Igf1r insulin-like growth factor I receptor (16001) | Macrophage Network Portal

Summary

	Symbol	Product	Feature Type	Strand	Chr
16001	Igf1r	insulin-like growth factor I receptor	protein-coding		7

Synonyms

Synonyms
A330103N21Rik \| CD221 \| D930020L01 \| IGF-1R \| hyft

DB XRef

Ensembl	MGI	VEGA
NA	MGI:96433	NA

GO Terms

GO ID	Category	Definition	Evidence
GO:0000166 GO:0001965 GO:0004672 GO:0004713 GO:0004714 GO:0005010 GO:0005158 GO:0005515 GO:0005520 GO:0005524 GO:0005886 GO:0005901 GO:0006468 GO:0006955 GO:0007169 GO:0007409 GO:0007420 GO:0008544 GO:0009887 GO:0010656 GO:0016020 GO:0016021 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0018108 GO:0030010 GO:0030238 GO:0030335 GO:0030879 GO:0031017 GO:0031175 GO:0031994 GO:0032467 GO:0042802 GO:0043005 GO:0043066 GO:0043231 GO:0043235 GO:0043409 GO:0043410 GO:0043433 GO:0043548 GO:0043559 GO:0043560 GO:0045740 GO:0045840 GO:0046328 GO:0046777 GO:0048009 GO:0048015 GO:0051054 GO:0051262 GO:0051291 GO:0051389 GO:0051897 GO:0051898 GO:0060740 GO:0090031	Function Component Process	nucleotide binding G-protein alpha-subunit binding protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity insulin-like growth factor-activated receptor activity insulin receptor binding protein binding insulin-like growth factor binding ATP binding plasma membrane caveola protein phosphorylation immune response transmembrane receptor protein tyrosine kinase signaling pathway axonogenesis brain development epidermis development organ morphogenesis negative regulation of muscle cell apoptotic process membrane integral component of membrane kinase activity phosphorylation transferase activity transferase activity, transferring phosphorus-containing groups peptidyl-tyrosine phosphorylation establishment of cell polarity male sex determination positive regulation of cell migration mammary gland development exocrine pancreas development neuron projection development insulin-like growth factor I binding positive regulation of cytokinesis identical protein binding neuron projection negative regulation of apoptotic process intracellular membrane-bounded organelle receptor complex negative regulation of MAPK cascade positive regulation of MAPK cascade negative regulation of sequence-specific DNA binding transcription factor activity phosphatidylinositol 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of DNA replication positive regulation of mitosis regulation of JNK cascade protein autophosphorylation insulin-like growth factor receptor signaling pathway phosphatidylinositol-mediated signaling positive regulation of DNA metabolic process protein tetramerization protein heterooligomerization inactivation of MAPKK activity positive regulation of protein kinase B signaling negative regulation of protein kinase B signaling prostate gland epithelium morphogenesis positive regulation of steroid hormone biosynthetic process	IEA ISO IPI IDA IMP IC

Regulatory Modules

	Motif 1	Motif 2	Residual
PITA_38 \| PITA_38 Residual: 0.29			0.29
PITA_73 \| PITA_73 Residual: 0.22			0.22
TargetScan_220 \| TargetScan_220 Residual: 0.30			0.30
TargetScan_49 \| TargetScan_49 Residual: 2.58			2.58

Regulation

Displaying 1 - 4 of 4

Regulator Locus	Interaction	Weight

String Network

Entrez ID	STRINGS Network
STRING

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