TargetScan_42 megaCluster: 8 Residual: 0.14 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_42	8	0.14	15	0	0.964298	0

Members

Displaying 1 - 24 of 24

100532 RELT-like 1 Details for - - RELT-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100532 Tuberculist Genomic Region	107029 malic enzyme 2, NAD(+)-dependent, mitochondrial Details for - - malic enzyme 2, NAD(+)-dependent, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107029 Tuberculist Genomic Region
11907 arginyltransferase 1 Details for - - arginyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11907 Tuberculist Genomic Region	13666 eukaryotic translation initiation factor 2 alpha kinase 3 Details for - - eukaryotic translation initiation factor 2 alpha kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13666 Tuberculist Genomic Region
15488 hydroxysteroid (17-beta) dehydrogenase 4 Details for - - hydroxysteroid (17-beta) dehydrogenase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15488 Tuberculist Genomic Region	17252 retinol dehydrogenase 11 Details for - - retinol dehydrogenase 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17252 Tuberculist Genomic Region
20405 SH3-domain GRB2-like 1 Details for - - SH3-domain GRB2-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20405 Tuberculist Genomic Region	20822 TROVE domain family, member 2 Details for AL592403.2 - TROVE domain family, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20822 Tuberculist Genomic Region
212514 spindle and centriole associated protein 1 Details for - - spindle and centriole associated protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212514 Tuberculist Genomic Region	216134 pyridoxal (pyridoxine, vitamin B6) kinase Details for - - pyridoxal (pyridoxine, vitamin B6) kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216134 Tuberculist Genomic Region
22156 tuftelin 1 Details for - - tuftelin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22156 Tuberculist Genomic Region	224111 UBX domain protein 7 Details for - - UBX domain protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224111 Tuberculist Genomic Region
321007 serine active site containing 1 Details for - - serine active site containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 321007 Tuberculist Genomic Region	381101 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Details for - - 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381101 Tuberculist Genomic Region
67492 zinc finger, AN1-type domain 4 Details for - - zinc finger, AN1-type domain 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67492 Tuberculist Genomic Region	68259 intraflagellar transport 80 Details for - - intraflagellar transport 80 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68259 Tuberculist Genomic Region
69029 single-pass membrane protein with aspartate rich tail 1 Details for - - single-pass membrane protein with aspartate rich tail 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69029 Tuberculist Genomic Region	72486 ring finger protein 219 Details for - - ring finger protein 219 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72486 Tuberculist Genomic Region
75786 cytoskeleton associated protein 5 Details for RP23-176N9.2 - cytoskeleton associated protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75786 Tuberculist Genomic Region	76044 non-SMC condensin II complex, subunit G2 Details for - - non-SMC condensin II complex, subunit G2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76044 Tuberculist Genomic Region
94181 N-acetylneuraminic acid synthase (sialic acid synthase) Details for RP23-117B19.4 - N-acetylneuraminic acid synthase (sialic acid synthase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 94181 Tuberculist Genomic Region	99167 synovial sarcoma, X breakpoint 2 interacting protein Details for - - synovial sarcoma, X breakpoint 2 interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99167 Tuberculist Genomic Region
56424 STIP1 homology and U-Box containing protein 1 Details for - - STIP1 homology and U-Box containing protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56424 Tuberculist Genomic Region	234865 nucleoporin 133 Details for - - nucleoporin 133 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234865 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_GCM_Q2_M00634	0.333333	0.000023

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0018	TTTTGWTTTTTT	NA	0.094	AGGGGCGGGGC	Klf4_MA0039.2, SP1_MA0079.2, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_02_M01303, V$GKLF_02_M01588, V$BCL6B_04_M02844, V$MAZR_01_M00491, V$SP1_03_M02281, V$SP2_01_M01783, V$SP4_03_M02810, V$SP1_01_M00008, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$SMAD4_04_M02898, V$ZFP410_04_M02936, V$CKROX_Q2_M01175, V$E2F3_Q6_M02089, V$ETF_Q6_M00695, V$EGR1_Q6_M01873, V$MAZ_Q6_M00649, V$MAZ_Q6_01_M02023, V$CACD_01_M01113, V$KROX_Q6_M00982, V$ZBP89_Q4_M01816, V$EGR1_06_M02744, V$ZFP281_04_M02831, V$KLF15_Q2_M01714, V$SP1SP3_Q4_M01219, V$SP4_04_M02914, Klf7.1, Bcl6b.2, Sp4.1, Smad3.1, Zfp410.1, Egr1.1, Zfp281.2, Sp4.2, Zfp740.1, SP4_C2H2_full_monomeric_17_1, KLF13_C2H2_full_monomeric_18_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.62	CGCCGA	NA	1.85	GGCGCCGN	V$E2F2_04_M02846, V$E2F4_04_M02847, E2F2.2, E2F3.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.53	GTCGTC	NA	NA	0.85	GTACATTC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-155	0.666667	0.0000149

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1892	0.5	0.0000391

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