GO:0031264

death-inducing signaling complex

Details: 
A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor. [GOC:mtg_apoptosis, PMID:12628743, PMID:12655293, PMID:8521815]
Evidence Code: 
IEA