TargetScan_200 megaCluster: 3 Residual: 0.18 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_200	3	0.18	15	0	0.94441	0

Members

Displaying 1 - 29 of 29

22234 UDP-glucose ceramide glucosyltransferase Details for RP23-57N22.4 - UDP-glucose ceramide glucosyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22234 Tuberculist Genomic Region	56045 SAM domain and HD domain, 1 Details for RP23-163J20.2 - SAM domain and HD domain, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56045 Tuberculist Genomic Region
73656 membrane-spanning 4-domains, subfamily A, member 6C Details for - - membrane-spanning 4-domains, subfamily A, member 6C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73656 Tuberculist Genomic Region	100033459 pyrin domain containing 3 Details for - - pyrin domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100033459 Tuberculist Genomic Region
11603 guanylate binding protein 6 Details for - - guanylate binding protein 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100702 Tuberculist Genomic Region	12370 agrin Details for RP23-139J18.2 - agrin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11603 Tuberculist Genomic Region
15162 caspase 8 Details for - - caspase 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12370 Tuberculist Genomic Region	16197 hemopoietic cell kinase Details for - - hemopoietic cell kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15162 Tuberculist Genomic Region
170759 interleukin 7 receptor Details for - - interleukin 7 receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16197 Tuberculist Genomic Region	18991 ATPase type 13A1 Details for - - ATPase type 13A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170759 Tuberculist Genomic Region
19275 POU domain, class 3, transcription factor 1 Details for RP23-230F2.2 - POU domain, class 3, transcription factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18991 Tuberculist Genomic Region	195522 protein tyrosine phosphatase, receptor type, N Details for - - protein tyrosine phosphatase, receptor type, N GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19275 Tuberculist Genomic Region
20847 zinc finger protein 691 Details for RP23-344D2.5 - zinc finger protein 691 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 195522 Tuberculist Genomic Region	20853 signal transducer and activator of transcription 2 Details for - - signal transducer and activator of transcription 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20847 Tuberculist Genomic Region
216991 staufen (RNA binding protein) homolog 1 (Drosophila) Details for RP23-19L12.1 - staufen (RNA binding protein) homolog 1 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20853 Tuberculist Genomic Region	223693 ArfGAP with dual PH domains 2 Details for RP23-7J19.2 - ArfGAP with dual PH domains 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216991 Tuberculist Genomic Region
231430 transmembrane protein 184b Details for - - transmembrane protein 184b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223693 Tuberculist Genomic Region	231655 cytochrome c oxidase assembly protein 18 Details for - - cytochrome c oxidase assembly protein 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231430 Tuberculist Genomic Region
233977 2'-5' oligoadenylate synthetase-like 1 Details for - - 2'-5' oligoadenylate synthetase-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231655 Tuberculist Genomic Region	24110 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 Details for - - protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233977 Tuberculist Genomic Region
243771 ubiquitin specific peptidase 18 Details for - - ubiquitin specific peptidase 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24110 Tuberculist Genomic Region	26362 poly (ADP-ribose) polymerase family, member 12 Details for - - poly (ADP-ribose) polymerase family, member 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 243771 Tuberculist Genomic Region
30935 AXL receptor tyrosine kinase Details for - - AXL receptor tyrosine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26362 Tuberculist Genomic Region	56738 torsin family 3, member A Details for - - torsin family 3, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30935 Tuberculist Genomic Region
57444 molybdenum cofactor synthesis 1 Details for - - molybdenum cofactor synthesis 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56738 Tuberculist Genomic Region	65107 interferon-stimulated protein Details for - - interferon-stimulated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57444 Tuberculist Genomic Region
70144 low-density lipoprotein receptor-related protein 10 Details for - - low-density lipoprotein receptor-related protein 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65107 Tuberculist Genomic Region	74748 leucine-rich repeats and calponin homology (CH) domain containing 3 Details for - - leucine-rich repeats and calponin homology (CH) domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70144 Tuberculist Genomic Region
Details for - - SLAM family member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74748 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ISGF3G_03_M02771	0.413793	0.00000000000122

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00023	AGTTTCNNTTTY	IRF1_MA0050.1, STAT1_MA0137.1, IRF2_MA0051.1, V$IRF_Q6_M00772, V$IRF1_01_M00062, V$IRF2_Q6_M01882, V$IRF_Q6_01_M00972, V$ISRE_01_M00258, V$IRF2_01_M00063, V$IRF1_Q6_01_M01881, V$ICSBP_Q6_M00699, V$IRF7_01_M00453, V$ISGF3G_03_M02771, V$IRF3_05_M02767, V$IRF1_Q6_M00747, Isgf3g.1, Irf3.1, IRF7_IRF_DBD_dimeric_14_1, IRF8_IRF_full_dimeric_14_1, IRF9_IRF_full_trimeric_15_1, IRF3_IRF_full_trimeric_21_1, IRF4_IRF_full_dimeric_15_1, IRF5_IRF_full_dimeric_14_1, PRDM1_C2H2_full_monomeric-or-dimeric_15_1	1000	ATAAANKNAAAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.04	CGCGGT	NA	1.11	CCGAACGG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.57	GCATCN	NA	NA	0.69	CATCGGGC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-3061-5p	0.4	0.0000301

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