TargetScan_45 megaCluster: 10 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_45	10	0.20	15	0	0.92966	0

Members

Displaying 1 - 33 of 33

103711 pyridoxine 5'-phosphate oxidase Details for RP23-353J21.11-001 - pyridoxine 5'-phosphate oxidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 103711 Tuberculist Genomic Region	104130 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 Details for RP23-333P16.5 - NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104130 Tuberculist Genomic Region
11428 aconitase 1 Details for RP23-9F23.1 - aconitase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11428 Tuberculist Genomic Region	117198 influenza virus NS1A binding protein Details for - - influenza virus NS1A binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 117198 Tuberculist Genomic Region
13360 7-dehydrocholesterol reductase Details for - - 7-dehydrocholesterol reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13360 Tuberculist Genomic Region	13595 phenylalkylamine Ca2+ antagonist (emopamil) binding protein Details for RP23-27I6.10-001 - phenylalkylamine Ca2+ antagonist (emopamil) binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13595 Tuberculist Genomic Region
14873 glutathione S-transferase omega 1 Details for - - glutathione S-transferase omega 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14873 Tuberculist Genomic Region	17449 malate dehydrogenase 1, NAD (soluble) Details for RP23-198N8.1 - malate dehydrogenase 1, NAD (soluble) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17449 Tuberculist Genomic Region
20751 sepiapterin reductase Details for - - sepiapterin reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20751 Tuberculist Genomic Region	213068 transmembrane protein 71 Details for - - transmembrane protein 71 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213068 Tuberculist Genomic Region
21855 translocase of inner mitochondrial membrane 17b Details for RP23-198C2.2 - translocase of inner mitochondrial membrane 17b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21855 Tuberculist Genomic Region	26451 ribosomal protein L27A Details for - - ribosomal protein L27A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26451 Tuberculist Genomic Region
320506 LMBR1 domain containing 2 Details for - - LMBR1 domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320506 Tuberculist Genomic Region	51798 enoyl coenzyme A hydratase 1, peroxisomal Details for - - enoyl coenzyme A hydratase 1, peroxisomal GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 51798 Tuberculist Genomic Region
56298 atlastin GTPase 2 Details for - - atlastin GTPase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56298 Tuberculist Genomic Region	63985 glia maturation factor, beta Details for - - glia maturation factor, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 63985 Tuberculist Genomic Region
64656 mitochondrial ribosomal protein S23 Details for RP23-199A2.5 - mitochondrial ribosomal protein S23 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64656 Tuberculist Genomic Region	67738 peptidylprolyl isomerase D (cyclophilin D) Details for - - peptidylprolyl isomerase D (cyclophilin D) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67738 Tuberculist Genomic Region
67973 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) Details for - - M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67973 Tuberculist Genomic Region	68002 RIKEN cDNA 1110058L19 gene Details for - - RIKEN cDNA 1110058L19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68002 Tuberculist Genomic Region
68477 required for meiotic nuclear division 5 homolog A (S. cerevisiae) Details for - - required for meiotic nuclear division 5 homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68477 Tuberculist Genomic Region	68631 crystallin, lambda 1 Details for - - crystallin, lambda 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68631 Tuberculist Genomic Region
68646 NAD kinase 2, mitochondrial Details for - - NAD kinase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68646 Tuberculist Genomic Region	70561 thioredoxin domain containing 16 Details for - - thioredoxin domain containing 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70561 Tuberculist Genomic Region
72981 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) Details for - - protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72981 Tuberculist Genomic Region	74164 nuclear transcription factor, X-box binding 1 Details for RP23-28I8.5 - nuclear transcription factor, X-box binding 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74164 Tuberculist Genomic Region
75416 NOP14 nucleolar protein Details for - - NOP14 nucleolar protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75416 Tuberculist Genomic Region	107029 malic enzyme 2, NAD(+)-dependent, mitochondrial Details for - - malic enzyme 2, NAD(+)-dependent, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107029 Tuberculist Genomic Region
14790 gene rich cluster, C10 gene Details for - - gene rich cluster, C10 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14790 Tuberculist Genomic Region	69221 RIKEN cDNA 2410006H16 gene Details for - - RIKEN cDNA 2410006H16 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69221 Tuberculist Genomic Region
11545 poly (ADP-ribose) polymerase family, member 1 Details for - - poly (ADP-ribose) polymerase family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11545 Tuberculist Genomic Region	216134 pyridoxal (pyridoxine, vitamin B6) kinase Details for - - pyridoxal (pyridoxine, vitamin B6) kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216134 Tuberculist Genomic Region
16970 lymphoid-restricted membrane protein Details for RP24-216M19.3 - lymphoid-restricted membrane protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16970 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_DAX1_01_M01248	0.625	0.0000468

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000073	TKGAAARAAAA	NA	0.096	AGGKGGGNGGGG	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$GKLF_02_M01588, V$KLF7_03_M02773, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$ZFP281_04_M02831, V$SP1_Q6_M00196, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP1_Q6_01_M00931, V$SP1_02_M01303, V$GC_01_M00255, V$CACD_01_M01113, V$ZFP740_03_M02834, V$CKROX_Q2_M01175, V$SP1SP3_Q4_M01219, V$EKLF_Q5_M01874, V$SP4_03_M02810, V$MAZR_01_M00491, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$MAZ_Q6_M00649, V$UF1H3BETA_Q6_M01068, V$MAZ_Q6_01_M02023, V$SMAD4_04_M02898, V$CACCCBINDINGFACTOR_Q6_M00721, V$SP1_01_M00008, V$ZNF219_01_M01122, V$KLF15_Q2_M01714, V$EGR1_Q6_M01873, V$WT1_Q6_01_M02036, V$EGR1_06_M02744, V$EGR_Q6_M00807, V$E2F3_Q6_M02089, V$FKLF_Q5_M01837, V$WT1_Q6_M01118, V$ASCL2_04_M02841, V$MOVOB_01_M01104, V$EGR2_Q6_M02092, V$BCL6B_04_M02844, V$CACBINDINGPROTEIN_Q6_M00720, V$GLI3_Q5_01_M01657, V$SP2_01_M01783, V$ZNF515_01_M01231, V$MZF1_01_M00083, Klf7.1, Zfp281.2, Zfp740.1, Sp4.1, Smad3.1, Egr1.1, Ascl2.2, Bcl6b.2, Sox13.2, Zif268.1, Zfp410.1, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1, KLF13_C2H2_full_monomeric_18_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.39	CGCGAA	NA	1.61	AACGGCGC	E2F3.1, E2F2.1, E2F2.2, E2F3.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.52	CGTGTG	NA	NA	0.55	ATNGTGTG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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