Rv0135c Transcriptional regulator, TetR family

Rv0135c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0366 with residual 0.53 and bicluster_0567 with residual 0.48.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0366 and 200.00 and 6,500.00 for bicluster_0567 respectively.

These modules are enriched for following go terms: hydrolase activity, acting on ester bond... hydro-lyase activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 119
Gene Target Differential Expression Distance Expression pvalue Type
Bile acid 7-alpha dehydratase BaiE (EC 4.2.1.106)
No 27 0.22 0.765604 CDS
No 3 -0.1 0.922608 Primary.TSS
Muconolactone isomerase (EC 5.3.3.4)
No 19 0.11 0.878197 Antisense.TSS
Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)
No -97 -0.15 0.817496 CDS
Transmembrane transport protein MmpL4
No 17 -0.2 0.686507 Primary.TSS
membrane protein, MmpS family
No -130 -0.3 0.677961 Primary.TSS
No -145 -0.25 0.772594 CDS
Phosphoserine phosphatase (EC 3.1.3.3)
No -20 0.28 0.348933 Primary.TSS
membrane protein, MmpS family
No -33 -0.01 0.987383 Primary.TSS
Similar to methyltransferase domain of sarcosine-dimethylglycine methyltransferase
Repressed -68 -2.24 0.000000000054 CDS
not assigned to any KEGG Pathway.
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.98 U
D3I 3 3 3.83 14.55 I
D3U 3 3 3.83 14.19 U
D5I 9 5 6.00 12.91 I
D5U 17 5 6.00 12.92 U
D7I 18 7 8.14 14.19 I
D7U 19 7 8.14 13.98 U
D14I 4 14 15.63 12.54 I
D14U 4 14 15.63 13.74 U
D17I 3 17 19.15 10.82 I
D17U 3 17 19.15 13.48 U
D21I 4 21 23.23 10.43 I
D21U 4 21 23.23 13.56 U
D24I 3 24 26.60 8.46 I
D24U 3 24 26.60 13.44 U
D28I 4 28 30.61 8.77 I
D28U 4 28 30.61 13.41 U