Acvr1 activin A receptor, type 1 (11477)

Symbol Product Feature Type Strand Chr
11477 Acvr1 activin A receptor, type 1 protein-coding 2
Synonyms
ALK2 | ActR-I | ActRIA | Acvr | Acvrlk2 | Alk-2 | Alk8 | D330013D15Rik | SKR1 | Tsk7L
GO ID Category Definition Evidence
  • G1/S transition of mitotic cell cycle
  • nucleotide binding
  • patterning of blood vessels
  • urogenital system development
  • in utero embryonic development
  • gastrulation with mouth forming second
  • mesoderm formation
  • neural crest cell migration
  • embryonic heart tube morphogenesis
  • mitral valve morphogenesis
  • atrial septum primum morphogenesis
  • protein kinase activity
  • protein serine/threonine kinase activity
  • transmembrane receptor protein serine/threonine kinase activity
  • receptor signaling protein serine/threonine kinase activity
  • transforming growth factor beta-activated receptor activity
  • transforming growth factor beta receptor activity, type I
  • ATP binding
  • integral component of plasma membrane
  • protein phosphorylation
  • transmembrane receptor protein serine/threonine kinase signaling pathway
  • transforming growth factor beta receptor signaling pathway
  • germ cell development
  • determination of left/right symmetry
  • gastrulation
  • mesoderm development
  • heart development
  • embryo development
  • negative regulation of signal transduction
  • positive regulation of pathway-restricted SMAD protein phosphorylation
  • membrane
  • integral component of membrane
  • kinase activity
  • phosphorylation
  • activin receptor activity, type I
  • transferase activity
  • transferase activity, transferring phosphorus-containing groups
  • peptidyl-threonine phosphorylation
  • growth factor binding
  • signal transduction by phosphorylation
  • regulation of ossification
  • positive regulation of bone mineralization
  • BMP signaling pathway
  • activin receptor signaling pathway
  • negative regulation of activin receptor signaling pathway
  • intracellular signal transduction
  • protein homodimerization activity
  • apical part of cell
  • positive regulation of osteoblast differentiation
  • positive regulation of transcription, DNA-templated
  • positive regulation of transcription from RNA polymerase II promoter
  • SMAD binding
  • metal ion binding
  • activin receptor complex
  • activin binding
  • transforming growth factor beta binding
  • smooth muscle cell differentiation
  • pharyngeal system development
  • pathway-restricted SMAD protein phosphorylation
  • cardiac muscle cell fate commitment
  • endocardial cushion cell fate commitment
  • positive regulation of determination of dorsal identity
  • negative regulation of extrinsic apoptotic signaling pathway
Motif 1 Motif 2 Residual
PITA_109 |
Residual: 
0.23
0.23
PITA_188 |
Residual: 
0.19
0.19
PITA_197 |
Residual: 
0.21
0.21
TargetScan_77 |
Residual: 
0.14
0.14
TargetScan_96 |
Residual: 
0.24
0.24
Displaying 1 - 5 of 5
Entrez ID STRINGS Network
STRING
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