Methanococcus maripaludis S2 Module 51 Residual: 0.46

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Summary

Residual: 0.46 Score: -10.1082 version: mmp_cmonkey_11_Oct_11

Members

MMP0074 Conserved hypothetical Archael protein (NCBI)

Details for MMP0074 - Conserved hypothetical Archael protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0074

Tuberculist Genomic Region

MMP0670 conserved hypothetical protein (NCBI)

Details for MMP0670 - conserved hypothetical protein (NCBI)

GO Terms: GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0670

Tuberculist Genomic Region

MMP0091 conserved hypothetical archaeal protein (NCBI)

Details for MMP0091 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0091

Tuberculist Genomic Region

MMP0884 hypothetical protein (NCBI)

Details for MMP0884 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0884

Tuberculist Genomic Region

MMP0440 DNA-directed RNA polymerase subunit E' (NCBI)

Details for MMP0440 - DNA-directed RNA polymerase subunit E' (NCBI)

GO Terms: GO:0006350, GO:0005634, GO:0003677, GO:0003901, GO:0003723, GO:0003902, GO:0003899, GO:0003900

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0440

Tuberculist Genomic Region

MMP0901 ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

Details for MMP0901 - ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

GO Terms: GO:0015684, GO:0016021, GO:0005622, GO:0009276, GO:0015093, GO:0005525

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0901

Tuberculist Genomic Region

MMP0441 DNA-directed RNA polymerase subunit E (NCBI)

Details for MMP0441 - DNA-directed RNA polymerase subunit E (NCBI)

GO Terms: GO:0045941, GO:0005634, GO:0003899, GO:0003900, GO:0008159, GO:0003901, GO:0008270, GO:0003902

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0441

Tuberculist Genomic Region

MMP1064 RNA-binding region RNP-1 (RNA recognition motif):Adenylate cyclase (NCBI)

Details for MMP1064 - RNA-binding region RNP-1 (RNA recognition motif):Adenylate cyclase (NCBI)

GO Terms: GO:0006171, GO:0008294

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1064

Tuberculist Genomic Region

MMP0671 conserved hypothetical protein (NCBI)

Details for MMP0671 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0671

Tuberculist Genomic Region

MMP1431 2-phosphoglycerate kinase (NCBI)

Details for MMP1431 - 2-phosphoglycerate kinase (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1431

Tuberculist Genomic Region

MMP0695 proteasome, subunit beta (NCBI)

Details for MMP0695 - proteasome, subunit beta (NCBI)

GO Terms: GO:0006511, GO:0005839, GO:0004175, GO:0004298, GO:0004299

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0695

Tuberculist Genomic Region

MMP1590 conserved hypothetical protein (NCBI)

Details for MMP1590 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1590

Tuberculist Genomic Region

MMP1380 Chlorohydrolase (NCBI)

Details for MMP1380 - Chlorohydrolase (NCBI)

GO Terms: GO:0016787, GO:0016810

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1380

Tuberculist Genomic Region

MMP0046 conserved hypothetical protein (NCBI)

Details for MMP0046 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0046

Tuberculist Genomic Region

MMP1381 Beta-lactamase-like:ATP/GTP-binding site motif A (P-loop) (NCBI)

Details for MMP1381 - Beta-lactamase-like:ATP/GTP-binding site motif A (P-loop) (NCBI)

GO Terms: GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1381

Tuberculist Genomic Region

MMP0142 Thiamine pyrophosphate dependent enzyme related to acetolactate synthase (NCBI)

Details for MMP0142 - Thiamine pyrophosphate dependent enzyme related to acetolactate synthase (NCBI)

GO Terms: GO:0000287, GO:0003984, GO:0030976

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0142

Tuberculist Genomic Region

MMP1399 Aspartate/glutamate/uridylate kinase (NCBI)

Details for MMP1399 - Aspartate/glutamate/uridylate kinase (NCBI)

GO Terms: GO:0008652

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1399

Tuberculist Genomic Region

MMP0442 conserved hypothetical protein (NCBI)

Details for MMP0442 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0442

Tuberculist Genomic Region

MMP1594 conserved hypothetical protein (NCBI)

Details for MMP1594 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1594

Tuberculist Genomic Region

MMP0443 SSU ribosomal protein S24E (NCBI)

Details for MMP0443 - SSU ribosomal protein S24E (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0000166, GO:0003735

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0443

Tuberculist Genomic Region

MMP0116 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI)

Details for MMP0116 - N-acetyl-gamma-glutamyl-phosphate reductase (NCBI)

GO Terms: GO:0006526, GO:0005737, GO:0003942, GO:0051287, GO:0046983

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0116

Tuberculist Genomic Region

MMP0444 SSU ribosomal protein S27AE (NCBI)

Details for MMP0444 - SSU ribosomal protein S27AE (NCBI)

GO Terms: GO:0006412, GO:0005840, GO:0003735, GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0444

Tuberculist Genomic Region

MMP0141 conserved archaeal protein (NCBI)

Details for MMP0141 - conserved archaeal protein (NCBI)

GO Terms: GO:0006265, GO:0006268, GO:0005694, GO:0003916

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0141

Tuberculist Genomic Region

MMP0694 Beta-lactamase-like:KH domain (NCBI)

Details for MMP0694 - Beta-lactamase-like:KH domain (NCBI)

GO Terms: GO:0003723, GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0694

Tuberculist Genomic Region

MMP0268 tRNA pseudouridine synthase Related (NCBI)

Details for MMP0268 - tRNA pseudouridine synthase Related (NCBI)

GO Terms: GO:0001522, GO:0003723, GO:0004730, GO:0016439

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0268

Tuberculist Genomic Region

MMP1432 Adenylosuccinate synthase (NCBI)

Details for MMP1432 - Adenylosuccinate synthase (NCBI)

GO Terms: GO:0006164, GO:0004019, GO:0005525

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1432

Tuberculist Genomic Region

MMP0286 conserved hypothetical protein (NCBI)

Details for MMP0286 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0286

Tuberculist Genomic Region

MMP1444 Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2 (NCBI)

Details for MMP1444 - Metallopeptidase family M24:Methionine aminopeptidase:Methionine aminopeptidase, subfamily 2 (NCBI)

GO Terms: GO:0006508, GO:0004239

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1444

Tuberculist Genomic Region

Displaying 1 - 28 of 28

Motifs

Motif 1: e-value: 7300 e-value: 28000

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)
 down-regulates -0.38

MMP0097

MMP0036

Transcription factor E (NCBI)

MMP0840

Transcriptional regulator, TetR Family Member (NCBI)
 up-regulates 0.33

MMP0036

MMP0840

MMP1015

Transcription factor CBF/NF-Y/archaeal histone:Histone-fold/TFIID-TAF/NF-Y domain (NCBI)
 down-regulates -0.21

MMP1015

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006167 AMP biosynthetic process 3 0.02 1 0.0160
BP GO:0046033 AMP metabolic process 3 0.02 1 0.0160
BP GO:0042451 purine nucleoside biosynthetic process 5 0.03 1 0.0260
BP GO:0046129 purine ribonucleoside biosynthetic proce... 5 0.03 1 0.0260
BP GO:0042278 purine nucleoside metabolic process 7 0.04 1 0.0360
BP GO:0046128 purine ribonucleoside metabolic process 7 0.04 1 0.0360
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016772 transferase activity, transferring phosp... 12 0.20 2 0.0160

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