DVU3256 DVU3256 Formamidopyrimidine-DNA glycosylase

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Desulfovibrio vulgaris Hildenborough

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
DVU3256 DVU3256 mutM mutM, fpg, DVU3256 Formamidopyrimidine-DNA glycosylase Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (EC 3.2.2.23) (DNA-(apurinic or apyrimidinic site) lyase MutM) (AP lyase MutM) (EC 4.2.99.18) 3428191 3429288 + 15077118

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG OrthoDB
Q726D5 2793859 YP_012466.1; 46581658 208780 AAS97726 IPR015886, IPR015887, IPR012319, IPR020629, IPR010979, IPR000214, IPR010663 COG0266 EOG6QP131

Mutations

Transposon mutants

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families
Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine. {ECO:0000255|HAMAP-Rule:MF_00103}.; The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. {ECO:0000255|HAMAP-Rule:MF_00103}. (L) COG266 | Formamidopyrimidine-DNA glycosylase (3.2.2.23, 4.2.99.18) DNA-formamidopyrimidine glycosylase., (3.2.2.23, 4.2.99.18) DNA-(apurinic or apyrimidinic site) lyase. FPG family

Essentiality

WT.MOLS4 WT.MOLS4_NO3 WT.MOYLS4.1 WT.MOYLS4.2
1.47 0.04 1.87 1.94

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
46581658 YP_012466.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
DVU3256

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