P9WGI1 sigA, mysA, rpoD, rpoV, Rv2703, MTCY05A6.24

Summary

Source: Uniprot proteome:up000001584

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WGI1 SIGA_MYCTU
Rv2703
RNA polymerase sigma factor SigB
 MTCY05A6.24 RNA polymerase sigma factor SigA (Sigma-A) 7489918, 7644534, 9634230, 9882660, 10027986, 11929527, 12354223, 11880648, 19099550, 20729364, 22570422, 23548911, 23605043 sigA sigA, mysA, rpoD, rpoV, Rv2703, MTCY05A6.24

Last update: 06/10/2014

Structure Details

Subcellular location
Cytoplasm (Potential).

Domain/Family Details

Domain InterPro Pfam ProDom Region Similarity SUPFAM
The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA (By similarity). PF00140, PF04542, PF04539, PF04545 Belongs to the sigma-70 factor family. RpoD/SigA subfamily. SSF88659, SSF88946

Domain/Family DBs

Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.10.10, MF_00963, PF00140, PF04542, PF04539, PF04545 PR00046, PS00715, PS00716 SSF88659, SSF88946

SSGCID Target Details

SSGCID ID

3D Details

PDB Protein Model Portal

Pathway Details

EC number KEGG KO UniPathway

Phylogenetic

HOGENOM KEGG KO OMA OrthoDB