DVU2981 DVU2981 2-isopropylmalate synthase

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Desulfovibrio vulgaris Hildenborough

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
DVU2981 DVU2981 leuA leuA, DVU2981 2-isopropylmalate synthase 2-isopropylmalate synthase (EC 2.3.3.13) (Alpha-IPM synthase) (Alpha-isopropylmalate synthase) 3087841 3089370 + 15077118

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG OrthoDB
Q726X5 2796295 YP_012192.1; 46581384 208494 AAS97452 IPR013709, IPR002034, IPR013785, IPR005671, IPR000891 COG0119 EOG6CGCF3

Mutations

Transposon mutants

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families
Acetyl-CoA + 3-methyl-2-oxobutanoate + H(2)O = (2S)-2-isopropylmalate + CoA. {ECO:0000256|HAMAP-Rule:MF_01025, ECO:0000256|SAAS:SAAS00172740}. (E) COG119 | Isopropylmalate/homocitrate/citramalate synthases (2.3.3.13, 4.1.3.12) 2-isopropylmalate synthase., (2.3.3.13, 4.1.3.12) Transferred entry: 2.3.3.13. Alpha-IPM synthase/homocitrate synthase family, LeuA type 1 subfamily

Essentiality

WT.MOLS4 WT.MOLS4_NO3 WT.MOYLS4.1 WT.MOYLS4.2
0.59 0.01 1.06 1.22

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
46581384 YP_012192.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
DVU2981

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