Casp8 caspase 8 (12370)

Symbol Product Feature Type Strand Chr
12370 Casp8 caspase 8 protein-coding 1
Synonyms
CASP-8 | FLICE | MACH | Mch5
GO ID Category Definition Evidence
  • angiogenesis
  • neural tube formation
  • protease binding
  • endopeptidase activity
  • cysteine-type endopeptidase activity
  • tumor necrosis factor receptor binding
  • protein binding
  • nucleus
  • cytoplasm
  • mitochondrion
  • centrosome
  • cytosol
  • proteolysis
  • apoptotic process
  • activation of cysteine-type endopeptidase activity involved in apoptotic process
  • heart development
  • peptidase activity
  • cysteine-type peptidase activity
  • extrinsic apoptotic signaling pathway via death domain receptors
  • hydrolase activity
  • macrophage differentiation
  • Noc1p-Noc2p complex
  • death-inducing signaling complex
  • CD95 death-inducing signaling complex
  • ubiquitin protein ligase binding
  • response to tumor necrosis factor
  • regulation of apoptotic process
  • neuron projection
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • negative regulation of I-kappaB kinase/NF-kappaB signaling
  • protein complex
  • cell body
  • membrane raft
  • response to ethanol
  • positive regulation of macrophage differentiation
  • positive regulation of proteolysis
  • protein heterodimerization activity
  • cardiac muscle tissue development
  • protein heterooligomerization
  • proteolysis involved in cellular protein catabolic process
  • negative regulation of necroptotic process
  • regulation of thymocyte apoptotic process
  • cysteine-type endopeptidase activity involved in apoptotic process
  • apoptotic signaling pathway
  • extrinsic apoptotic signaling pathway
  • execution phase of apoptosis
  • activation of cysteine-type endopeptidase activity
  • hepatocyte apoptotic process
  • ripoptosome
  • regulation of apoptotic signaling pathway
  • positive regulation of extrinsic apoptotic signaling pathway
Motif 1 Motif 2 Residual
PITA_209 |
Residual: 
0.31
0.31
PITA_227 |
Residual: 
0.16
0.16
PITA_49 |
Residual: 
0.18
0.18
TargetScan_200 |
Residual: 
0.18
0.18
TargetScan_69 |
Residual: 
0.16
0.16
Displaying 1 - 5 of 5
Entrez ID STRINGS Network
STRING
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