TargetScan_90 megaCluster: 7 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_90	7	0.20	15	0	0.929116	0

Members

Displaying 1 - 36 of 36

14426 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 Details for - - UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14426 Tuberculist Genomic Region	18194 NAD(P) dependent steroid dehydrogenase-like Details for RP23-307G22.4 - NAD(P) dependent steroid dehydrogenase-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18194 Tuberculist Genomic Region
19340 RAB3D, member RAS oncogene family Details for - - RAB3D, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19340 Tuberculist Genomic Region	229285 spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) Details for - - spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229285 Tuberculist Genomic Region
240064 zinc finger protein 799 Details for - - zinc finger protein 799 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240064 Tuberculist Genomic Region	27419 alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) Details for - - alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27419 Tuberculist Genomic Region
54607 suppressor of cytokine signaling 6 Details for - - suppressor of cytokine signaling 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54607 Tuberculist Genomic Region	56335 methyltransferase like 3 Details for - - methyltransferase like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56335 Tuberculist Genomic Region
56520 NME/NM23 nucleoside diphosphate kinase 4 Details for - - NME/NM23 nucleoside diphosphate kinase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56520 Tuberculist Genomic Region	56742 proline/serine-rich coiled-coil 1 Details for RP23-27B23.8 - proline/serine-rich coiled-coil 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56742 Tuberculist Genomic Region
67392 RIKEN cDNA 4833420G17 gene Details for - - RIKEN cDNA 4833420G17 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67392 Tuberculist Genomic Region	74455 NOL1/NOP2/Sun domain family member 6 Details for RP23-303M15.1 - NOL1/NOP2/Sun domain family member 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74455 Tuberculist Genomic Region
11409 acyl-Coenzyme A dehydrogenase, short chain Details for - - acyl-Coenzyme A dehydrogenase, short chain GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11409 Tuberculist Genomic Region	214917 family with sequence similarity 173, member A Details for - - family with sequence similarity 173, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 214917 Tuberculist Genomic Region
223646 nicotinate phosphoribosyltransferase domain containing 1 Details for - - nicotinate phosphoribosyltransferase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223646 Tuberculist Genomic Region	238875 Grb2-binding adaptor, transmembrane Details for - - Grb2-binding adaptor, transmembrane GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 238875 Tuberculist Genomic Region
240066 zinc finger protein 870 Details for - - zinc finger protein 870 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240066 Tuberculist Genomic Region	245867 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 Details for RP23-322G1.5 - protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245867 Tuberculist Genomic Region
26378 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal Details for - - 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26378 Tuberculist Genomic Region	27280 pleckstrin homology-like domain, family A, member 3 Details for - - pleckstrin homology-like domain, family A, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27280 Tuberculist Genomic Region
320782 transmembrane protein 154 Details for - - transmembrane protein 154 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320782 Tuberculist Genomic Region	330216 metallo-beta-lactamase domain containing 1 Details for - - metallo-beta-lactamase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330216 Tuberculist Genomic Region
338354 zinc finger protein 780B Details for - - zinc finger protein 780B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 338354 Tuberculist Genomic Region	52563 CDC23 cell division cycle 23 Details for - - CDC23 cell division cycle 23 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52563 Tuberculist Genomic Region
57279 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 Details for - - solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57279 Tuberculist Genomic Region	66273 adipogenesis associated Mth938 domain containing Details for - - adipogenesis associated Mth938 domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66273 Tuberculist Genomic Region
66615 autophagy related 4B, cysteine peptidase Details for - - autophagy related 4B, cysteine peptidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66615 Tuberculist Genomic Region	66905 perilipin 3 Details for - - perilipin 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66905 Tuberculist Genomic Region
67727 syntaxin 17 Details for RP23-122N18.3 - syntaxin 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67727 Tuberculist Genomic Region	71728 serine/threonine kinase 11 interacting protein Details for - - serine/threonine kinase 11 interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71728 Tuberculist Genomic Region
75578 FGGY carbohydrate kinase domain containing Details for RP23-472I13.1 - FGGY carbohydrate kinase domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75578 Tuberculist Genomic Region	78038 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) Details for - - methylcrotonoyl-Coenzyme A carboxylase 2 (beta) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78038 Tuberculist Genomic Region
66559 methionyl aminopeptidase type 1D (mitochondrial) Details for RP23-419H3.1 - methionyl aminopeptidase type 1D (mitochondrial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66559 Tuberculist Genomic Region	14957 histone cluster 1, H1d Details for mCG_50184 - histone cluster 1, H1d GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14957 Tuberculist Genomic Region
65099 interleukin-1 receptor-associated kinase 1 binding protein 1 Details for - - interleukin-1 receptor-associated kinase 1 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65099 Tuberculist Genomic Region	72154 zinc finger protein 157 Details for - - zinc finger protein 157 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72154 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
Elk1.1	0.388889	0.0000215

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000000076	AAACAAAACAAA	V$FOXP1_01_M00987, V$FOXO1_Q5_M01216	1.1	GCCCCGCCCMCT	SP1_MA0079.2, Klf4_MA0039.2, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$GC_01_M00255, V$UF1H3BETA_Q6_M01068, V$ZFP281_01_M01597, V$GKLF_02_M01588, V$SP4_03_M02810, V$SP1_02_M01303, V$SP2_01_M01783, V$KLF7_03_M02773, V$ZBP89_Q4_M01816, V$CKROX_Q2_M01175, V$MAZR_01_M00491, V$EGR1_Q6_M01873, V$ZNF219_01_M01122, V$MAZ_Q6_01_M02023, V$EGR1_06_M02744, V$ZFP281_04_M02831, V$KROX_Q6_M00982, V$MAZ_Q6_M00649, V$SP1SP3_Q4_M01219, V$ETF_Q6_M00695, V$SP1_01_M00008, V$CACD_01_M01113, V$WT1_Q6_01_M02036, V$ZFP740_03_M02834, V$SMAD4_04_M02898, V$EGR_Q6_M00807, V$E2F3_Q6_M02089, V$EKLF_Q5_M01874, V$CACBINDINGPROTEIN_Q6_M00720, V$BCL6B_04_M02844, V$BTEB3_Q5_M01865, V$GKLF_Q4_M01835, V$FKLF_Q5_M01837, V$ZFP410_04_M02936, Sp4.1, Klf7.1, Egr1.1, Zfp281.2, Zfp740.1, Smad3.1, Bcl6b.2, Zif268.1, Zfp410.1, Ascl2.2, Sox13.2, Sp4.2, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, KLF13_C2H2_full_monomeric_18_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.87	TGGCGG	V$SMAD4_04_M02898, Smad3.1, E2F8_E2F_DBD_dimeric_12_1, YY2_C2H2_full_dimeric_12_1, YY2_C2H2_full_monomeric_11_1	1.07	NCGCTGCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.38	CATTAGNN	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-292-5p	0.258065	0.0000279

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