PITA_197 megaCluster: 2 Residual: 0.21

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_197 2 0.21 15 0 0.910236 0

Members

Displaying 1 - 42 of 42
20963 spleen tyrosine kinase

Details for - - spleen tyrosine kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20963

Tuberculist Genomic Region

74030 Ras and Rab interactor 2

Details for RP23-125A1.3 - Ras and Rab interactor 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74030

Tuberculist Genomic Region

100042498 Mir22 host gene (non-protein coding)

Details for - - Mir22 host gene (non-protein coding)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100042498

Tuberculist Genomic Region

11477 chymotrypsin-like

Details for - - chymotrypsin-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 109660

Tuberculist Genomic Region

15558 activin A receptor, type 1

Details for RP23-100B18.4 - activin A receptor, type 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11477

Tuberculist Genomic Region

17113 5-hydroxytryptamine (serotonin) receptor 2A

Details for - - 5-hydroxytryptamine (serotonin) receptor 2A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15558

Tuberculist Genomic Region

17187 mannose-6-phosphate receptor, cation dependent

Details for - - mannose-6-phosphate receptor, cation dependent

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17113

Tuberculist Genomic Region

18356 Max protein

Details for - - Max protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17187

Tuberculist Genomic Region

20218 olfactory receptor 56

Details for RP23-54N20.6 - olfactory receptor 56

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18356

Tuberculist Genomic Region

22341 KH domain containing, RNA binding, signal transduction associated 1

Details for RP23-151A15.11-002 - KH domain containing, RNA binding, signal transduction associated 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20218

Tuberculist Genomic Region

226089 vascular endothelial growth factor C

Details for - - vascular endothelial growth factor C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22341

Tuberculist Genomic Region

232065 RIKEN cDNA C030046E11 gene

Details for - - RIKEN cDNA C030046E11 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226089

Tuberculist Genomic Region

233033 immunoglobulin kappa variable 8-19

Details for - - immunoglobulin kappa variable 8-19

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 232065

Tuberculist Genomic Region

245536 sterile alpha motif domain containing 4B

Details for - - sterile alpha motif domain containing 4B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 233033

Tuberculist Genomic Region

29813 predicted gene 614

Details for RP23-440J15.1 - predicted gene 614

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245536

Tuberculist Genomic Region

327766 zinc finger protein 385A

Details for - - zinc finger protein 385A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 29813

Tuberculist Genomic Region

433638 transmembrane protein 26

Details for - - transmembrane protein 26

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 327766

Tuberculist Genomic Region

52822 RIKEN cDNA I830077J02 gene

Details for - - RIKEN cDNA I830077J02 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 433638

Tuberculist Genomic Region

54153 RUN and FYVE domain containing 3

Details for - - RUN and FYVE domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52822

Tuberculist Genomic Region

66412 RAS p21 protein activator 4

Details for - - RAS p21 protein activator 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54153

Tuberculist Genomic Region

667214 arrestin domain containing 4

Details for - - arrestin domain containing 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66412

Tuberculist Genomic Region

68267 RIKEN cDNA 9930111J21 gene 1

Details for RP23-269N23.3 - RIKEN cDNA 9930111J21 gene 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 667214

Tuberculist Genomic Region

69581 solute carrier family 25 (mitochondrial carrier, glutamate), member 22

Details for - - solute carrier family 25 (mitochondrial carrier, glutamate), member 22

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68267

Tuberculist Genomic Region

70859 ras homolog gene family, member U

Details for - - ras homolog gene family, member U

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69581

Tuberculist Genomic Region

724064 leucine rich repeat containing 63

Details for - - leucine rich repeat containing 63

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70859

Tuberculist Genomic Region

75234 microRNA 148b

Details for - - microRNA 148b

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 724064

Tuberculist Genomic Region

76199 ring finger protein 19B

Details for RP23-284L6.1 - ring finger protein 19B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75234

Tuberculist Genomic Region

79233 mediator complex subunit 13-like

Details for - - mediator complex subunit 13-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76199

Tuberculist Genomic Region

226517 zinc finger protein 319

Details for - - zinc finger protein 319

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 79233

Tuberculist Genomic Region

229003 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

Details for - - Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226517

Tuberculist Genomic Region

23961 helicase with zinc finger 2, transcriptional coactivator

Details for RP23-401M24.3 - helicase with zinc finger 2, transcriptional coactivator

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 229003

Tuberculist Genomic Region

320404 2'-5' oligoadenylate synthetase 1B

Details for - - 2'-5' oligoadenylate synthetase 1B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 23961

Tuberculist Genomic Region

54483 inositol 1,4,5-trisphosphate 3-kinase B

Details for - - inositol 1,4,5-trisphosphate 3-kinase B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 320404

Tuberculist Genomic Region

71956 Mediterranean fever

Details for - - Mediterranean fever

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54483

Tuberculist Genomic Region

76800 ring finger protein 135

Details for RP23-345E8.1 - ring finger protein 135

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71956

Tuberculist Genomic Region

19124 ubiquitin specific peptidase 42

Details for - - ubiquitin specific peptidase 42

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76800

Tuberculist Genomic Region

20779 protein C receptor, endothelial

Details for RP23-388H13.2 - protein C receptor, endothelial

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19124

Tuberculist Genomic Region

27215 Rous sarcoma oncogene

Details for RP23-169M4.1 - Rous sarcoma oncogene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20779

Tuberculist Genomic Region

64292 5-azacytidine induced gene 2

Details for - - 5-azacytidine induced gene 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 27215

Tuberculist Genomic Region

326623 prostaglandin E synthase

Details for RP23-221O14.6 - prostaglandin E synthase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 64292

Tuberculist Genomic Region

380916 tumor necrosis factor (ligand) superfamily, member 15

Details for - - tumor necrosis factor (ligand) superfamily, member 15

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 326623

Tuberculist Genomic Region

Details for - - leucine-rich repeats and calponin homology (CH) domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 380916

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
V_IRF2_Q6_M01882 0.461538 0.000000272

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.00028 RAAAANAAAAAA NA 0.0023 GGAGGNGSNGGG V$SP1SP3_Q4_M01219, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$WT1_Q6_M01118, Zfp281.2, Zfp740.1, Sp4.1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.03 TCGCCG NA 1.11 GNNCGGCG NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.61 TCNAGCCC NA NA NA NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-466g 0.823529 0.00000113

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-3094 0.416667 0.00000338

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