TargetScan_81 megaCluster: 11 Residual: 0.23 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_81	11	0.23	9	0	0.707713	0.562

Members

Displaying 1 - 38 of 38

104184 bleomycin hydrolase Details for RP23-100P23.3 - bleomycin hydrolase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104184 Tuberculist Genomic Region	11749 annexin A6 Details for - - annexin A6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11749 Tuberculist Genomic Region
12021 BRCA1 associated RING domain 1 Details for - - BRCA1 associated RING domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12021 Tuberculist Genomic Region	13433 DNA methyltransferase (cytosine-5) 1 Details for - - DNA methyltransferase (cytosine-5) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13433 Tuberculist Genomic Region
16413 integrin beta 1 binding protein 1 Details for - - integrin beta 1 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16413 Tuberculist Genomic Region	18452 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide Details for RP23-309E16.6 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18452 Tuberculist Genomic Region
19182 proteasome (prosome, macropain) 26S subunit, ATPase 3 Details for RP23-263H8.1 - proteasome (prosome, macropain) 26S subunit, ATPase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19182 Tuberculist Genomic Region	192156 mevalonate (diphospho) decarboxylase Details for - - mevalonate (diphospho) decarboxylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192156 Tuberculist Genomic Region
213002 interferon induced transmembrane protein 6 Details for - - interferon induced transmembrane protein 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213002 Tuberculist Genomic Region	21881 transketolase Details for - - transketolase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21881 Tuberculist Genomic Region
234736 ring finger and WD repeat domain 3 Details for - - ring finger and WD repeat domain 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234736 Tuberculist Genomic Region	236539 3-phosphoglycerate dehydrogenase Details for - - 3-phosphoglycerate dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236539 Tuberculist Genomic Region
240168 RAS, guanyl releasing protein 3 Details for - - RAS, guanyl releasing protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240168 Tuberculist Genomic Region	54405 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 Details for RP23-43O20.5 - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54405 Tuberculist Genomic Region
58911 sulfatase modifying factor 1 Details for - - sulfatase modifying factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58911 Tuberculist Genomic Region	63913 family with sequence similarity 129, member A Details for - - family with sequence similarity 129, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 63913 Tuberculist Genomic Region
66877 Crn, crooked neck-like 1 (Drosophila) Details for RP23-125A1.4 - Crn, crooked neck-like 1 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66877 Tuberculist Genomic Region	67097 ribosomal protein S10 Details for RP24-535O17.1 - ribosomal protein S10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67097 Tuberculist Genomic Region
67903 GIPC PDZ domain containing family, member 1 Details for - - GIPC PDZ domain containing family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67903 Tuberculist Genomic Region	69125 CCR4-NOT transcription complex, subunit 8 Details for RP23-293I3.1 - CCR4-NOT transcription complex, subunit 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69125 Tuberculist Genomic Region
69263 replication factor C (activator 1) 3 Details for - - replication factor C (activator 1) 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69263 Tuberculist Genomic Region	69399 RIKEN cDNA 1700025G04 gene Details for - - RIKEN cDNA 1700025G04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69399 Tuberculist Genomic Region
69716 thyroid hormone receptor interactor 13 Details for - - thyroid hormone receptor interactor 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69716 Tuberculist Genomic Region	71728 serine/threonine kinase 11 interacting protein Details for - - serine/threonine kinase 11 interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71728 Tuberculist Genomic Region
72674 adiponectin receptor 1 Details for - - adiponectin receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72674 Tuberculist Genomic Region	76263 glutathione S-transferase kappa 1 Details for - - glutathione S-transferase kappa 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76263 Tuberculist Genomic Region
76843 denticleless homolog (Drosophila) Details for - - denticleless homolog (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76843 Tuberculist Genomic Region	80286 tumor suppressor candidate 3 Details for - - tumor suppressor candidate 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80286 Tuberculist Genomic Region
100952 elastin microfibril interfacer 1 Details for - - elastin microfibril interfacer 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100952 Tuberculist Genomic Region	17312 C-type lectin domain family 10, member A Details for DN-160I24.1 - C-type lectin domain family 10, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17312 Tuberculist Genomic Region
218215 ring finger protein 144B Details for - - ring finger protein 144B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218215 Tuberculist Genomic Region	21856 translocase of inner mitochondrial membrane 44 Details for - - translocase of inner mitochondrial membrane 44 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21856 Tuberculist Genomic Region
21898 toll-like receptor 4 Details for RP24-209H15.1 - toll-like receptor 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21898 Tuberculist Genomic Region	22697 zinc finger and SCAN domain containing 21 Details for - - zinc finger and SCAN domain containing 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22697 Tuberculist Genomic Region
245866 intraflagellar transport 52 Details for RP23-335N12.4 - intraflagellar transport 52 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245866 Tuberculist Genomic Region	381062 ER membrane associated RNA degradation Details for - - ER membrane associated RNA degradation GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381062 Tuberculist Genomic Region
56043 aldo-keto reductase family 1, member E1 Details for - - aldo-keto reductase family 1, member E1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56043 Tuberculist Genomic Region	74551 phosphoenolpyruvate carboxykinase 2 (mitochondrial) Details for - - phosphoenolpyruvate carboxykinase 2 (mitochondrial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74551 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
RFX2_RFX_DBD_dimeric_15_1	0.351351	0.00000522

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000032	WWAANAAAAAAA	NA	100000	TTCCTTCTTNC	EWSR1-FLI1_MA0149.1, V$EWSR1FLI1_01_M02252

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.02	CGCNTCCT	NA		NA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.54	AGGCGA	NA	NA	0.59	TCNGNGAT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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