TargetScan_231 megaCluster: 10 Residual: 0.23 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_231	10	0.23	15	0	0.887643	0

Members

Displaying 1 - 28 of 28

104776 aldehyde dehydrogenase family 6, subfamily A1 Details for - - aldehyde dehydrogenase family 6, subfamily A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104776 Tuberculist Genomic Region	110749 chromatin assembly factor 1, subunit B (p60) Details for - - chromatin assembly factor 1, subunit B (p60) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110749 Tuberculist Genomic Region
12028 BCL2-associated X protein Details for - - BCL2-associated X protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12028 Tuberculist Genomic Region	12315 calmodulin 3 Details for - - calmodulin 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12315 Tuberculist Genomic Region
12448 cyclin E2 Details for RP23-343F17.5 - cyclin E2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12448 Tuberculist Genomic Region	12649 checkpoint kinase 1 Details for - - checkpoint kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12649 Tuberculist Genomic Region
15185 histone deacetylase 6 Details for RP23-198C2.1 - histone deacetylase 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15185 Tuberculist Genomic Region	170439 ELOVL family member 6, elongation of long chain fatty acids (yeast) Details for - - ELOVL family member 6, elongation of long chain fatty acids (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170439 Tuberculist Genomic Region
17217 minichromosome maintenance deficient 4 homolog (S. cerevisiae) Details for - - minichromosome maintenance deficient 4 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17217 Tuberculist Genomic Region	18973 polymerase (DNA directed), epsilon Details for - - polymerase (DNA directed), epsilon GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18973 Tuberculist Genomic Region
215387 non-SMC condensin I complex, subunit H Details for - - non-SMC condensin I complex, subunit H GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 215387 Tuberculist Genomic Region	22248 unc-119 homolog (C. elegans) Details for RP23-185A18.16-002 - unc-119 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22248 Tuberculist Genomic Region
227333 diacylglycerol kinase, delta Details for - - diacylglycerol kinase, delta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227333 Tuberculist Genomic Region	230376 HAUS augmin-like complex, subunit 6 Details for RP23-95O1.3 - HAUS augmin-like complex, subunit 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230376 Tuberculist Genomic Region
231866 zinc finger protein 12 Details for - - zinc finger protein 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231866 Tuberculist Genomic Region	236794 solute carrier family 9 (sodium/hydrogen exchanger), member 6 Details for RP23-105E2.4 - solute carrier family 9 (sodium/hydrogen exchanger), member 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236794 Tuberculist Genomic Region
23908 heparan sulfate 2-O-sulfotransferase 1 Details for - - heparan sulfate 2-O-sulfotransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23908 Tuberculist Genomic Region	240064 zinc finger protein 799 Details for - - zinc finger protein 799 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240064 Tuberculist Genomic Region
246102 rotatin Details for - - rotatin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246102 Tuberculist Genomic Region	260409 CDC42 effector protein (Rho GTPase binding) 3 Details for - - CDC42 effector protein (Rho GTPase binding) 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 260409 Tuberculist Genomic Region
50496 E2F transcription factor 6 Details for - - E2F transcription factor 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50496 Tuberculist Genomic Region	60411 centromere protein K Details for - - centromere protein K GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60411 Tuberculist Genomic Region
67036 mitochondrial ribosomal protein L45 Details for RP23-157O10.1 - mitochondrial ribosomal protein L45 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67036 Tuberculist Genomic Region	69305 decapping enzyme, scavenger Details for - - decapping enzyme, scavenger GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69305 Tuberculist Genomic Region
72357 RIKEN cDNA 2210016L21 gene Details for - - RIKEN cDNA 2210016L21 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72357 Tuberculist Genomic Region	98828 cell division cycle 123 Details for RP23-307E15.1 - cell division cycle 123 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98828 Tuberculist Genomic Region
218973 WD repeat and HMG-box DNA binding protein 1 Details for - - WD repeat and HMG-box DNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218973 Tuberculist Genomic Region	235559 topoisomerase (DNA) II binding protein 1 Details for - - topoisomerase (DNA) II binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235559 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
NA

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.019	AAANAAAA	NA	1.4	CCNCCCCNCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_02_M01303, V$MAZ_Q6_01_M02023, V$ZFP281_01_M01597, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$CKROX_Q2_M01175, V$SP1_03_M02281, V$UF1H3BETA_Q6_M01068, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$MAZ_Q6_M00649, V$ZFP281_04_M02831, V$GC_01_M00255, V$ZFP740_03_M02834, V$MAZR_01_M00491, V$KLF7_03_M02773, V$BCL6B_04_M02844, V$ZFP410_04_M02936, V$ZNF219_01_M01122, V$ZBP89_Q4_M01816, V$SMAD4_04_M02898, V$GKLF_02_M01588, V$KLF15_Q2_M01714, V$ETF_Q6_M00695, V$SP1_01_M00008, V$FKLF_Q5_M01837, V$KROX_Q6_M00982, V$SP1SP3_Q4_M01219, V$CACD_01_M01113, V$CACBINDINGPROTEIN_Q6_M00720, V$SP4_03_M02810, V$E2F3_Q6_M02089, V$ASCL2_04_M02841, V$EGR1_Q6_M01873, V$EKLF_Q5_M01874, Zfp281.2, Zfp740.1, Klf7.1, Bcl6b.2, Zfp410.1, Smad3.1, Sp4.1, Ascl2.2, Egr1.1, Sox13.2, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Zfp740_C2H2_DBD_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.38	CGTCCG	MIZF_MA0131.1	1.55	CGCGCANG	Zfp161.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.63	TTGTCG	NA	NA	0.68	NNCCTTTG	mmu-mir-6403	7mer_a1

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-450b-5p	0.55	0.0000097

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