MMP0026 MMP0026 DNA-directed DNA polymerase II large subunit (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP0026 MMP0026 DP2 polC, MMP0026 DNA-directed DNA polymerase II large subunit (NCBI) DNA polymerase II large subunit (Pol II) (EC 2.7.7.7) 36651 33256 - 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0025 0.31
mmp-bicluster_0041 0.48
mmp-bicluster_0092 0.41

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG
Q6M191 2762226 NP_987146.1; 45357589 532197 CAF29582 IPR004475, IPR016033 COG1933

Mutations

Line Position Effect Impact Class Percent Frequency Sample Title
HE2 35 655 NON_SYNONYMOUS_CODING MISSENSE 72 TG_HE2 BX950229-MMP0026-35655-TG_HE2
HS3 35 597 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HS3_45 BX950229-MMP0026-35597-EG_HS3_45
HS3 35 597 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HS3_15 BX950229-MMP0026-35597-EG_HS3_15
HS3 35 597 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HS3_76 BX950229-MMP0026-35597-EG_HS3_76

Transposon mutants

Title Insert TAG Module
MMP0026

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families TIGR Roles
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). {ECO:0000255|HAMAP-Rule:MF_00324}.; Degradation of single-stranded DNA. It acts progressively in a 3'- to 5'-direction, releasing nucleoside 5'-phosphates. {ECO:0000255|HAMAP-Rule:MF_00324}. (L) COG1933 | Archaeal DNA polymerase II, large subunit (2.7.7.7) DNA-directed DNA polymerase. Archaeal DNA polymerase II family DNA metabolism:DNA replication, recombination, and repair

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
3 2 1 1 14 1 1 1 2 13

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45357589 NP_987146.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP0026

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