TargetScan_104 megaCluster: 10 Residual: 0.17 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_104	10	0.17	15	0	0.948121	0

Members

Displaying 1 - 21 of 21

12189 breast cancer 1 Details for RP23-328K2.8 - breast cancer 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12189 Tuberculist Genomic Region	13361 dihydrofolate reductase Details for - - dihydrofolate reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13361 Tuberculist Genomic Region
14247 Friend leukemia integration 1 Details for - - Friend leukemia integration 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14247 Tuberculist Genomic Region	18105 NAD(P)H dehydrogenase, quinone 2 Details for - - NAD(P)H dehydrogenase, quinone 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18105 Tuberculist Genomic Region
212377 MMS22-like, DNA repair protein Details for - - MMS22-like, DNA repair protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212377 Tuberculist Genomic Region	21917 thymopoietin Details for - - thymopoietin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21917 Tuberculist Genomic Region
231506 lin-54 homolog (C. elegans) Details for - - lin-54 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231506 Tuberculist Genomic Region	237877 ATPase family, AAA domain containing 5 Details for RP23-328O2.1 - ATPase family, AAA domain containing 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237877 Tuberculist Genomic Region
237911 BRCA1 interacting protein C-terminal helicase 1 Details for RP23-36C4.3 - BRCA1 interacting protein C-terminal helicase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237911 Tuberculist Genomic Region	241303 family with sequence similarity 78, member A Details for RP23-55I14.8 - family with sequence similarity 78, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241303 Tuberculist Genomic Region
26406 mitogen-activated protein kinase kinase kinase 3 Details for RP23-81G14.5 - mitogen-activated protein kinase kinase kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26406 Tuberculist Genomic Region	64214 regulator of G-protein signaling 18 Details for - - regulator of G-protein signaling 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64214 Tuberculist Genomic Region
13433 DNA methyltransferase (cytosine-5) 1 Details for - - DNA methyltransferase (cytosine-5) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13433 Tuberculist Genomic Region	20226 seryl-aminoacyl-tRNA synthetase Details for RP23-37G19.1 - seryl-aminoacyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20226 Tuberculist Genomic Region
207474 potassium channel tetramerisation domain containing 12b Details for RP23-106P7.1 - potassium channel tetramerisation domain containing 12b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207474 Tuberculist Genomic Region	235559 topoisomerase (DNA) II binding protein 1 Details for - - topoisomerase (DNA) II binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235559 Tuberculist Genomic Region
241627 WD repeat domain 76 Details for RP23-273B19.3 - WD repeat domain 76 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241627 Tuberculist Genomic Region	52626 CDKN2A interacting protein N-terminal like Details for RP23-263C23.1 - CDKN2A interacting protein N-terminal like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52626 Tuberculist Genomic Region
69226 sorting nexing 24 Details for - - sorting nexing 24 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69226 Tuberculist Genomic Region	70650 zinc finger, CCHC domain containing 8 Details for - - zinc finger, CCHC domain containing 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70650 Tuberculist Genomic Region
78658 non-SMC condensin II complex, subunit D3 Details for - - non-SMC condensin II complex, subunit D3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78658 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
SP1_MA0079.2, V_SP1_03_M02281, V_MAZ_Q6_01_M02023	1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
5.5	AAAAANMAAAA	NA	400	TWTMTTTACAT	V$XFD1_01_M00267, V$FOXL1_04_M02753, V$FOXK1_03_M02752, V$FOXA2_04_M02749, V$TEF_Q6_M00672, Foxl1.1, Foxk1.1, Foxa2.1, FOXB1_forkhead_DBD_monomeric_11_1, FOXB1_forkhead_full_monomeric_9_1, FOXC2_forkhead_DBD_monomeric_12_1, FOXC1_forkhead_DBD_dimeric_13_1, FOXC1_forkhead_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.22	TCGGCG	NA	1.55	GGCGCGAA	V$E2F1_Q6_01_M00940, V$E2F_Q2_M00803, V$E2F1_Q3_01_M00938, V$ZF5_01_M00716, V$E2F_03_M00516, V$E2F_01_M00024, V$E2F1_Q6_M00431, V$E2F_Q6_01_M00920

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.65	AGTATG	NA	NA	0.77	AGCACNCA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-878-5p	0.736842	0.00000157

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-34c	0.105263	0.00000318

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