634, V$GLI3_Q5_01_M01657, V$SP1SP3_Q4_M01219, V$FKLF_Q5_M01837, V$MOVOB_01_M01104, V$EGR2_Q6_M02092, V$ZNF219_01_M01122, V$SP2_01_M01783, V$E2F3_Q6_M02089, V$BCL6B_04_M02844, V$KLF15_Q2_M01714, V$SMAD4_04_M02898, V$SOX14_04_M02901, Klf7.1, Sp4.1, Zfp740.1, Zfp281.2, Egr1.1, Zif268.1, Bcl6b.2, Sox13.2, Smad3.1, Ascl2.2, Zfp410.1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1, EGR2_C2H2_full_monomeric_15_1 64 TGNAAGRAGAN NA

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.33 GGCGGA Egr1.1, Smad3.1, Bcl6b.2 1.41 CGCACCGT NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.54 GTANGC NA NA 0.75 AGNGAGTA NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
NA

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