P9WKF5 adk, Rv0733, MTV041.07

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WKF5 KAD_MYCTU
Adenylate kinase (EC 2.7.4.3)
MTV041.07 Adenylate kinase (AK) (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) 9634230, 10398370, 20066036, 14705932, 16672241 adk adk, Rv0733, MTV041.07
Binding Site Subcellular location
31 31 AMP., 36 36 AMP., 92 92 AMP., 127 127 ATP., 129 129 AMP., 140 140 AMP., 166 166 ATP, via carbonyl oxygen. Cytoplasm.
Domain InterPro Pfam ProDom Region Similarity SUPFAM
Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. The LID domain is a solvent-exposed domain that is much shorter in Mycobacterium than in many other bacteria like E.coli. Belongs to the adenylate kinase family. SSF52540
Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
3.40.50.300, MF_00235, PR00094, PS00113 SSF52540
PDB Protein Model Portal
HOGENOM KEGG KO OMA OrthoDB