PITA_38 megaCluster: 1 Residual: 0.29 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_38	1	0.29	13	0	0.800411	0.01

Members

Displaying 1 - 32 of 32

12977 suppressor of cytokine signaling 3 Details for RP23-268N22.6 - suppressor of cytokine signaling 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12702 Tuberculist Genomic Region	12983 colony stimulating factor 1 (macrophage) Details for - - colony stimulating factor 1 (macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12977 Tuberculist Genomic Region
14191 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Details for - - colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12983 Tuberculist Genomic Region	16001 Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog Details for RP23-125F21.1 - Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14191 Tuberculist Genomic Region
16176 insulin-like growth factor I receptor Details for - - insulin-like growth factor I receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16001 Tuberculist Genomic Region	16477 interleukin 1 beta Details for RP23-384K11.2 - interleukin 1 beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16176 Tuberculist Genomic Region
17872 jun B proto-oncogene Details for - - jun B proto-oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16477 Tuberculist Genomic Region	18033 protein phosphatase 1, regulatory (inhibitor) subunit 15A Details for - - protein phosphatase 1, regulatory (inhibitor) subunit 15A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17872 Tuberculist Genomic Region
18550 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18033 Tuberculist Genomic Region	19157 furin (paired basic amino acid cleaving enzyme) Details for - - furin (paired basic amino acid cleaving enzyme) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18550 Tuberculist Genomic Region
207728 cytohesin 1 Details for RP23-28C17.3 - cytohesin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19157 Tuberculist Genomic Region	208449 phosphodiesterase 2A, cGMP-stimulated Details for - - phosphodiesterase 2A, cGMP-stimulated GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207728 Tuberculist Genomic Region
216799 sphingomyelin synthase 1 Details for - - sphingomyelin synthase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 208449 Tuberculist Genomic Region	217069 NLR family, pyrin domain containing 3 Details for RP23-210M6.4 - NLR family, pyrin domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216799 Tuberculist Genomic Region
21938 tripartite motif-containing 25 Details for RP23-176J13.7 - tripartite motif-containing 25 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217069 Tuberculist Genomic Region	22350 tumor necrosis factor receptor superfamily, member 1b Details for RP23-157J11.1 - tumor necrosis factor receptor superfamily, member 1b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21938 Tuberculist Genomic Region
237887 ezrin Details for - - ezrin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22350 Tuberculist Genomic Region	433926 schlafen 10, pseudogene Details for - - schlafen 10, pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237887 Tuberculist Genomic Region
52398 leucine rich repeat containing 8 family, member B Details for - - leucine rich repeat containing 8 family, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 433926 Tuberculist Genomic Region	60406 septin 11 Details for - - septin 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52398 Tuberculist Genomic Region
666730 sin3 associated polypeptide Details for - - sin3 associated polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60406 Tuberculist Genomic Region	66878 zinc finger, ZZ domain containing 3 pseudogene Details for - - zinc finger, ZZ domain containing 3 pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 666730 Tuberculist Genomic Region
71795 RIO kinase 3 Details for - - RIO kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66878 Tuberculist Genomic Region	72446 phosphatidylinositol transfer protein, cytoplasmic 1 Details for RP23-317F9.8 - phosphatidylinositol transfer protein, cytoplasmic 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71795 Tuberculist Genomic Region
72747 proline rich 5 like Details for RP23-325I3.4 - proline rich 5 like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72446 Tuberculist Genomic Region	78103 tetratricopeptide repeat domain 39C Details for - - tetratricopeptide repeat domain 39C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72747 Tuberculist Genomic Region
100504215 RIKEN cDNA 8430431K14 gene Details for - - RIKEN cDNA 8430431K14 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78103 Tuberculist Genomic Region	21426 predicted gene, 20115 Details for - - predicted gene, 20115 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504215 Tuberculist Genomic Region
65112 transcription factor EC Details for - - transcription factor EC GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21426 Tuberculist Genomic Region	17858 prostate transmembrane protein, androgen induced 1 Details for RP23-412O4.1 - prostate transmembrane protein, androgen induced 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65112 Tuberculist Genomic Region
229694 myxovirus (influenza virus) resistance 2 Details for - - myxovirus (influenza virus) resistance 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17858 Tuberculist Genomic Region	Details for - - expressed sequence AI504432 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229694 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ZEC_01_M01081	0.259259	0.00000911

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
1.5	YCCCCCWCCCCC	SP1_MA0079.2, V$ZFP281_01_M01597, V$ZFP281_04_M02831, V$SP1_03_M02281, V$UF1H3BETA_Q6_M01068, V$SP1_02_M01303, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$ZNF219_01_M01122, V$CKROX_Q2_M01175, V$SP1SP3_Q4_M01219, V$SP1_Q4_01_M00932, V$ZFP740_03_M02834, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$CACBINDINGPROTEIN_Q6_M00720, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$ZBP89_Q4_M01816, V$FKLF_Q5_M01837, V$CACD_01_M01113, V$MAZ_Q6_01_M02023, V$MZF1_02_M00084, V$MOVOB_01_M01104, V$FPM315_01_M01587, V$GC_01_M00255, V$KROX_Q6_M00982, V$GKLF_02_M01588, Zfp281.2, Zfp740.1, Bcl6b.2, Klf7.1, Zfp410.1, Sp4.1, Egr1.1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP3_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1	15	AAAMARAAAGNA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.06	CGCGAC	Zfp161.2, Max.2	1.23	CGCAGCTG

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.75	CCGGCC	NA	NA	0.99	CATGCCNC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-423-5p	0.875	0.00000183

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-331-3p	0.541667	0.00000161

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