Methanococcus maripaludis S2 Module 20 Residual: 0.26

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Summary

Residual: 0.26 Score: -16.5334 version: mmp_cmonkey_11_Oct_11

Members

MMP0045 bifunctional short chain isoprenyl diphosphate synthase (NCBI)

Details for MMP0045 - bifunctional short chain isoprenyl diphosphate synthase (NCBI)

GO Terms: GO:0008299

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0045

Tuberculist Genomic Region

MMP1707 translation initiation factor aIF-2, subunit alpha (NCBI)

Details for MMP1707 - translation initiation factor aIF-2, subunit alpha (NCBI)

GO Terms: GO:0006412, GO:0005850, GO:0003723, GO:0003743

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1707

Tuberculist Genomic Region

MMP0046 conserved hypothetical protein (NCBI)

Details for MMP0046 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0046

Tuberculist Genomic Region

MMP1710 conserved hypothetical archeal protein (NCBI)

Details for MMP1710 - conserved hypothetical archeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1710

Tuberculist Genomic Region

MMP0596 RNA 2'-O-methyl modification protein (NOP5/NOP56) (NCBI)

Details for MMP0596 - RNA 2'-O-methyl modification protein (NOP5/NOP56) (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0596

Tuberculist Genomic Region

MMP0044 conserved hypothetical protein (NCBI)

Details for MMP0044 - conserved hypothetical protein (NCBI)

GO Terms: GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0044

Tuberculist Genomic Region

MMP0901 ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

Details for MMP0901 - ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

GO Terms: GO:0015684, GO:0016021, GO:0005622, GO:0009276, GO:0015093, GO:0005525

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0901

Tuberculist Genomic Region

MMP0093 Ribosomal protein L21e (NCBI)

Details for MMP0093 - Ribosomal protein L21e (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0093

Tuberculist Genomic Region

MMP1131 peptide chain release factor aRF, subunit 1 (NCBI)

Details for MMP1131 - peptide chain release factor aRF, subunit 1 (NCBI)

GO Terms: GO:0006415, GO:0005737, GO:0008547, GO:0016149, GO:0003924

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1131

Tuberculist Genomic Region

MMP1473 conserved hypothetical protein (NCBI)

Details for MMP1473 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1473

Tuberculist Genomic Region

MMP1208 translation initiation factor aIF-2, subunit gamma (NCBI)

Details for MMP1208 - translation initiation factor aIF-2, subunit gamma (NCBI)

GO Terms: GO:0005525, GO:0003924

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1208

Tuberculist Genomic Region

MMP1474 Isoleucyl-tRNA synthetase (NCBI)

Details for MMP1474 - Isoleucyl-tRNA synthetase (NCBI)

GO Terms: GO:0006428, GO:0005737, GO:0005524, GO:0004822

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1474

Tuberculist Genomic Region

MMP1318 Lysyl-tRNA synthetase (NCBI)

Details for MMP1318 - Lysyl-tRNA synthetase (NCBI)

GO Terms: GO:0006430, GO:0017101, GO:0005737, GO:0004824, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1318

Tuberculist Genomic Region

MMP1509 conserved hypothetical protein (NCBI)

Details for MMP1509 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1509

Tuberculist Genomic Region

MMP1443 GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain:Small GTP-binding protein domain (NCBI)

Details for MMP1443 - GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain:Small GTP-binding protein domain (NCBI)

GO Terms: GO:0015684, GO:0005622, GO:0016021, GO:0009276, GO:0005525, GO:0015093

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1443

Tuberculist Genomic Region

MMP1705 conserved hypothetical archeal protein (NCBI)

Details for MMP1705 - conserved hypothetical archeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1705

Tuberculist Genomic Region

MMP1444 Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2 (NCBI)

Details for MMP1444 - Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2 (NCBI)

GO Terms: GO:0006508, GO:0004239

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1444

Tuberculist Genomic Region

MMP1708 SSU ribosomal protein S27E (NCBI)

Details for MMP1708 - SSU ribosomal protein S27E (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1708

Tuberculist Genomic Region

MMP1445 GMP synthase (glutamine-hydrolyzing) (NCBI)

Details for MMP1445 - GMP synthase (glutamine-hydrolyzing) (NCBI)

GO Terms: GO:0006177, GO:0006541, GO:0005524, GO:0003922

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1445

Tuberculist Genomic Region

MMP1709 LSU ribosomal protein L44E (NCBI)

Details for MMP1709 - LSU ribosomal protein L44E (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1709

Tuberculist Genomic Region

MMP1706 conserved hypothetical protein (NCBI)

Details for MMP1706 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1706

Tuberculist Genomic Region

Displaying 1 - 21 of 21

Motifs

Motif 1: e-value: 17 e-value: 10000

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)

MMP0631

putatuve iron dependent repressor (NCBI)
 down-regulates -0.49

MMP0097

MMP0631

MMP1137

Lrp-Like Transcriptional regulatory proteins, AsnC family (NCBI)

MMP1646

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.47

MMP1137

MMP1646

MMP0041

transcription initiation factor B (NCBI)
 down-regulates -0.29

MMP0041

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP0480

conserved hypothetical protein (NCBI)
 down-regulates -0.28

MMP0052

MMP0480

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)

MMP1052

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.17

MMP0097

MMP1052

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)
 up-regulates 0.17

MMP0052

MMP0097

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0044723 single-organism carbohydrate metabolic p... 7 0.04 1 0.0360
BP GO:0032787 monocarboxylic acid metabolic process 9 0.05 1 0.0470
Category: CC
Category GO ID GO Term Annotated Expected Significant p-value
CC GO:0044424 intracellular part 71 1.96 5 0.0085
CC GO:0032991 macromolecular complex 41 1.13 4 0.0097
CC GO:0005622 intracellular 76 2.10 5 0.0121
CC GO:0005623 cell 85 2.35 5 0.0214
CC GO:0044464 cell part 85 2.35 5 0.0214
CC GO:0044444 cytoplasmic part 34 0.94 3 0.0466
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0005525 GTP binding 22 0.28 3 0.0021
MF GO:0019001 guanyl nucleotide binding 22 0.28 3 0.0021
MF GO:0032561 guanyl ribonucleotide binding 22 0.28 3 0.0021
MF GO:0043167 ion binding 220 2.85 7 0.0074
MF GO:0035639 purine ribonucleoside triphosphate bindi... 169 2.19 6 0.0096
MF GO:0001883 purine nucleoside binding 171 2.21 6 0.0102
MF GO:0017076 purine nucleotide binding 171 2.21 6 0.0102
MF GO:0032549 ribonucleoside binding 171 2.21 6 0.0102
MF GO:0032550 purine ribonucleoside binding 171 2.21 6 0.0102
MF GO:0032555 purine ribonucleotide binding 171 2.21 6 0.0102
MF GO:0001882 nucleoside binding 172 2.23 6 0.0105
MF GO:0032553 ribonucleotide binding 181 2.34 6 0.0137
MF GO:0097367 carbohydrate derivative binding 182 2.35 6 0.0141
MF GO:0097159 organic cyclic compound binding 329 4.26 8 0.0182
MF GO:1901363 heterocyclic compound binding 329 4.26 8 0.0182
MF GO:0043168 anion binding 196 2.54 6 0.0204
MF GO:0000166 nucleotide binding 200 2.59 6 0.0226
MF GO:1901265 nucleoside phosphate binding 200 2.59 6 0.0226
MF GO:0005488 binding 431 5.58 9 0.0252
MF GO:0036094 small molecule binding 210 2.72 6 0.0287

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