PITA_123 megaCluster: 8 Residual: 0.13

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_123 8 0.13 15 0 0.967398 0

Members

Displaying 1 - 23 of 23
100929 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)

Details for - - tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100929

Tuberculist Genomic Region

106326 oxysterol binding protein-like 11

Details for - - oxysterol binding protein-like 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 106326

Tuberculist Genomic Region

12576 cyclin-dependent kinase inhibitor 1B

Details for - - cyclin-dependent kinase inhibitor 1B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12576

Tuberculist Genomic Region

17850 methylmalonyl-Coenzyme A mutase

Details for - - methylmalonyl-Coenzyme A mutase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17850

Tuberculist Genomic Region

19687 replication factor C (activator 1) 1

Details for - - replication factor C (activator 1) 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19687

Tuberculist Genomic Region

20817 serine/arginine-rich protein specific kinase 2

Details for - - serine/arginine-rich protein specific kinase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20817

Tuberculist Genomic Region

226539 aspartyl-tRNA synthetase 2 (mitochondrial)

Details for - - aspartyl-tRNA synthetase 2 (mitochondrial)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226539

Tuberculist Genomic Region

231670 F-box protein 21

Details for - - F-box protein 21

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 231670

Tuberculist Genomic Region

64291 oxysterol binding protein-like 1A

Details for - - oxysterol binding protein-like 1A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 64291

Tuberculist Genomic Region

68964 CTS telomere maintenance complex component 1

Details for RP23-19I2.2 - CTS telomere maintenance complex component 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68964

Tuberculist Genomic Region

74114 carnitine O-octanoyltransferase

Details for - - carnitine O-octanoyltransferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74114

Tuberculist Genomic Region

75415 Rho GTPase activating protein 12

Details for - - Rho GTPase activating protein 12

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75415

Tuberculist Genomic Region

76608 HECT domain containing 3

Details for RP23-419D6.4 - HECT domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76608

Tuberculist Genomic Region

84505 SET domain, bifurcated 1

Details for - - SET domain, bifurcated 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 84505

Tuberculist Genomic Region

100900 HscB iron-sulfur cluster co-chaperone homolog (E. coli)

Details for - - HscB iron-sulfur cluster co-chaperone homolog (E. coli)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100900

Tuberculist Genomic Region

140742 sestrin 1

Details for - - sestrin 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 140742

Tuberculist Genomic Region

170719 oxidation resistance 1

Details for - - oxidation resistance 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170719

Tuberculist Genomic Region

18640 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Details for - - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18640

Tuberculist Genomic Region

18747 protein kinase, cAMP dependent, catalytic, alpha

Details for - - protein kinase, cAMP dependent, catalytic, alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18747

Tuberculist Genomic Region

208194 endo/exonuclease (5'-3'), endonuclease G-like

Details for - - endo/exonuclease (5'-3'), endonuclease G-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 208194

Tuberculist Genomic Region

217473 ankyrin repeat and MYND domain containing 2

Details for - - ankyrin repeat and MYND domain containing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217473

Tuberculist Genomic Region

270076 glutaryl-Coenzyme A dehydrogenase

Details for - - glutaryl-Coenzyme A dehydrogenase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 270076

Tuberculist Genomic Region

79221 histone deacetylase 9

Details for - - histone deacetylase 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 79221

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
GSC2_homeodomain_DBD_monomeric_10_1 0.217391 0.0000366

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.00035 WTWAAAAAYAA NA 10 WTTAAAAWGWTW NA

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.31 CGCCGY NA 1.35 NCGCGCGN

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.55 AATCGT NA NA 0.62 ACGTTYGG NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-431 0.45 0.0000396

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