Desulfovibrio vulgaris Hildenborough Module 4 Residual: 0.45 | Syntrophy Portal

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Summary

Residual: 0.45 Score: -42.339 version: dvh_cmonkey_11_Mar_02

Members

DVU0483 DNA mismatch repair protein MutL Details for DVU0483 - DNA mismatch repair protein MutL GO Terms: GO:0005524, GO:0006298, GO:0032300, GO:0030983 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0483 Tuberculist Genomic Region	DVU1839 Thioredoxin Details for DVU1839 - Thioredoxin GO Terms: GO:0045454, GO:0006662, GO:0015035 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU1839 Tuberculist Genomic Region
DVU0595 Uncharacterized protein Details for DVU0595 - Uncharacterized protein GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0595 Tuberculist Genomic Region	DVU1874 Chaperone protein ClpB Details for DVU1874 - Chaperone protein ClpB GO Terms: GO:0005524, GO:0005737, GO:0016485, GO:0009408 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU1874 Tuberculist Genomic Region
DVU0662 Serine O-acetyltransferase Details for DVU0662 - Serine O-acetyltransferase GO Terms: GO:0009001 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0662 Tuberculist Genomic Region	DVU2324 Copper-translocating P-type ATPase Details for DVU2324 - Copper-translocating P-type ATPase GO Terms: GO:0005524, GO:0005507, GO:0004008, GO:0016021 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU2324 Tuberculist Genomic Region
DVU0663 Cysteine synthase Details for DVU0663 - Cysteine synthase GO Terms: GO:0006535, GO:0004124, GO:0016740 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0663 Tuberculist Genomic Region	DVU2439 Efflux transporter, RND family, MFP subunit Details for DVU2439 - Efflux transporter, RND family, MFP subunit GO Terms: GO:0016020, GO:0055085 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU2439 Tuberculist Genomic Region
DVU0664 Cysteine desulfurase Details for DVU0664 - Cysteine desulfurase GO Terms: GO:0006520, GO:0031071, GO:0016829, GO:0030170 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0664 Tuberculist Genomic Region	DVU2467 Ribonuclease R Details for DVU2467 - Ribonuclease R GO Terms: GO:0003723, GO:0005737, GO:0008859 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU2467 Tuberculist Genomic Region
DVU0725 Uncharacterized protein Details for DVU0725 - Uncharacterized protein GO Terms: GO:0003824 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0725 Tuberculist Genomic Region	DVU2468 Tetraacyldisaccharide 4'-kinase Details for DVU2468 - Tetraacyldisaccharide 4'-kinase GO Terms: GO:0005524, GO:0009245, GO:0009029 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU2468 Tuberculist Genomic Region
DVU0812 Protein GrpE Details for DVU0812 - Protein GrpE GO Terms: GO:0000774, GO:0005737, GO:0006457 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU0812 Tuberculist Genomic Region	DVU2469 Uncharacterized protein Details for DVU2469 - Uncharacterized protein GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU2469 Tuberculist Genomic Region
DVU1013 Type I secretion outer membrane protein, TolC family Details for DVU1013 - Type I secretion outer membrane protein, TolC family GO Terms: GO:0019867, GO:0005215 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU1013 Tuberculist Genomic Region	DVU2974 Uncharacterized protein Details for DVU2974 - Uncharacterized protein GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU2974 Tuberculist Genomic Region
DVU1212 FxsA protein Details for DVU1212 - FxsA protein GO Terms: GO:0016020 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU1212 Tuberculist Genomic Region	DVU3283 Uncharacterized protein Details for DVU3283 - Uncharacterized protein GO Terms: NA PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU3283 Tuberculist Genomic Region
DVU1629 Ribosomal subunit interface protein Details for DVU1629 - Ribosomal subunit interface protein GO Terms: GO:0044238 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU1629 Tuberculist Genomic Region	DVU3316 Dihydroorotate dehydrogenase Details for DVU3316 - Dihydroorotate dehydrogenase GO Terms: GO:0006207, GO:0006222, GO:0005737, GO:0004152 PATRIC Pathways: NA Essentiality: Griffin Essential: NA \| In vitro Essential: NA \| In vivo Essential: NA Go to Gene Page: DVU3316 Tuberculist Genomic Region

Motifs

Motif 1:

e-value: 3.1 Motif 2:

e-value: 2600

Module Median Expression Profiles

Module Plots

Regulation

Regulator	Interaction	Influence Weight	Other Influences
DVU0596 DNA-binding response regulator LytR	up-regulates	0.14	DVU0596
DVU0744 Sigma-54 dependent transcriptional regulator/response regulator	up-regulates	0.19	DVU0744
DVU0813 Heat-inducible transcription repressor HrcA	up-regulates	0.31	DVU0813
DVU1730 DNA-binding protein	up-regulates	0.13	DVU1730
DVU2547 Transcriptional regulator, putative	up-regulates	0.18	DVU2547
DVU3111 Transcriptional regulator, Crp/Fnr family	up-regulates	0.10	DVU3111

GO Enrichment

Category: BP
Category	GO ID	GO Term	Annotated	Expected	Significant	p-value
BP	GO:0000096	sulfur amino acid metabolic process	3	0.04	1	0.0400
BP	GO:0000097	sulfur amino acid biosynthetic process	3	0.04	1	0.0400
BP	GO:0009069	serine family amino acid metabolic proce...	3	0.04	1	0.0400
BP	GO:0006520	cellular amino acid metabolic process	27	0.37	2	0.0450

Category: MF
Category	GO ID	GO Term	Annotated	Expected	Significant	p-value
MF	GO:0008374	O-acyltransferase activity	3	0.02	1	0.0186
MF	GO:0030554	adenyl nucleotide binding	304	1.90	5	0.0215
MF	GO:0017076	purine nucleotide binding	333	2.08	5	0.0317
MF	GO:0030234	enzyme regulator activity	6	0.04	1	0.0370
MF	GO:0016407	acetyltransferase activity	7	0.04	1	0.0430

Essentiality

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