Module 105 Residual: 0.56

Title Bicluster Model Residual Score
bicluster_0105 v02 0.56 -8.35
Displaying 1 - 16 of 16
Rv0050 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

Details for Rv0050 - Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

GO Terms: GO:0008955, GO:0008658, GO:0030288, GO:0052572, GO:0071456

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0050

Tuberculist Genomic Region

Rv0051 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

Details for Rv0051 - Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

GO Terms: NA

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0051

Tuberculist Genomic Region

Rv0380c probable RNA methyltransferase

Details for Rv0380c - probable RNA methyltransferase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.29 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0380c

Tuberculist Genomic Region

Rv0486 Glycosyltransferase MshA involved in mycothiol biosynthesis (EC 2.4.1.-)
Rv0562 Octaprenyl-diphosphate synthase (EC 2.5.1.-) / Dimethylallyltransferase (EC 2.5.1.1) / Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) / Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29)

Details for Rv0562 - Octaprenyl-diphosphate synthase (EC 2.5.1.-) / Dimethylallyltransferase (EC 2.5.1.1) / Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) / Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29)

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Cysteine and methionine metabolism, Terpenoid backbone biosynthesis, Carotenoid biosynthesis, Terpenoid backbone biosynthesis, Tryptophan metabolism, gamma-Hexachlorocyclohexane degradation, Ubiquinone and other terpenoid-quinone biosynthesis, Terpenoid backbone biosynthesis, Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.16 | In vivo Essential: NA

Go to Gene Page: Rv0562

Tuberculist Genomic Region

Rv1298 LSU ribosomal protein L31p

Details for Rv1298 - LSU ribosomal protein L31p

GO Terms: GO:0006412, GO:0005622, GO:0005840, GO:0003735, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.05 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1298

Tuberculist Genomic Region

Rv1299 Peptide chain release factor 1

Details for Rv1299 - Peptide chain release factor 1

GO Terms: GO:0006415, GO:0003747, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv1299

Tuberculist Genomic Region

Rv1300 Methylase of polypeptide chain release factors

Details for Rv1300 - Methylase of polypeptide chain release factors

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv1300

Tuberculist Genomic Region

Rv1301 \YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA\\\""

Details for Rv1301 - \YrdC/Sua5 family protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA\\\""

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.11 | In vivo Essential: NA

Go to Gene Page: Rv1301

Tuberculist Genomic Region

Rv1333 possible hydrolase

Details for Rv1333 - possible hydrolase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: 0.34

Go to Gene Page: Rv1333

Tuberculist Genomic Region

Rv1334 Mec+

Details for Rv1334 - Mec+

GO Terms: GO:0008235, GO:0008270, GO:0019344

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1334

Tuberculist Genomic Region

Rv1335 9.5 kDa culture filtrate antigen Cfp10A

Details for Rv1335 - 9.5 kDa culture filtrate antigen Cfp10A

GO Terms: GO:0019344, GO:0043234

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1335

Tuberculist Genomic Region

Rv1336 Cysteine synthase B (EC 2.5.1.47)

Details for Rv1336 - Cysteine synthase B (EC 2.5.1.47)

GO Terms: GO:0004124, GO:0030170, GO:0033847, GO:0042803, GO:0043234

PATRIC Pathways: Cysteine and methionine metabolism, Sulfur metabolism

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1336

Tuberculist Genomic Region

Rv1337 Rhomboid membrane family protein

Details for Rv1337 - Rhomboid membrane family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1337

Tuberculist Genomic Region

Rv1699 CTP synthase (EC 6.3.4.2)

Details for Rv1699 - CTP synthase (EC 6.3.4.2)

GO Terms: GO:0003883, GO:0005886, GO:0040007

PATRIC Pathways: Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1699

Tuberculist Genomic Region

Rv2868c 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1)

Details for Rv2868c - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1)

GO Terms: GO:0046429, GO:0005886

PATRIC Pathways: Terpenoid backbone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2868c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 3200 e-value: 5800
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 26 of 26
GO:0008955 |

peptidoglycan glycosyltransferase activity

GO:0008658 |

penicillin binding

GO:0030288 |

outer membrane-bounded periplasmic space

GO:0052572 |

response to host immune response

GO:0071456 |

cellular response to hypoxia

GO:0008375 |

acetylglucosaminyltransferase activity

GO:0010125 |

mycothiol biosynthetic process

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0006412 |

translation

GO:0005622 |

intracellular

GO:0005840 |

ribosome

GO:0003735 |

structural constituent of ribosome

GO:0006415 |

translational termination

GO:0003747 |

translation release factor activity

GO:0008235 |

metalloexopeptidase activity

GO:0008270 |

zinc ion binding

GO:0019344 |

cysteine biosynthetic process

GO:0043234 |

protein complex

GO:0004124 |

cysteine synthase activity

GO:0030170 |

pyridoxal phosphate binding

GO:0033847 |

O-phosphoserine sulfhydrylase activity

GO:0042803 |

protein homodimerization activity

GO:0003883 |

CTP synthase activity

GO:0046429 |

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity