TargetScan_39 megaCluster: 1 Residual: 0.15 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_39	1	0.15	15	0	0.962997	0

Members

Displaying 1 - 29 of 29

100503374 predicted gene, 17435 Details for - - predicted gene, 17435 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503374 Tuberculist Genomic Region	108078 oxidized low density lipoprotein (lectin-like) receptor 1 Details for - - oxidized low density lipoprotein (lectin-like) receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108078 Tuberculist Genomic Region
11655 aminolevulinic acid synthase 1 Details for - - aminolevulinic acid synthase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11655 Tuberculist Genomic Region	12349 carbonic anhydrase 2 Details for - - carbonic anhydrase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12349 Tuberculist Genomic Region
12702 suppressor of cytokine signaling 3 Details for RP23-268N22.6 - suppressor of cytokine signaling 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12702 Tuberculist Genomic Region	16154 interleukin 10 receptor, alpha Details for - - interleukin 10 receptor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16154 Tuberculist Genomic Region
16193 interleukin 6 Details for - - interleukin 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16193 Tuberculist Genomic Region	17909 myosin X Details for - - myosin X GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17909 Tuberculist Genomic Region
18712 proviral integration site 1 Details for - - proviral integration site 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18712 Tuberculist Genomic Region	207728 phosphodiesterase 2A, cGMP-stimulated Details for - - phosphodiesterase 2A, cGMP-stimulated GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207728 Tuberculist Genomic Region
216799 NLR family, pyrin domain containing 3 Details for RP23-210M6.4 - NLR family, pyrin domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216799 Tuberculist Genomic Region	22350 ezrin Details for - - ezrin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22350 Tuberculist Genomic Region
239273 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 Details for - - ATP-binding cassette, sub-family C (CFTR/MRP), member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239273 Tuberculist Genomic Region	246198 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 Details for RP23-94N18.5 - myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246198 Tuberculist Genomic Region
330122 chemokine (C-X-C motif) ligand 3 Details for - - chemokine (C-X-C motif) ligand 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330122 Tuberculist Genomic Region	407821 zinc and ring finger 3 Details for RP23-293J16.2 - zinc and ring finger 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 407821 Tuberculist Genomic Region
66665 Myb/SANT-like DNA-binding domain containing 3 Details for RP23-320C6.1 - Myb/SANT-like DNA-binding domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66665 Tuberculist Genomic Region	66878 RIO kinase 3 Details for - - RIO kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66878 Tuberculist Genomic Region
72580 zinc finger with UFM1-specific peptidase domain Details for - - zinc finger with UFM1-specific peptidase domain GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72580 Tuberculist Genomic Region	74732 syntaxin 11 Details for - - syntaxin 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74732 Tuberculist Genomic Region
75767 RAB11 family interacting protein 1 (class I) Details for - - RAB11 family interacting protein 1 (class I) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75767 Tuberculist Genomic Region	78781 zinc finger CCCH type, antiviral 1 Details for - - zinc finger CCCH type, antiviral 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78781 Tuberculist Genomic Region
13537 dual specificity phosphatase 2 Details for RP23-206D14.6 - dual specificity phosphatase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13537 Tuberculist Genomic Region	217344 rhomboid 5 homolog 2 (Drosophila) Details for RP23-313J14.3 - rhomboid 5 homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217344 Tuberculist Genomic Region
17858 myxovirus (influenza virus) resistance 2 Details for - - myxovirus (influenza virus) resistance 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17858 Tuberculist Genomic Region	23882 growth arrest and DNA-damage-inducible 45 gamma Details for - - growth arrest and DNA-damage-inducible 45 gamma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23882 Tuberculist Genomic Region
71982 sorting nexin 10 Details for - - sorting nexin 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71982 Tuberculist Genomic Region	14571 glycerol phosphate dehydrogenase 2, mitochondrial Details for - - glycerol phosphate dehydrogenase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14571 Tuberculist Genomic Region
18035 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18035 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1_02_M01303, V_ZFP281_01_M01597, V_SP1_Q2_01_M00933	1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
10	GGKGGGNGGGG	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$ZFP281_04_M02831, V$GKLF_02_M01588, V$CKROX_Q2_M01175, V$SP1_Q4_01_M00932, V$UF1H3BETA_Q6_M01068, V$SP1_Q6_M00196, V$ZBP89_Q4_M01816, V$MAZR_01_M00491, V$SP1_Q6_01_M00931, V$MAZ_Q6_M00649, V$KLF7_03_M02773, V$SP1SP3_Q4_M01219, V$ZNF219_01_M01122, V$CACD_01_M01113, V$SP1_02_M01303, V$GC_01_M00255, V$MAZ_Q6_01_M02023, V$EKLF_Q5_M01874, V$ZFP740_03_M02834, V$EGR_Q6_M00807, V$KROX_Q6_M00982, V$EGR1_Q6_M01873, V$WT1_Q6_M01118, V$SP4_03_M02810, V$CACCCBINDINGFACTOR_Q6_M00721, V$FKLF_Q5_M01837, V$MZF1_01_M00083, V$EGR1_06_M02744, V$CACBINDINGPROTEIN_Q6_M00720, V$ZNF515_01_M01231, V$WT1_Q6_01_M02036, V$SP1_01_M00008, V$KLF15_Q2_M01714, V$MOVOB_01_M01104, V$GLI3_Q5_01_M01657, Zfp281.2, Klf7.1, Zfp740.1, Sp4.1, Egr1.1, Smad3.1, Bcl6b.2, Zif268.1, Sox13.2, Ascl2.2, Egr1.2, Glis2.1, Zfp410.1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, Zfp740_C2H2_DBD_monomeric_10_1, KLF14_C2H2_DBD_monomeric_14_1, Klf12_C2H2_DBD_monomeric_15_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1	130	WTAAAAATAWT	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.18	CGCGNC	Zfp161.2	1.26	TCCCGCGM	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.8	GCCGAG	NA	NA	0.76	GNGTCTAG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-681	0.652174	0.0000484

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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