Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine. {ECO:0000256|SAAS:SAAS00020866}.; The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. {ECO:0000256|SAAS:SAAS00054021}. |
(L) COG266 | Formamidopyrimidine-DNA glycosylase |
(3.2.2.23, 4.2.99.18) DNA-formamidopyrimidine glycosylase., (3.2.2.23, 4.2.99.18) DNA-(apurinic or apyrimidinic site) lyase. |
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