TargetScan_215 megaCluster: 11 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_215	11	0.22	15	0	0.904923	0

Members

Displaying 1 - 32 of 32

14645 glutamate-ammonia ligase (glutamine synthetase) Details for - - glutamate-ammonia ligase (glutamine synthetase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14645 Tuberculist Genomic Region	20744 spermatid perinuclear RNA binding protein Details for RP23-391H10.1 - spermatid perinuclear RNA binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20744 Tuberculist Genomic Region
53332 myotubularin related protein 1 Details for RP23-125F4.1 - myotubularin related protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53332 Tuberculist Genomic Region	100042480 NHS-like 2 Details for RP23-448C18.1 - NHS-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100042480 Tuberculist Genomic Region
109778 biliverdin reductase A Details for RP23-26A12.2 - biliverdin reductase A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109778 Tuberculist Genomic Region	110006 glucuronidase, beta Details for - - glucuronidase, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110006 Tuberculist Genomic Region
11883 arylsulfatase A Details for - - arylsulfatase A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11883 Tuberculist Genomic Region	13194 damage specific DNA binding protein 1 Details for - - damage specific DNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13194 Tuberculist Genomic Region
14194 fumarate hydratase 1 Details for - - fumarate hydratase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14194 Tuberculist Genomic Region	14661 glutamate dehydrogenase 1 Details for - - glutamate dehydrogenase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14661 Tuberculist Genomic Region
15488 hydroxysteroid (17-beta) dehydrogenase 4 Details for - - hydroxysteroid (17-beta) dehydrogenase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15488 Tuberculist Genomic Region	15985 CD79B antigen Details for RP23-418O11.7 - CD79B antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15985 Tuberculist Genomic Region
19684 radixin Details for - - radixin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19684 Tuberculist Genomic Region	20778 scavenger receptor class B, member 1 Details for - - scavenger receptor class B, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20778 Tuberculist Genomic Region
211347 pantothenate kinase 3 Details for RP23-196B5.1 - pantothenate kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211347 Tuberculist Genomic Region	214901 CTF18, chromosome transmission fidelity factor 18 Details for - - CTF18, chromosome transmission fidelity factor 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 214901 Tuberculist Genomic Region
217262 ATP-binding cassette, sub-family A (ABC1), member 9 Details for RP23-328B4.1 - ATP-binding cassette, sub-family A (ABC1), member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217262 Tuberculist Genomic Region	217558 G2/M-phase specific E3 ubiquitin ligase Details for - - G2/M-phase specific E3 ubiquitin ligase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217558 Tuberculist Genomic Region
227298 family with sequence similarity 134, member A Details for - - family with sequence similarity 134, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227298 Tuberculist Genomic Region	231123 HAUS augmin-like complex, subunit 3 Details for - - HAUS augmin-like complex, subunit 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231123 Tuberculist Genomic Region
432940 family with sequence similarity 105, member B Details for - - family with sequence similarity 105, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 432940 Tuberculist Genomic Region	54725 cell adhesion molecule 1 Details for - - cell adhesion molecule 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54725 Tuberculist Genomic Region
56484 forkhead box O3 Details for - - forkhead box O3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56484 Tuberculist Genomic Region	66442 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) Details for RP23-431D4.3 - SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66442 Tuberculist Genomic Region
66868 major facilitator superfamily domain containing 1 Details for - - major facilitator superfamily domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66868 Tuberculist Genomic Region	68520 zinc finger, FYVE domain containing 21 Details for - - zinc finger, FYVE domain containing 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68520 Tuberculist Genomic Region
68877 MAF1 homolog (S. cerevisiae) Details for - - MAF1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68877 Tuberculist Genomic Region	70829 coiled-coil domain containing 93 Details for - - coiled-coil domain containing 93 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70829 Tuberculist Genomic Region
75292 protein kinase D3 Details for - - protein kinase D3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75292 Tuberculist Genomic Region	76687 signal peptidase complex subunit 3 homolog (S. cerevisiae) Details for - - signal peptidase complex subunit 3 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76687 Tuberculist Genomic Region
97541 glutaminyl-tRNA synthetase Details for - - glutaminyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97541 Tuberculist Genomic Region	66455 canopy 4 homolog (zebrafish) Details for - - canopy 4 homolog (zebrafish) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66455 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_GC_01_M00255	1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.004	TTTNTTTTTTMA	NA	0.075	NGGGGGCGGGG	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP4_Q5_M01273, V$ZFP281_01_M01597, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_02_M01303, V$SP1_Q4_01_M00932, V$KLF7_03_M02773, V$UF1H3BETA_Q6_M01068, V$SP1_Q6_01_M00931, V$SP1_03_M02281, V$SP4_03_M02810, V$GC_01_M00255, V$CKROX_Q2_M01175, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$EGR1_Q6_M01873, V$GKLF_02_M01588, V$ZFP281_04_M02831, V$MAZ_Q6_M00649, V$MAZR_01_M00491, V$WT1_Q6_01_M02036, V$ZNF219_01_M01122, V$SP1SP3_Q4_M01219, V$SP1_01_M00008, V$E2F3_Q6_M02089, V$MAZ_Q6_01_M02023, V$CACD_01_M01113, V$SP2_01_M01783, V$BCL6B_04_M02844, V$ZFP740_03_M02834, V$SMAD4_04_M02898, V$KLF15_Q2_M01714, V$RNF96_01_M01199, V$ETF_Q6_M00695, V$CACBINDINGPROTEIN_Q6_M00720, V$EGR_Q6_M00807, V$EKLF_Q5_M01874, V$FKLF_Q5_M01837, V$ZFP410_04_M02936, V$CACCCBINDINGFACTOR_Q6_M00721, V$INSM1_01_M02268, V$WT1_Q6_M01118, Klf7.1, Sp4.1, Egr1.1, Zfp281.2, Bcl6b.2, Zfp740.1, Smad3.1, Zfp410.1, Zif268.1, Zbtb7b.1, Ascl2.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1, SP3_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, KLF13_C2H2_full_monomeric_18_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.15	GGTCGC	NA	1.22	TCGNCGCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.59	GCGTCG	NA	NA	0.61	GNKTCGAG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-3105-3p	0.464286	0.0000543

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