PITA_181 megaCluster: 3 Residual: 0.11 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_181	3	0.11	9	0	0.685125	0.763

Members

Displaying 1 - 28 of 28

23880 FYN binding protein Details for - - FYN binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23880 Tuberculist Genomic Region	69188 lysine (K)-specific methyltransferase 2E Details for - - lysine (K)-specific methyltransferase 2E GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69188 Tuberculist Genomic Region
75089 UHRF1 (ICBP90) binding protein 1-like Details for - - UHRF1 (ICBP90) binding protein 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75089 Tuberculist Genomic Region	104836 Casitas B-lineage lymphoma-like 1 Details for - - Casitas B-lineage lymphoma-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104836 Tuberculist Genomic Region
109361 RIKEN cDNA D730005E14 gene Details for - - RIKEN cDNA D730005E14 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109361 Tuberculist Genomic Region	109624 caldesmon 1 Details for - - caldesmon 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109624 Tuberculist Genomic Region
11655 aminolevulinic acid synthase 1 Details for - - aminolevulinic acid synthase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11655 Tuberculist Genomic Region	12816 collagen, type XII, alpha 1 Details for - - collagen, type XII, alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12816 Tuberculist Genomic Region
12984 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) Details for - - colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12984 Tuberculist Genomic Region	13654 early growth response 2 Details for - - early growth response 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13654 Tuberculist Genomic Region
14579 GTP binding protein (gene overexpressed in skeletal muscle) Details for RP23-54P14.1 - GTP binding protein (gene overexpressed in skeletal muscle) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14579 Tuberculist Genomic Region	14701 guanine nucleotide binding protein (G protein), gamma 12 Details for - - guanine nucleotide binding protein (G protein), gamma 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14701 Tuberculist Genomic Region
192216 transmembrane protein 47 Details for RP23-382D17.1 - transmembrane protein 47 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192216 Tuberculist Genomic Region	20222 splicing factor 3a, subunit 2 Details for - - splicing factor 3a, subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20222 Tuberculist Genomic Region
229898 guanylate binding protein 5 Details for - - guanylate binding protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229898 Tuberculist Genomic Region	230598 nardilysin, N-arginine dibasic convertase, NRD convertase 1 Details for RP23-188A12.1 - nardilysin, N-arginine dibasic convertase, NRD convertase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230598 Tuberculist Genomic Region
239273 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 Details for - - ATP-binding cassette, sub-family C (CFTR/MRP), member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239273 Tuberculist Genomic Region	387173 microRNA 155 Details for - - microRNA 155 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 387173 Tuberculist Genomic Region
407821 zinc and ring finger 3 Details for RP23-293J16.2 - zinc and ring finger 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 407821 Tuberculist Genomic Region	51902 ring finger protein 24 Details for RP23-387C21.6 - ring finger protein 24 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 51902 Tuberculist Genomic Region
54635 platelet-derived growth factor, C polypeptide Details for - - platelet-derived growth factor, C polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54635 Tuberculist Genomic Region	57261 bromodomain containing 4 Details for RP24-236O3.1 - bromodomain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57261 Tuberculist Genomic Region
67956 SET domain containing (lysine methyltransferase) 8 Details for - - SET domain containing (lysine methyltransferase) 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67956 Tuberculist Genomic Region	70425 casein kinase 1, gamma 3 Details for - - casein kinase 1, gamma 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70425 Tuberculist Genomic Region
71712 DNA-damage regulated autophagy modulator 1 Details for - - DNA-damage regulated autophagy modulator 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71712 Tuberculist Genomic Region	78781 zinc finger CCCH type, antiviral 1 Details for - - zinc finger CCCH type, antiviral 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78781 Tuberculist Genomic Region
93730 leucine zipper transcription factor-like 1 Details for - - leucine zipper transcription factor-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 93730 Tuberculist Genomic Region	14571 glycerol phosphate dehydrogenase 2, mitochondrial Details for - - glycerol phosphate dehydrogenase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14571 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_MAZ_Q6_01_M02023	1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
1.8	GGCGGCGGCKNC	V$ETF_Q6_M00695, V$RNF96_01_M01199	0.019	CTCCCCNCCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$MAZ_Q6_01_M02023, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$SP1_02_M01303, V$SP1_Q6_M00196, V$CKROX_Q2_M01175, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$ZFP281_01_M01597, V$CACBINDINGPROTEIN_Q6_M00720, V$MAZ_Q6_M00649, V$KLF15_Q2_M01714, V$MAZR_01_M00491, V$GC_01_M00255, V$ZNF219_01_M01122, V$ZBP89_Q4_M01816, V$ZFP281_04_M02831, V$KLF7_03_M02773, V$ZFP740_03_M02834, V$ASCL2_04_M02841, V$SMAD4_04_M02898, V$SP1SP3_Q4_M01219, V$ZFP410_04_M02936, V$SP1_01_M00008, V$BCL6B_04_M02844, V$FKLF_Q5_M01837, V$GKLF_02_M01588, V$GKLF_Q4_M01835, V$UF1H3BETA_Q6_M01068, V$BTEB3_Q5_M01865, V$SPZ1_01_M00446, V$SP2_01_M01783, V$CACD_01_M01113, V$FPM315_01_M01587, V$E2F3_Q6_M02089, V$MZF1_01_M00083, V$ETF_Q6_M00695, V$WT1_Q6_M01118, V$SOX14_04_M02901, Zfp281.2, Klf7.1, Ascl2.2, Zfp740.1, Smad3.1, Zfp410.1, Bcl6b.2, Sox13.2, Sp4.1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, KLF16_C2H2_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.3	CCGCGA	NA	1.39	GRCGGCCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.72	ATCNTT	NA	NA	1	ACATNNTT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-675-3p	0.727273	0.00000953

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-883b-5p	0.521739	0.0000199

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