Publications
Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance." The Journal of Infectious Diseases. 2019;219:1554-1558.
"TB vaccines; promoting rapid and durable protection in the lung." Curr. Opin. Immunol.. 2015;35:55-62.
"Systems proteomics approaches to study bacterial pathogens: application to Mycobacterium tuberculosis." Curr. Opin. Microbiol.. 2017;39:64-72.
"Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose." PLoS Genet.. 2017;13(12):e1007131.
"Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination." Cell Host Microbe. 2018;24(3):439-446.e4.
"Going beyond gamma for TB protection." Nat Microbiol. 2018;3(11):1194-1195.
"BCG-induced T cells shape Mycobacterium tuberculosis infection before reducing the bacterial burden." bioRxiv. 2019.
"Cutting Edge: Bacillus Calmette–Guérin–Induced T Cells Shape Mycobacterium tuberculosis Infection before Reducing the Bacterial Burden." The Journal of Immunology. 2019;203:807-812.
"Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection." Immunity. 2015;43(6):1125-36.
"Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome." Front Immunol. 2019;10:527.
"Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine." Nat. Med.. 2018;24(2):130-143.
"Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo." Cell Host Microbe. 2016;20(2):250-8.
"Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis." Nat Microbiol. 2020.
"Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis." PLoS Comput. Biol.. 2015;11(11):e1004543.
"Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis." mBio. 2019;10(6).
"The DNA-binding network of Mycobacterium tuberculosis." Nat Commun. 2015;6:5829.
"ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis." J. Exp. Med.. 2015;212(5):715-28.
"Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis." Cell Host Microbe. 2017;21(6):695-706.e5.
"Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection." PLoS Pathog. 2020;16(7):e1008655.
"Elucidation of host-pathogen protein-protein interactions to uncover mechanisms of host cell rewiring." Curr. Opin. Microbiol.. 2017;39:7-15.
"Genetic Diversity in Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease." Annu Rev Genet. 2020.
"Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation." Molecular Systems Biology. 2019;15:e8584.
"Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis." Cell Rep. 2020;31(4):107577.
"Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis." Nat Microbiol. 2016;1(8):16078.
"A high-resolution network model for global gene regulation in Mycobacterium tuberculosis." Nucleic Acids Res.. 2014;42(18):11291-303.
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