Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (15357)

Symbol Product Feature Type Strand Chr
15357 Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase protein-coding 13
Synonyms
HMG-CoAR | Red
GO ID Category Definition Evidence
  • hydroxymethylglutaryl-CoA reductase (NADPH) activity
  • peroxisomal membrane
  • endoplasmic reticulum
  • endoplasmic reticulum membrane
  • lipid metabolic process
  • steroid biosynthetic process
  • cholesterol biosynthetic process
  • ubiquinone metabolic process
  • steroid metabolic process
  • cholesterol metabolic process
  • positive regulation of cell proliferation
  • isoprenoid biosynthetic process
  • visual learning
  • embryo development
  • negative regulation of striated muscle cell apoptotic process
  • positive regulation of cardiac muscle cell apoptotic process
  • coenzyme A metabolic process
  • membrane
  • integral component of membrane
  • sterol biosynthetic process
  • oxidoreductase activity
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
  • positive regulation of stress-activated MAPK cascade
  • hydroxymethylglutaryl-CoA reductase activity
  • protein homodimerization activity
  • negative regulation of apoptotic process
  • intracellular membrane-bounded organelle
  • negative regulation of MAP kinase activity
  • negative regulation of vasodilation
  • positive regulation of skeletal muscle tissue development
  • positive regulation of smooth muscle cell proliferation
  • NADP binding
  • coenzyme binding
  • protein tetramerization
  • oxidation-reduction process
  • negative regulation of wound healing
  • negative regulation of insulin secretion involved in cellular response to glucose stimulus
  • positive regulation of ERK1 and ERK2 cascade
  • NADPH binding
Motif 1 Motif 2 Residual
PITA_26 |
Residual: 
0.35
0.35
PITA_61 |
Residual: 
0.36
0.36
TargetScan_189 |
Residual: 
0.30
0.30
TargetScan_232 |
Residual: 
0.27
0.27
Displaying 1 - 4 of 4
Entrez ID STRINGS Network
STRING
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