GO:0004420

hydroxymethylglutaryl-CoA reductase (NADPH) activity

Details: 
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. [EC:1.1.1.34, RHEA:15992]
Evidence Code: 
IEA