Cdkn2a cyclin-dependent kinase inhibitor 2A (12578)

Symbol Product Feature Type Strand Chr
12578 Cdkn2a cyclin-dependent kinase inhibitor 2A protein-coding 4
Synonyms
ARF-INK4a | Arf | INK4a-ARF | Ink4a/Arf | MTS1 | Pctr1 | p16 | p16(INK4a) | p16INK4a | p19<ARF> | p19ARF
GO ID Category Definition Evidence
  • cell cycle checkpoint
  • regulation of cyclin-dependent protein serine/threonine kinase activity
  • G1/S transition of mitotic cell cycle
  • protein polyubiquitination
  • granular component
  • negative regulation of cell-matrix adhesion
  • p53 binding
  • DNA binding
  • sequence-specific DNA binding transcription factor activity
  • cyclin-dependent protein serine/threonine kinase inhibitor activity
  • protein binding
  • nucleus
  • nucleoplasm
  • nucleolus
  • cytoplasm
  • mitochondrion
  • transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • rRNA processing
  • negative regulation of protein kinase activity
  • apoptotic process
  • activation of cysteine-type endopeptidase activity involved in apoptotic process
  • cell cycle
  • cell cycle arrest
  • aging
  • cell aging
  • transcription factor binding
  • negative regulation of cell proliferation
  • epidermis development
  • apoptotic mitochondrial changes
  • rRNA transcription
  • response to organonitrogen compound
  • regulation of G2/M transition of mitotic cell cycle
  • regulation of gene expression
  • response to organic cyclic compound
  • nuclear body
  • protein kinase binding
  • negative regulation of cell growth
  • negative regulation of B cell proliferation
  • regulation of protein stability
  • protein destabilization
  • negative regulation of NF-kappaB transcription factor activity
  • negative regulation of immature T cell proliferation in thymus
  • positive regulation of protein sumoylation
  • negative regulation of mammary gland epithelial cell proliferation
  • positive regulation of smooth muscle cell apoptotic process
  • somatic stem cell maintenance
  • senescence-associated heterochromatin focus
  • senescence-associated heterochromatin focus assembly
  • negative regulation of phosphorylation
  • response to drug
  • protein complex
  • positive regulation of DNA damage response, signal transduction by p53 class mediator
  • negative regulation of cyclin-dependent protein serine/threonine kinase activity
  • negative regulation of cell cycle
  • negative regulation of transcription, DNA-templated
  • positive regulation of transcription, DNA-templated
  • positive regulation of transcription from RNA polymerase II promoter
  • regulation of nucleocytoplasmic transport
  • regulation of protein export from nucleus
  • somatic stem cell division
  • protein stabilization
  • NF-kappaB binding
  • positive regulation of sequence-specific DNA binding transcription factor activity
  • negative regulation of ubiquitin-protein ligase activity
  • ubiquitin-protein ligase inhibitor activity
  • positive regulation of apoptotic process involved in mammary gland involution
  • cellular response to hydrogen peroxide
  • protein K63-linked ubiquitination
  • positive regulation of cell cycle arrest
  • cellular senescence
  • replicative senescence
  • MDM2/MDM4 family protein binding
  • regulation of apoptotic DNA fragmentation
  • positive regulation of macrophage apoptotic process
  • positive regulation of cellular senescence
Motif 1 Motif 2 Residual
PITA_30 |
Residual: 
0.32
0.32
PITA_65 |
Residual: 
0.20
0.20
TargetScan_159 |
Residual: 
0.27
0.27
TargetScan_54 |
Residual: 
0.36
0.36
Displaying 1 - 4 of 4
Entrez ID STRINGS Network
STRING
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