TargetScan_70 megaCluster: 10 Residual: 0.14 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_70	10	0.14	15	0	0.965691	0

Members

Displaying 1 - 30 of 30

109658 taxilin alpha Details for RP23-151A15.8 - taxilin alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109658 Tuberculist Genomic Region	11534 adenosine kinase Details for - - adenosine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11534 Tuberculist Genomic Region
12499 ectonucleoside triphosphate diphosphohydrolase 5 Details for - - ectonucleoside triphosphate diphosphohydrolase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12499 Tuberculist Genomic Region	15254 histidine triad nucleotide binding protein 1 Details for RP24-84L18.1 - histidine triad nucleotide binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15254 Tuberculist Genomic Region
170762 nucleoporin 155 Details for - - nucleoporin 155 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170762 Tuberculist Genomic Region	17685 mutS homolog 2 (E. coli) Details for - - mutS homolog 2 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17685 Tuberculist Genomic Region
18102 NME/NM23 nucleoside diphosphate kinase 1 Details for RP23-378I13.1 - NME/NM23 nucleoside diphosphate kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18102 Tuberculist Genomic Region	20359 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B Details for - - sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20359 Tuberculist Genomic Region
211488 2-aminoethanethiol (cysteamine) dioxygenase Details for - - 2-aminoethanethiol (cysteamine) dioxygenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211488 Tuberculist Genomic Region	211586 transcription factor Dp 2 Details for - - transcription factor Dp 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211586 Tuberculist Genomic Region
21843 Tia1 cytotoxic granule-associated RNA binding protein-like 1 Details for - - Tia1 cytotoxic granule-associated RNA binding protein-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21843 Tuberculist Genomic Region	225659 centrosomal protein 76 Details for - - centrosomal protein 76 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225659 Tuberculist Genomic Region
236266 Alstrom syndrome 1 Details for - - Alstrom syndrome 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236266 Tuberculist Genomic Region	239743 kelch-like 6 Details for - - kelch-like 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239743 Tuberculist Genomic Region
244962 sorting nexin 14 Details for AC116713.1 - sorting nexin 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244962 Tuberculist Genomic Region	269254 senataxin Details for RP23-426D2.7 - senataxin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269254 Tuberculist Genomic Region
445007 nucleoporin 85 Details for RP23-392H19.11-001 - nucleoporin 85 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 445007 Tuberculist Genomic Region	50883 checkpoint kinase 2 Details for - - checkpoint kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50883 Tuberculist Genomic Region
50995 ubiquitin-like modifier activating enzyme 2 Details for RP23-349I9.1 - ubiquitin-like modifier activating enzyme 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50995 Tuberculist Genomic Region	52163 calcium/calmodulin-dependent protein kinase I Details for - - calcium/calmodulin-dependent protein kinase I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52163 Tuberculist Genomic Region
56459 SUMO1 activating enzyme subunit 1 Details for - - SUMO1 activating enzyme subunit 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56459 Tuberculist Genomic Region	666938 BEN domain containing 4 Details for - - BEN domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 666938 Tuberculist Genomic Region
67163 coiled-coil domain containing 47 Details for RP23-81G14.10-001 - coiled-coil domain containing 47 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67163 Tuberculist Genomic Region	67472 mitochondrial fission regulator 1 Details for - - mitochondrial fission regulator 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67472 Tuberculist Genomic Region
73086 ribosomal protein S6 kinase, polypeptide 5 Details for - - ribosomal protein S6 kinase, polypeptide 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73086 Tuberculist Genomic Region	80905 polymerase (DNA directed), eta (RAD 30 related) Details for - - polymerase (DNA directed), eta (RAD 30 related) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80905 Tuberculist Genomic Region
98711 retinol dehydrogenase 10 (all-trans) Details for - - retinol dehydrogenase 10 (all-trans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98711 Tuberculist Genomic Region	320506 LMBR1 domain containing 2 Details for - - LMBR1 domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320506 Tuberculist Genomic Region
64656 mitochondrial ribosomal protein S23 Details for RP23-199A2.5 - mitochondrial ribosomal protein S23 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64656 Tuberculist Genomic Region	216134 pyridoxal (pyridoxine, vitamin B6) kinase Details for - - pyridoxal (pyridoxine, vitamin B6) kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216134 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ZFP206_01_M01742	0.733333	0.00000111

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
1.9	KGCGCASGCGCA	V$ZFP206_01_M01742, V$NRF1_Q6_M00652, V$USF2_Q6_M00726, Zfp161.1, NRF1_NRF_full_dimeric_12_1	7100	GNGGGGCGGGGC	SP1_MA0079.2, Klf4_MA0039.2, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$GKLF_02_M01588, V$ZFP281_01_M01597, V$CKROX_Q2_M01175, V$SP1_03_M02281, V$KLF7_03_M02773, V$UF1H3BETA_Q6_M01068, V$MAZR_01_M00491, V$GC_01_M00255, V$MAZ_Q6_M00649, V$ZFP281_04_M02831, V$SMAD4_04_M02898, V$E2F3_Q6_M02089, V$SP2_01_M01783, V$SP4_03_M02810, V$BCL6B_04_M02844, V$ZBP89_Q4_M01816, V$CACD_01_M01113, V$KLF15_Q2_M01714, V$SP1SP3_Q4_M01219, V$ZNF219_01_M01122, V$ZFP410_04_M02936, V$ETF_Q6_M00695, V$MAZ_Q6_01_M02023, V$EKLF_Q5_M01874, V$SP1_01_M00008, V$KROX_Q6_M00982, V$FKLF_Q5_M01837, Klf7.1, Zfp281.2, Smad3.1, Sp4.1, Bcl6b.2, Zfp410.1, Egr1.1, Zfp740.1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, KLF13_C2H2_full_monomeric_18_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.55	CCGCGA	NA	1.62	GCCGCGNG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.54	CGTCGG	NA	NA	0.67	GTNGGGTC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-337-5p	0.346154	0.0000137

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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