TargetScan_95 megaCluster: 11 Residual: 0.11 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_95	11	0.11	15	0	0.978584	0

Members

Displaying 1 - 23 of 23

14211 structural maintenance of chromosomes 2 Details for RP23-122I3.3 - structural maintenance of chromosomes 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14211 Tuberculist Genomic Region	18140 ubiquitin-like, containing PHD and RING finger domains, 1 Details for - - ubiquitin-like, containing PHD and RING finger domains, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18140 Tuberculist Genomic Region
19361 RAD51 homolog Details for RP23-15I21.4 - RAD51 homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19361 Tuberculist Genomic Region	19366 RAD54 like (S. cerevisiae) Details for RP23-383D12.1 - RAD54 like (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19366 Tuberculist Genomic Region
209334 Gen homolog 1, endonuclease (Drosophila) Details for - - Gen homolog 1, endonuclease (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209334 Tuberculist Genomic Region	228421 kinesin family member 18A Details for RP23-206C1.1 - kinesin family member 18A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228421 Tuberculist Genomic Region
237211 Fanconi anemia, complementation group B Details for RP23-132J17.2 - Fanconi anemia, complementation group B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237211 Tuberculist Genomic Region	240641 kinesin family member 20B Details for - - kinesin family member 20B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240641 Tuberculist Genomic Region
26934 Rac GTPase-activating protein 1 Details for - - Rac GTPase-activating protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26934 Tuberculist Genomic Region	56452 origin recognition complex, subunit 6 Details for - - origin recognition complex, subunit 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56452 Tuberculist Genomic Region
68298 non-SMC condensin I complex, subunit D2 Details for - - non-SMC condensin I complex, subunit D2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68298 Tuberculist Genomic Region	108671 DnaJ (Hsp40) homolog, subfamily C, member 9 Details for - - DnaJ (Hsp40) homolog, subfamily C, member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108671 Tuberculist Genomic Region
114663 inositol (myo)-1(or 4)-monophosphatase 2 Details for - - inositol (myo)-1(or 4)-monophosphatase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114663 Tuberculist Genomic Region	12531 cell division cycle 25B Details for RP23-387C21.1 - cell division cycle 25B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12531 Tuberculist Genomic Region
14156 flap structure specific endonuclease 1 Details for - - flap structure specific endonuclease 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14156 Tuberculist Genomic Region	19363 RAD51 homolog B Details for - - RAD51 homolog B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19363 Tuberculist Genomic Region
19891 replication protein A2 Details for RP23-442A20.4 - replication protein A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19891 Tuberculist Genomic Region	20014 ribophorin II Details for RP23-163J20.6 - ribophorin II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20014 Tuberculist Genomic Region
381306 cDNA sequence BC055324 Details for - - cDNA sequence BC055324 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381306 Tuberculist Genomic Region	56150 MAD2 mitotic arrest deficient-like 1 Details for - - MAD2 mitotic arrest deficient-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56150 Tuberculist Genomic Region
66194 pyrroline-5-carboxylate reductase-like Details for - - pyrroline-5-carboxylate reductase-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66194 Tuberculist Genomic Region	67141 F-box protein 5 Details for - - F-box protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67141 Tuberculist Genomic Region
66934 DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) Details for RP23-430P1.2 - DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66934 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_E2F_Q6_01_M00920	0.434783	0.000000342

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0031	RKGGGCGGGGC	Klf4_MA0039.2, SP1_MA0079.2, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$GC_01_M00255, V$SP1_Q2_01_M00933, V$SP2_01_M01783, V$KLF7_03_M02773, V$GKLF_02_M01588, V$SP1_02_M01303, V$SP1_03_M02281, V$SP4_03_M02810, V$ZBP89_Q4_M01816, V$CKROX_Q2_M01175, V$MAZ_Q6_01_M02023, V$SMAD4_04_M02898, V$MAZR_01_M00491, V$UF1H3BETA_Q6_M01068, V$E2F3_Q6_M02089, V$KROX_Q6_M00982, V$ZFP281_04_M02831, V$EGR1_06_M02744, V$SP1_01_M00008, V$ZFP281_01_M01597, V$ZFP740_03_M02834, V$EGR1_Q6_M01873, V$MAZ_Q6_M00649, V$FKLF_Q5_M01837, V$BCL6B_04_M02844, V$EGR_Q6_M00807, V$SP1SP3_Q4_M01219, V$ETF_Q6_M00695, V$ZNF219_01_M01122, V$ZFP410_04_M02936, V$SP4_04_M02914, V$WT1_Q6_01_M02036, V$CACD_01_M01113, Klf7.1, Sp4.1, Smad3.1, Egr1.1, Zfp281.2, Zfp740.1, Bcl6b.2, Zfp410.1, Sp4.2, Zif268.1, Klf7.2, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF13_C2H2_full_monomeric_18_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, Zfp740_C2H2_DBD_monomeric_10_1	0.42	AGGAARGGAAGC	V$SPI1_Q5_M02031

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.53	TCGCGG	NA	1.9	TTCGCGGG	Zfp740.2, Smad3.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.89	GTCTGGAT	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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