TargetScan_61 megaCluster: 8 Residual: 0.33

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_61 8 0.33 14 0 0.782647 0.034

Members

Displaying 1 - 28 of 28
17312 interleukin 18 receptor accessory protein

Details for - - interleukin 18 receptor accessory protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16174

Tuberculist Genomic Region

18041 C-type lectin domain family 10, member A

Details for DN-160I24.1 - C-type lectin domain family 10, member A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17312

Tuberculist Genomic Region

18973 nitrogen fixation gene 1 (S. cerevisiae)

Details for RP23-220D12.8 - nitrogen fixation gene 1 (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18041

Tuberculist Genomic Region

20452 polymerase (DNA directed), epsilon

Details for - - polymerase (DNA directed), epsilon

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18973

Tuberculist Genomic Region

20918 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

Details for - - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20452

Tuberculist Genomic Region

216440 eukaryotic translation initiation factor 1

Details for RP23-392I3.1 - eukaryotic translation initiation factor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20918

Tuberculist Genomic Region

216445 amplified in osteosarcoma

Details for - - amplified in osteosarcoma

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 216440

Tuberculist Genomic Region

226151 Rho GTPase activating protein 9

Details for - - Rho GTPase activating protein 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 216445

Tuberculist Genomic Region

229603 family with sequence similarity 178, member A

Details for - - family with sequence similarity 178, member A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226151

Tuberculist Genomic Region

231670 OTU domain containing 7B

Details for - - OTU domain containing 7B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 229603

Tuberculist Genomic Region

26378 F-box protein 21

Details for - - F-box protein 21

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 231670

Tuberculist Genomic Region

327762 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal

Details for - - 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26378

Tuberculist Genomic Region

381280 DNA replication helicase 2 homolog (yeast)

Details for - - DNA replication helicase 2 homolog (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 327762

Tuberculist Genomic Region

53331 Holliday junction recognition protein

Details for - - Holliday junction recognition protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 381280

Tuberculist Genomic Region

66615 syntaxin 7

Details for - - syntaxin 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 53331

Tuberculist Genomic Region

66972 autophagy related 4B, cysteine peptidase

Details for - - autophagy related 4B, cysteine peptidase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66615

Tuberculist Genomic Region

67121 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23

Details for - - solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66972

Tuberculist Genomic Region

68549 microtubule associated serine/threonine kinase-like

Details for - - microtubule associated serine/threonine kinase-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67121

Tuberculist Genomic Region

69270 shugoshin-like 2 (S. pombe)

Details for - - shugoshin-like 2 (S. pombe)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68549

Tuberculist Genomic Region

74016 GINS complex subunit 1 (Psf1 homolog)

Details for RP23-193L22.1 - GINS complex subunit 1 (Psf1 homolog)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69270

Tuberculist Genomic Region

74048 PHD finger protein 19

Details for RP23-9N11.3 - PHD finger protein 19

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74016

Tuberculist Genomic Region

74741 RIKEN cDNA 4632428N05 gene

Details for - - RIKEN cDNA 4632428N05 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74048

Tuberculist Genomic Region

17219 C2 calcium-dependent domain containing 5

Details for - - C2 calcium-dependent domain containing 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74741

Tuberculist Genomic Region

18969 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)

Details for - - minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17219

Tuberculist Genomic Region

239570 polymerase (DNA directed), alpha 2

Details for - - polymerase (DNA directed), alpha 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18969

Tuberculist Genomic Region

70024 tetratricopeptide repeat domain 38

Details for - - tetratricopeptide repeat domain 38

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 239570

Tuberculist Genomic Region

76454 minichromosome maintenance deficient 10 (S. cerevisiae)

Details for RP23-379M5.1 - minichromosome maintenance deficient 10 (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70024

Tuberculist Genomic Region

Details for MNCb-2609 - F-box protein 31

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76454

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
FOXC1_forkhead_DBD_dimeric_13_1 0.392857 0.0000621

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
430 TTTTTAAAAAA NA 12000 KGGSTGGGGNTG V$GC_01_M00255, V$SP1_Q6_01_M00931, V$FKLF_Q5_M01837, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.32 ACGCGC Zfp161.2, Zfp161.1, E2F2.1, E2F3.1 1.42 CGTNCCGC NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.54 TGAGNG NA NA 0.68 TGTCCNSA NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-5130 0.32 0.0000511

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