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- ubiquitin-protein ligase activity
- frizzled binding
- plasma membrane
- integral component of plasma membrane
- ubiquitin-dependent protein catabolic process
- zinc ion binding
- membrane
- integral component of membrane
- Wnt signaling pathway
- protein ubiquitination
- ligase activity
- negative regulation of Wnt signaling pathway
- Wnt receptor catabolic process
- metal ion binding
- canonical Wnt signaling pathway
- Wnt signaling pathway, planar cell polarity pathway
- stem cell proliferation
- negative regulation of canonical Wnt signaling pathway
- negative regulation of non-canonical Wnt signaling pathway
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