TargetScan_210 megaCluster: 3 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_210	3	0.22	15	0	0.91372	0

Members

Displaying 1 - 27 of 27

100503596 predicted gene, 19789 Details for - - predicted gene, 19789 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503596 Tuberculist Genomic Region	102103 mitochondrial tumor suppressor 1 Details for - - mitochondrial tumor suppressor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 102103 Tuberculist Genomic Region
107607 nucleotide-binding oligomerization domain containing 1 Details for - - nucleotide-binding oligomerization domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107607 Tuberculist Genomic Region	12986 colony stimulating factor 3 receptor (granulocyte) Details for RP23-140F18.1 - colony stimulating factor 3 receptor (granulocyte) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12986 Tuberculist Genomic Region
15466 histamine receptor H2 Details for - - histamine receptor H2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15466 Tuberculist Genomic Region	16068 interleukin 18 binding protein Details for - - interleukin 18 binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16068 Tuberculist Genomic Region
17187 Max protein Details for - - Max protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17187 Tuberculist Genomic Region	18729 paired-Ig-like receptor A6 Details for - - paired-Ig-like receptor A6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18729 Tuberculist Genomic Region
231002 pleckstrin homology domain containing, family N member 1 Details for - - pleckstrin homology domain containing, family N member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231002 Tuberculist Genomic Region	23960 2'-5' oligoadenylate synthetase 1G Details for - - 2'-5' oligoadenylate synthetase 1G GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23960 Tuberculist Genomic Region
245536 predicted gene 614 Details for RP23-440J15.1 - predicted gene 614 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245536 Tuberculist Genomic Region	27056 interferon regulatory factor 5 Details for - - interferon regulatory factor 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27056 Tuberculist Genomic Region
27215 5-azacytidine induced gene 2 Details for - - 5-azacytidine induced gene 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27215 Tuberculist Genomic Region	320148 RIKEN cDNA B430306N03 gene Details for - - RIKEN cDNA B430306N03 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320148 Tuberculist Genomic Region
380863 transmembrane protein 171 Details for - - transmembrane protein 171 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380863 Tuberculist Genomic Region	380916 leucine-rich repeats and calponin homology (CH) domain containing 1 Details for - - leucine-rich repeats and calponin homology (CH) domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380916 Tuberculist Genomic Region
56045 SAM domain and HD domain, 1 Details for RP23-163J20.2 - SAM domain and HD domain, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56045 Tuberculist Genomic Region	56501 E74-like factor 4 (ets domain transcription factor) Details for RP23-260P5.2 - E74-like factor 4 (ets domain transcription factor) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56501 Tuberculist Genomic Region
574428 zinc finger, MYND-type containing 15 Details for DN-491F10.7 - zinc finger, MYND-type containing 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 574428 Tuberculist Genomic Region	621875 RIKEN cDNA A530040E14 gene Details for - - RIKEN cDNA A530040E14 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 621875 Tuberculist Genomic Region
68497 apoptosis resistant E3 ubiquitin protein ligase 1 Details for - - apoptosis resistant E3 ubiquitin protein ligase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68497 Tuberculist Genomic Region	69116 ubiquitin protein ligase E3 component n-recognin 4 Details for - - ubiquitin protein ligase E3 component n-recognin 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69116 Tuberculist Genomic Region
70859 leucine rich repeat containing 63 Details for - - leucine rich repeat containing 63 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70859 Tuberculist Genomic Region	71934 carbonic anhydrase 13 Details for - - carbonic anhydrase 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71934 Tuberculist Genomic Region
71956 ring finger protein 135 Details for RP23-345E8.1 - ring finger protein 135 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71956 Tuberculist Genomic Region	73656 membrane-spanning 4-domains, subfamily A, member 6C Details for - - membrane-spanning 4-domains, subfamily A, member 6C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73656 Tuberculist Genomic Region
75234 ring finger protein 19B Details for RP23-284L6.1 - ring finger protein 19B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75234 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_IRF2_Q6_M01882	0.72	0.00000000000514

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.014	AANAAGRAAA	NA	0.37	CCCCNCCCCYM	SP1_MA0079.2, Klf4_MA0039.2, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$CKROX_Q2_M01175, V$ZFP281_04_M02831, V$KLF7_03_M02773, V$GC_01_M00255, V$MAZ_Q6_M00649, V$MAZR_01_M00491, V$GKLF_02_M01588, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$KLF15_Q2_M01714, V$ZNF219_01_M01122, V$BCL6B_04_M02844, V$MAZ_Q6_01_M02023, V$ZFP740_03_M02834, V$CACD_01_M01113, V$ZFP410_04_M02936, V$SP1SP3_Q4_M01219, V$SP1_01_M00008, V$ETF_Q6_M00695, V$EKLF_Q5_M01874, V$MZF1_01_M00083, Zfp281.2, Klf7.1, Bcl6b.2, Zfp740.1, Zfp410.1, Ascl2.2, Sp4.1, Egr1.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.94	CGGGGA	MZF1_1-4_MA0056.1	1.19	CCGGGGAG	Zfp740.2, Bcl6b.2, Zfp410.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.64	AGGCTA	NA	NA	0.76	GGTAGCAA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-343	0.823529	0.000023

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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