P9WPD1 clpB, Rv0384c, MTV036.19c

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WPD1 CLPB_MYCTU
ClpB protein
MTV036.19c Chaperone protein ClpB 9634230, 11567012 clpB clpB, Rv0384c, MTV036.19c
Domain InterPro Pfam ProDom Region Similarity SUPFAM
The N-terminal domain probably functions as a substrate-discriminating domain, recruiting aggregated proteins to the ClpB hexamer and/or stabilizing bound proteins. The NBD2 domain is responsible for oligomerization, whereas the NBD1 domain stabilizes the hexamer probably in an ATP-dependent manner. The movement of the coiled-coil domain is essential for ClpB ability to rescue proteins from an aggregated state, probably by pulling apart large aggregated proteins, which are bound between the coiled-coils motifs of adjacent ClpB subunits in the functional hexamer (By similarity). PF00004, PF07724, PF02861, PF10431 Belongs to the ClpA/ClpB family. SSF52540
Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.1780.10, 3.40.50.300, PF00004, PF07724, PF02861, PF10431 PR00300, PS00870, PS00871 SM00382, SM01086, SSF52540
PDB Protein Model Portal
EC number KEGG KO UniPathway
HOGENOM KEGG KO OMA OrthoDB