MMP0956 MMP0956 DNA topoisomerase I (NCBI) | Syntrophy Portal

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Methanococcus maripaludis S2

Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MMP0956	MMP0956	topA	topA, MMP0956	DNA topoisomerase I (NCBI)	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)	943765	946236	+	15466049

XReference

Uniprot	NCBI Gene	NCBI Protein	GI Number	MicrobesOnline	EnsemblBacteria	InterPro	EggNOG
Q6LYN4	2762158	NP_988076.1;	45358519	533151	CAF30512	IPR000380, IPR003601, IPR013497, IPR013824, IPR013826, IPR023405, IPR003602, IPR013498, IPR005739, IPR028612, IPR006171	COG0551

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	Sample	Title

Transposon mutants

Title	Insert	TAG Module
MMP0956

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	COG	EC Description	Protein families	TIGR Roles
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining. {ECO:0000256\|HAMAP-Rule:MF_00952}.	(L) COG550 \| Topoisomerase IA	(5.99.1.2) DNA topoisomerase.	Type IA topoisomerase family	DNA metabolism:DNA replication, recombination, and repair

Essentiality

L1.Cm.T1	L1.Cm.T2	L1.cN.T1	L1.cN.T2	L1.T0	L2.Cm.T1	L2.Cm.T2	L2.cN.T1	L2.cN.T2	L2.T0
7	2	2	1	34	8	1	4	1	21

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains
45358519	NP_988076.1	Run

GO Terms

GO:0006268 GO:0006304 GO:0006265 GO:0005694 GO:0003917 -

String Network

Link to STRINGS	STRINGS Network
MMP0956

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