TargetScan_162 megaCluster: 11 Residual: 0.21 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_162	11	0.21	15	0	0.912767	0

Members

Displaying 1 - 27 of 27

16880 leukemia inhibitory factor receptor Details for - - leukemia inhibitory factor receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16880 Tuberculist Genomic Region	17748 metallothionein 1 Details for - - metallothionein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17748 Tuberculist Genomic Region
19224 prostaglandin-endoperoxide synthase 1 Details for RP23-454A14.3 - prostaglandin-endoperoxide synthase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19224 Tuberculist Genomic Region	19352 RAB geranylgeranyl transferase, b subunit Details for - - RAB geranylgeranyl transferase, b subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19352 Tuberculist Genomic Region
381678 zinc finger, CW type with PWWP domain 1 Details for - - zinc finger, CW type with PWWP domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381678 Tuberculist Genomic Region	68080 GPN-loop GTPase 3 Details for - - GPN-loop GTPase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68080 Tuberculist Genomic Region
71881 adipocyte plasma membrane associated protein Details for RP23-156P22.2 - adipocyte plasma membrane associated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71881 Tuberculist Genomic Region	74205 acyl-CoA synthetase long-chain family member 3 Details for - - acyl-CoA synthetase long-chain family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74205 Tuberculist Genomic Region
98386 lamin B receptor Details for - - lamin B receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98386 Tuberculist Genomic Region	110033 kinesin family member 22 Details for - - kinesin family member 22 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110033 Tuberculist Genomic Region
110391 quinoid dihydropteridine reductase Details for - - quinoid dihydropteridine reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110391 Tuberculist Genomic Region	12237 budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) Details for - - budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12237 Tuberculist Genomic Region
12580 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Details for RP23-320F19.3 - cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12580 Tuberculist Genomic Region	15893 islet cell autoantigen 1 Details for - - islet cell autoantigen 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15893 Tuberculist Genomic Region
16551 kinesin family member 11 Details for - - kinesin family member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16551 Tuberculist Genomic Region	18140 ubiquitin-like, containing PHD and RING finger domains, 1 Details for - - ubiquitin-like, containing PHD and RING finger domains, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18140 Tuberculist Genomic Region
209334 Gen homolog 1, endonuclease (Drosophila) Details for - - Gen homolog 1, endonuclease (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209334 Tuberculist Genomic Region	22142 tubulin, alpha 1A Details for - - tubulin, alpha 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22142 Tuberculist Genomic Region
224171 RIKEN cDNA C330027C09 gene Details for - - RIKEN cDNA C330027C09 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224171 Tuberculist Genomic Region	228421 kinesin family member 18A Details for RP23-206C1.1 - kinesin family member 18A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228421 Tuberculist Genomic Region
240641 kinesin family member 20B Details for - - kinesin family member 20B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240641 Tuberculist Genomic Region	26411 mitogen-activated protein kinase kinase kinase kinase 1 Details for - - mitogen-activated protein kinase kinase kinase kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26411 Tuberculist Genomic Region
54124 CDC28 protein kinase 1b Details for - - CDC28 protein kinase 1b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54124 Tuberculist Genomic Region	68475 Sjogren's syndrome nuclear autoantigen 1 Details for RP23-132N23.16-003 - Sjogren's syndrome nuclear autoantigen 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68475 Tuberculist Genomic Region
78894 acetoacetyl-CoA synthetase Details for - - acetoacetyl-CoA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78894 Tuberculist Genomic Region	78903 Werner helicase interacting protein 1 Details for RP23-427P14.3 - Werner helicase interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78903 Tuberculist Genomic Region
27360 adducin 3 (gamma) Details for - - adducin 3 (gamma) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27360 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
SP1_MA0079.2, V_SP1_03_M02281, KLF16_C2H2_DBD_monomeric_11_1, V_ZFP281_01_M01597, V_SP1_Q2_01_M00933	1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000028	WYTTTTTKTTT	Foxd3_MA0041.1, Srf.2	60	GGRGGCGGGGSN	SP1_MA0079.2, V$SP1_03_M02281, V$SP1_Q6_M00196, V$ZFP281_01_M01597, V$SP1SP3_Q4_M01219, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$ZFP281_04_M02831, V$SP4_Q5_M01273, V$GC_01_M00255, V$SP1_02_M01303, V$MAZ_Q6_01_M02023, V$SP1_Q6_01_M00931, V$SP4_03_M02810, V$UF1H3BETA_Q6_M01068, V$EGR1_Q6_M01873, V$SP1_01_M00008, V$KROX_Q6_M00982, V$BCL6B_04_M02844, V$EGR1_06_M02744, V$SMAD4_04_M02898, V$ZNF219_01_M01122, V$ZFP410_04_M02936, V$RNF96_01_M01199, V$EGR_Q6_M00807, V$ETF_Q6_M00695, V$WT1_Q6_M01118, V$MAZR_01_M00491, V$E2F3_Q6_M02089, V$ZFP740_03_M02834, V$KLF7_03_M02773, Zfp281.2, Sp4.1, Egr1.1, Smad3.1, Bcl6b.2, Zfp410.1, Klf7.1, Zfp740.1, Zif268.1, Ascl2.2, SP3_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.44	TCCGCA	NA	1.83	TCGCGCGA	V$E2F1_Q3_01_M00938, V$E2F_03_M00516, V$E2F_Q6_01_M00920, V$E2F_Q4_01_M00919, V$E2F_01_M00024, V$ZF5_01_M00716

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.66	ATTGGT	NA	NA	0.75	AANGGCNG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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