Rv1985c HTH-type transcriptional regulator

Rv1985c (HTH-type transcriptional regulator) is predicted to be co-regulated in modules bicluster_0007 with residual 0.55 and bicluster_0380 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0007 and 0.07 and 0.10 for bicluster_0380 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 21 - 30 of 147
Gene Target Differential Expression Distance Expression pvalue Type
membrane protein, MmpS family
No -25 -0.27 0.377636 Primary.TSS
Phosphoribosyl transferase domain protein
No 52 -0.36 0.339125 Primary.TSS
No 30 -0.52 0.478495 Primary.TSS
Capsule biosynthesis protein CapA
No 57 -0.21 0.490565 Primary.TSS
ATPase
No 51 0.05 0.896467 CDS
Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)
No -77 0.02 0.960727 Primary.TSS
DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
No -2 0.22 0.385095 Primary.TSS
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
No -34 0.11 0.706089 CDS
Acyl-CoA dehydrogenase (EC 1.3.99.3)
No -23 0.19 0.54731 Primary.TSS
Translation elongation factor Tu
No 41 0.11 0.769384 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D28I 4 28 30.61 I
D28U 4 28 30.61 5.77 U
D24I 3 24 26.60 I
D24U 3 24 26.60 5.95 U
D21U 4 21 23.23 6.26 U
D21I 4 21 23.23 2.50 I
D17I 3 17 19.15 I
D17U 3 17 19.15 5.97 U
D14I 4 14 15.63 3.27 I
D14U 4 14 15.63 6.73 U
D7I 18 7 8.14 6.54 I
D7U 19 7 8.14 7.53 U
D5I 9 5 6.00 10.84 I
D5U 17 5 6.00 11.33 U
D3I 3 3 3.83 7.89 I
D3U 3 3 3.83 8.32 U
D0U 27 0 0.00 8.34 U