TargetScan_121 megaCluster: 11 Residual: 0.14

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_121	11	0.14	15	0	0.963554	0

Members

Displaying 1 - 43 of 43

TFBS DB TF

TFs	percTargets	pValue
V_VMYB_02_M00227	0.214286	0.00000346

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.35	AMKRAAANAAAA	NA	24	CCCACCCCNCCC	V$ZFP281_04_M02831, V$SP1SP3_Q4_M01219, V$UF1H3BETA_Q6_M01068, V$ZNF219_01_M01122, V$ZFP281_01_M01597, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$SP1_02_M01303, V$WT1_Q6_M01118, V$SP1_03_M02281, V$MAZ_Q6_01_M02023, V$KROX_Q6_M00982, V$CKROX_Q2_M01175, V$MAZ_Q6_M00649, V$ZBP89_Q4_M01816, V$MAZR_01_M00491, V$EGR1_Q6_M01873, V$SP1_Q6_M00196, V$ZFP740_03_M02834, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$GKLF_02_M01588, V$EGR1_04_M02848, V$KLF7_03_M02773, V$ZNF515_01_M01231, V$MOVOB_01_M01104, V$FKLF_Q5_M01837, V$KLF15_Q2_M01714, V$BCL6B_04_M02844, V$CACD_01_M01113, V$WT1_Q6_01_M02036, Zfp281.2, Zfp740.1, Egr1.2, Klf7.1, Bcl6b.2, Sox13.2, Glis2.1, Ascl2.2, Zfp410.1, Egr1.1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP1_C2H2_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.12	CGCGAA	V$E2F_Q6_M00427, V$E2F1_Q6_M00431, V$E2F1_Q6_01_M00940, V$E2F_01_M00024, V$E2F_Q4_M00426, V$E2F_Q3_M00425, V$E2F4DP1_01_M00738, V$E2F_03_M00516, V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, V$E2F1DP1RB_01_M00740, V$E2F_02_M00050, V$E2F_Q4_01_M00919, V$E2F_Q6_01_M00920	1.24	CCTCGCGA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.44	CGCGAA	NA	NA	0.54	TANGGGTC	mmu-mir-99b-5p, mmu-mir-99a-5p, mmu-mir-100-5p	7mer_a1

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

114143 ATPase, H+ transporting, lysosomal V0 subunit B Details for RP23-133J9.4 - ATPase, H+ transporting, lysosomal V0 subunit B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114143 Tuberculist Genomic Region	11689 arachidonate 5-lipoxygenase Details for - - arachidonate 5-lipoxygenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11689 Tuberculist Genomic Region
11891 RAB27A, member RAS oncogene family Details for - - RAB27A, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11891 Tuberculist Genomic Region	19376 RAB34, member of RAS oncogene family Details for RP23-185A18.5 - RAB34, member of RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19376 Tuberculist Genomic Region
216873 sperm associated antigen 7 Details for DN-183N8.18-002 - sperm associated antigen 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216873 Tuberculist Genomic Region	230098 Rho guanine nucleotide exchange factor (GEF) 39 Details for RP23-195K8.7 - Rho guanine nucleotide exchange factor (GEF) 39 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230098 Tuberculist Genomic Region
26411 mitogen-activated protein kinase kinase kinase kinase 1 Details for - - mitogen-activated protein kinase kinase kinase kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26411 Tuberculist Genomic Region	27360 adducin 3 (gamma) Details for - - adducin 3 (gamma) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27360 Tuberculist Genomic Region
56529 SEC11 homolog A (S. cerevisiae) Details for - - SEC11 homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56529 Tuberculist Genomic Region	69163 mitochondrial ribosomal protein L44 Details for - - mitochondrial ribosomal protein L44 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69163 Tuberculist Genomic Region
70356 suppression of tumorigenicity 13 Details for - - suppression of tumorigenicity 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70356 Tuberculist Genomic Region	74470 centrosomal protein 72 Details for - - centrosomal protein 72 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74470 Tuberculist Genomic Region
75317 PARP1 binding protein Details for - - PARP1 binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75317 Tuberculist Genomic Region	109212 family with sequence similarity 64, member A Details for RP23-207N15.1 - family with sequence similarity 64, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109212 Tuberculist Genomic Region
16174 interleukin 18 receptor accessory protein Details for - - interleukin 18 receptor accessory protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16174 Tuberculist Genomic Region	16906 lamin B1 Details for - - lamin B1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16906 Tuberculist Genomic Region
20737 sialophorin Details for - - sialophorin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20737 Tuberculist Genomic Region	53313 ATPase, Ca++ transporting, ubiquitous Details for RP23-263M10.11-001 - ATPase, Ca++ transporting, ubiquitous GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53313 Tuberculist Genomic Region
66154 transmembrane protein 14C Details for - - transmembrane protein 14C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66154 Tuberculist Genomic Region	68017 FtsJ homolog 2 (E. coli) Details for - - FtsJ homolog 2 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68017 Tuberculist Genomic Region
68603 phosphomevalonate kinase Details for - - phosphomevalonate kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68603 Tuberculist Genomic Region	71853 protein disulfide isomerase associated 6 Details for - - protein disulfide isomerase associated 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71853 Tuberculist Genomic Region
72931 SWI5 recombination repair homolog (yeast) Details for RP23-161B9.6 - SWI5 recombination repair homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72931 Tuberculist Genomic Region	73166 transmembrane 7 superfamily member 2 Details for - - transmembrane 7 superfamily member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73166 Tuberculist Genomic Region
73254 coiled-coil domain containing 18 Details for - - coiled-coil domain containing 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73254 Tuberculist Genomic Region	94092 tripartite motif-containing 16 Details for RP23-428I5.1 - tripartite motif-containing 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 94092 Tuberculist Genomic Region
20196 S100 calcium binding protein A13 Details for - - S100 calcium binding protein A13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20196 Tuberculist Genomic Region	21335 transforming, acidic coiled-coil containing protein 3 Details for - - transforming, acidic coiled-coil containing protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21335 Tuberculist Genomic Region
218581 DEP domain containing 1B Details for - - DEP domain containing 1B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218581 Tuberculist Genomic Region	240055 neuralized homolog 1b (Drosophila) Details for - - neuralized homolog 1b (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240055 Tuberculist Genomic Region
433771 mitochondrial inner membrane organizing system 1 Details for RP23-65B16.4 - mitochondrial inner membrane organizing system 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 433771 Tuberculist Genomic Region	68080 GPN-loop GTPase 3 Details for - - GPN-loop GTPase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68080 Tuberculist Genomic Region
71881 adipocyte plasma membrane associated protein Details for RP23-156P22.2 - adipocyte plasma membrane associated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71881 Tuberculist Genomic Region	99152 anaphase promoting complex subunit 2 Details for RP23-132N23.17-001 - anaphase promoting complex subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99152 Tuberculist Genomic Region
108000 centromere protein F Details for - - centromere protein F GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108000 Tuberculist Genomic Region	17992 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 Details for - - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17992 Tuberculist Genomic Region
19357 RAD21 homolog (S. pombe) Details for - - RAD21 homolog (S. pombe) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19357 Tuberculist Genomic Region	52683 non-SMC condensin II complex, subunit H2 Details for - - non-SMC condensin II complex, subunit H2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52683 Tuberculist Genomic Region
53381 peroxiredoxin 4 Details for RP23-395K13.3 - peroxiredoxin 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53381 Tuberculist Genomic Region	68832 RIKEN cDNA 1110057K04 gene Details for - - RIKEN cDNA 1110057K04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68832 Tuberculist Genomic Region
70415 RIKEN cDNA 2610018G03 gene Details for RP23-245F8.1 - RIKEN cDNA 2610018G03 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70415 Tuberculist Genomic Region	213742 inactive X specific transcripts Details for - - inactive X specific transcripts GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 213742 Tuberculist Genomic Region
70536 glutaminyl-peptide cyclotransferase (glutaminyl cyclase) Details for - - glutaminyl-peptide cyclotransferase (glutaminyl cyclase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70536 Tuberculist Genomic Region

TargetScan_121 megaCluster: 11 Residual: 0.14

Summary

Members

Details for RP23-133J9.4 - ATPase, H+ transporting, lysosomal V0 subunit B

Details for - - arachidonate 5-lipoxygenase

Details for - - RAB27A, member RAS oncogene family

Details for RP23-185A18.5 - RAB34, member of RAS oncogene family

Details for DN-183N8.18-002 - sperm associated antigen 7

Details for RP23-195K8.7 - Rho guanine nucleotide exchange factor (GEF) 39

Details for - - mitogen-activated protein kinase kinase kinase kinase 1

Details for - - adducin 3 (gamma)

Details for - - SEC11 homolog A (S. cerevisiae)

Details for - - mitochondrial ribosomal protein L44

Details for - - suppression of tumorigenicity 13

Details for - - centrosomal protein 72

Details for - - PARP1 binding protein

Details for RP23-207N15.1 - family with sequence similarity 64, member A

Details for - - interleukin 18 receptor accessory protein

Details for - - lamin B1

Details for - - sialophorin

Details for RP23-263M10.11-001 - ATPase, Ca++ transporting, ubiquitous

Details for - - transmembrane protein 14C

Details for - - FtsJ homolog 2 (E. coli)

Details for - - phosphomevalonate kinase

Details for - - protein disulfide isomerase associated 6

Details for RP23-161B9.6 - SWI5 recombination repair homolog (yeast)

Details for - - transmembrane 7 superfamily member 2

Details for - - coiled-coil domain containing 18

Details for RP23-428I5.1 - tripartite motif-containing 16

Details for - - S100 calcium binding protein A13

Details for - - transforming, acidic coiled-coil containing protein 3

Details for - - DEP domain containing 1B

Details for - - neuralized homolog 1b (Drosophila)

Details for RP23-65B16.4 - mitochondrial inner membrane organizing system 1

Details for - - GPN-loop GTPase 3

Details for RP23-156P22.2 - adipocyte plasma membrane associated protein

Details for RP23-132N23.17-001 - anaphase promoting complex subunit 2

Details for - - centromere protein F

Details for - - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4

Details for - - RAD21 homolog (S. pombe)

Details for - - non-SMC condensin II complex, subunit H2

Details for RP23-395K13.3 - peroxiredoxin 4

Details for - - RIKEN cDNA 1110057K04 gene

Details for RP23-245F8.1 - RIKEN cDNA 2610018G03 gene

Details for - - inactive X specific transcripts

Details for - - glutaminyl-peptide cyclotransferase (glutaminyl cyclase)

GO Terms

3p UTR PITA