Rv1353c Transcriptional regulator, TetR family

Rv1353c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0418 with residual 0.49 and bicluster_0511 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 7.60 for bicluster_0418 and 670.00 and 6,900.00 for bicluster_0511 respectively.

These modules are enriched for following go terms: phosphopantetheine binding, modified amino acid binding, amide binding, amino acid binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 221 - 230 of 238
Gene Target Differential Expression Distance Expression pvalue Type
Probable acyl-CoA dehydrogenase FadE29 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrC
Induced -115 0.79 0.00837743 Primary.TSS
POSSIBLE OXIDOREDUCTASE
Induced 62 2.24 5.77e-37 Primary.TSS
ESX-1 secretion system protein (Rv3616c)
No -3 0.45 0.298126 Primary.TSS
Cell filamentation protein Fic
No 9 0.41 0.592327 CDS
Adenylate cyclase (EC 4.6.1.1)
No -126 -0.43 0.0458589 Internal.TSS
Adenylate cyclase (EC 4.6.1.1)
No -66 -0.43 0.0458589 CDS
Septum site-determining protein MinD @ possible CpaE
Repressed 19 -1.6 0.0191357 Primary.TSS
Phosphoserine phosphatase (EC 3.1.3.3)
Repressed -148 -0.96 9.7e-17 Primary.TSS
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)
Repressed -20 -2.53 0 Primary.TSS
No -25 0.09 0.828732 CDS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.53 U
D3I 3 3 3.83 11.57 I
D3U 3 3 3.83 12.19 U
D5I 9 5 6.00 8.02 I
D5U 17 5 6.00 10.51 U
D7I 18 7 8.14 7.58 I
D7U 19 7 8.14 10.54 U
D14I 4 14 15.63 2.57 I
D14U 4 14 15.63 9.74 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 9.50 U
D21I 4 21 23.23 I
D21U 4 21 23.23 8.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 8.86 U
D28I 4 28 30.61 1.11 I
D28U 4 28 30.61 7.94 U